Results 41 to 50 of about 24,054 (230)
Advanced Science, EarlyView.The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang +14 more
wiley +1 more source
Gastroenterology Research and Practice, 2013 Gastric intestinal metaplasia is an important stage in the development of gastric cancer. Limited data is available regarding the prevalence of gastric intestinal metaplasia in the United States.
Tarek Almouradi +2 more
doaj +1 more source
Research advancements and evaluation of multifactor‐induced murine models for gastric cancer
Animal Models and Experimental Medicine, EarlyView.Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang +5 more
wiley +1 more source
CYTOKINES AS PREDICTORS OF INTESTINAL METAPLASIA OF STOMACH
Медицинская иммунология, 2019 An inflammatory process accompanied by the changes in mucosal microbiota is underlying the gastroduodenal diseases. Chronic inflammation of gastric mucosa is developed and supported by secretion of pro-inflammatory and anti-inflammatory cytokines by ...
L. V. Matveeva
doaj +1 more source
Is intestinal metaplasia of the stomach reversible? [PDF]
Gut, 2003 Intestinal metaplasia (IM) of the stomach is a risk factor in developing intestinal-type gastric cancer and hence the question of reversibility is vital. There is emerging epidemiological evidence that with long term follow up, IM may be reversible although a combination of antioxidant agents and eradication of H pylori may be necessary to achieve this.
openaire +3 more sources
Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells
BioEssays, EarlyView.Primary cilia are developmentally essential subcellular signaling compartments. However, many differentiated cells lack primary cilia, and cilia disassembly in these tissue contexts has been largely overlooked. We highlight several pathways for primary cilia loss and examine how changes in ciliation states could contribute to diverse pathologies ...
Carolyn M. Ott, Saikat Mukhopadhyay
wiley +1 more source
Anatomical predilection of intestinal metaplasia based on 78,335 endoscopic cases
The Saudi Journal of Gastroenterology, 2016 Background/Aims: Gastric intestinal metaplasia (IM) is an important risk factor for intestinal-type gastric carcinoma, and successful treatment critically depends on its timely detection.
Xin-Yi Mao +6 more
doaj +1 more source
Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development
Developmental Dynamics, EarlyView.Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin +8 more
wiley +1 more source
Emerging Frontiers in Food Allergy Treatment: Progress, Challenges, and Prospects
Food Frontiers, EarlyView.Food allergy is a rising global health concern with limited treatment options beyond allergen avoidance and emergency care. This review explores the evolving therapeutic landscape, highlighting advances in allergen immunotherapy, biologics such as monoclonal antibodies, and emerging vaccine‐based approaches.
Ayesha Zahid +3 more
wiley +1 more source
Prevalence of High-Risk Groups for Gastric Carcinoma – A Biopsy Finding
Nepalese Medical Journal, 2018 Introduction: Gastric carcinoma is leading cause of death world wide including Nepal. The 5 years survival rate of gastric carcinoma (25%) has drastically decreased compared to early gastric cancers (90-90%) hence implying the need for early detection ...
Geetika KC +2 more
doaj +1 more source