Results 51 to 60 of about 401,397 (233)

A pSMAD/CDX2 Complex Is Essential for the Intestinalization of Epithelial Metaplasia

Cell Reports, 2014
The molecular mechanisms leading to epithelial metaplasias are poorly understood. Barrett's esophagus is a premalignant metaplastic change of the esophageal epithelium into columnar epithelium, occurring in patients suffering from gastroesophageal reflux
Luigi Mari, Francesca Milano, Kaushal Parikh, Danielle Straub, Vincent Everts, Kees K. Hoeben, Paul Fockens, Navtej S. Buttar, Kausilia K. Krishnadath   +8 more
doaj   +1 more source

Müllerianosis with intestinal metaplasia: a case report [PDF]

Turkish Journal of Pathology, 2015
Müllerianosis or Müllerian choristomas are developmental alterations that consist of an organoid structure with normal Müllerian tissue. We present a 62-year-old patient diagnosed on ultrasound scanning and on CT scan of bilateral ovarian cysts. During surgery, a left ovarian cyst and retroperitoneal tumor (adhered to sigmoid serous surface) were found.
Sofía, Del Carmen, Marta, Rodríguez, M Asunción, Gómez, Miguel Ángel, Cruz, M Antonia, Núñez, Magdalena, Sancho   +5 more
openaire   +2 more sources

Advanced Imaging for Characterization of Intestinal Metaplasia [PDF]

, 2013
Gastric intestinal metaplasia is clinically relevant because of its role in the process of gastric carcinogenesis. The current gold standard for the diagnosis of intestinal metaplasia is histology.
Kwek, A Boon Eu, Ang, T Leong
core   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

Blood Biomarkers of Helicobacter pylori‐Infected Chronic Gastritis in Active Versus Stable Phases: A Clinical Indicator Analysis Combined With Proteomic and Metabolomic Investigations

iMetaMed, EarlyView.
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang, Zhen Ma, Yang Li, Shaoli Wang, Yanjiao Zhang, Lei Song, Xianyu Li, Zhen Liu   +7 more
wiley   +1 more source

Intestinal metaplasia and glandular atrophy in patients with chronic gastritis in Ilorin

Sahel Medical Journal, 2018
Background: Intestinal metaplasia and glandular atrophy are pre malignant conditions occurring as a complication of prolonged, untreated or poorly treated chronic gastritis.
David Eyitayo Ibikunle, Olatunde O Kazeem Ibrahim, Enoch O Abiodun Afolayan   +2 more
doaj   +1 more source

Precancerous Significance of Colonic Type Intestinal Metaplasia

, 1981
Numerous epidemiologic, morphologic and experimental studies have demonstrated the precancerous significance of intestinal metaplasia. We report here the results of a histochemical study of intestinal metaplasia in which 2 types were observed: one with ...
Loredana Bozzola, Carla Arslan Pagnini
core   +1 more source

Inverse Association Between Gluteofemoral Obesity and Risk of Non-Cardia Gastric Intestinal Metaplasia [PDF]

, 2023
BACKGROUND & AIMS: It is unclear whether obesity confers increased risk of non-cardia gastric adenocarcinoma and its precursor, gastric intestinal metaplasia.
Tan, Mimi C, Thrift, Aaron P, El-Serag, Hashem B, Jove, Andre G, Holmes, Hudson M   +4 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Gastric Intestinal Metaplasia in an Underserved Population in the USA: Prevalence, Epidemiologic and Clinical Features

Gastroenterology Research and Practice, 2013
Gastric intestinal metaplasia is an important stage in the development of gastric cancer. Limited data is available regarding the prevalence of gastric intestinal metaplasia in the United States.
Tarek Almouradi, Tadd Hiatt, Bashar Attar   +2 more
doaj   +1 more source