Results 51 to 60 of about 741,485 (265)

High expression of Cathepsin E in tissues but not blood of patients with Barrett’s esophagus and adenocarcinoma [PDF]

, 2014
Background Cathepsin E (CTSE), an aspartic proteinase, is differentially expressed in the metaplasia–dysplasia–neoplasia sequence of gastric and colon cancer.
Bobryshev, Yuri V., Botelho, Natalia K., Falkenback, Dan,, Fisher, Oliver M., Freeman, Araluen K., Levert-Mignon, Angelique J., Lord, Reginald V., Lord, Sarah J., Lund University., Thomas, Melissa L., Wettstein, Antony, Whiteman, David C.   +11 more
core   +2 more sources

CORRELACION DE LOS HALLAZGOS ENDOSCOPICOS E HISTOLOGICOS EN EL DIAGNOSTICO DE METAPLASIAINTESTINAL GASTRICA EN PACIENTES EN EL HOSPITAL NACIONAL HIPOLITO UNANUE EN EL AÑO 2015

Revista de la Facultad de Medicina Humana, 2017
Objetivos: Determinar la correlación entre los hallazgos endoscópicos sugestivos de metaplasia y su contraparte histológica en nuestro medio, dentro de ellos también determinar algunos factores asociados.
José M. Vela- Ruiz, María Esther Alba Rodríguez   +1 more
doaj   +1 more source

The staging of gastritis with the olga system in the italian setting. histological features and gastric cancer risk [PDF]

, 2017
BACKGROUND: Recently OLGA (Operative Link on Gastritis Assessment) classification has been proposed to identify high-risk forms of gastritis that can evolve in gastric cancer (stages III and IV).
Alvaro, Domenico, Cannaviello, Claudio, Efrati, Cesare, Finizio, Roberto, Giulitti, Diego, Mangogna, LIVIA MARIA, o Sed, Nicole Piazza, Ridola, Lorenzo, Taccogna, Silvia, Valabrega, Stefano   +9 more
core   +1 more source

Diagnosis and Management of Gastric Intestinal Metaplasia: Current Status and Future Directions

Gut and Liver, 2019
Gastric intestinal metaplasia (GIM) is a known premalignant condition of the human stomach along the pathway to gastric cancer (GC). Histologically, GIM represents the replacement of normal gastric mucosa by mucin-secreting intestinal mucosa ...
Robert J. Huang, A. Choi, C. Truong, M. Yeh, J. Hwang   +4 more
semanticscholar   +1 more source

AGA Institute Technical Review on Gastric Intestinal Metaplasia – Part 1

Gastroenterology, 2019
Gastric cancer is the third leading cause of cancer-related mortality and the fifth most common cancer globally.1 There is clear racial and ethnic and geographic variation in disease burden worldwide with populations and regions of high and low incidence.
A. Gawron, Shailja C. Shah, Osama Altayar, Perica Davitkov, M. Douglas, T. Kevin, R. Mustafa   +6 more
semanticscholar   +1 more source

Prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease : systematic review. [PDF]

, 2003
Objectives: To ascertain the prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease and its association with the disease.
Childs, S., Hungin, A. P. S., Raghunath, A., Wooff, D.   +3 more
core   +2 more sources

A pSMAD/CDX2 Complex Is Essential for the Intestinalization of Epithelial Metaplasia

Cell Reports, 2014
The molecular mechanisms leading to epithelial metaplasias are poorly understood. Barrett's esophagus is a premalignant metaplastic change of the esophageal epithelium into columnar epithelium, occurring in patients suffering from gastroesophageal reflux
Luigi Mari, Francesca Milano, Kaushal Parikh, Danielle Straub, Vincent Everts, Kees K. Hoeben, Paul Fockens, Navtej S. Buttar, Kausilia K. Krishnadath   +8 more
doaj   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

A case of Helicobacter pylori-negative early gastric adenocarcinoma with gastrointestinal phenotype

Endoscopy International Open, 2021
A 40-year-old man with slightly depressed (0-IIc) type gastric cancer of the pyloric anterior gastric area underwent pre-operative screening for tetralogy of Fallot and endoscopic submucosal dissection (ESD) and was tested for Helicobacter pylori ...
Masafumi Takatsuna, Rie Azumi, Takeshi Mizusawa, Hiroki Sato, Ken-Ichi Mizuno, Takashi Kato, Junji Yokoyama, Yoichi Ajioka, Shuji Terai   +8 more
doaj   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source