Results 61 to 70 of about 672,198 (306)

Diagnosis and Management of Gastric Intestinal Metaplasia: Current Status and Future Directions

Gut and Liver, 2019
Gastric intestinal metaplasia (GIM) is a known premalignant condition of the human stomach along the pathway to gastric cancer (GC). Histologically, GIM represents the replacement of normal gastric mucosa by mucin-secreting intestinal mucosa ...
Robert J. Huang, A. Choi, C. Truong, M. Yeh, J. Hwang   +4 more
semanticscholar   +1 more source

Two distinct aetiologies of cardia cancer, evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status [PDF]

, 2007
Background: Non-cardia gastric adenocarcinoma is positively associated with Helicobacter pylori infection and atrophic gastritis. The role of H pylori infection and atrophic gastritis in cardia cancer is unclear.
Aase, S., Derakhshan, M.H., Fyfe, V., Hansen, S., Jellum, E., McColl, K.E.L., Melby, K.K., Vollset, S.E.   +7 more
core   +2 more sources

A pSMAD/CDX2 Complex Is Essential for the Intestinalization of Epithelial Metaplasia

Cell Reports, 2014
The molecular mechanisms leading to epithelial metaplasias are poorly understood. Barrett's esophagus is a premalignant metaplastic change of the esophageal epithelium into columnar epithelium, occurring in patients suffering from gastroesophageal reflux
Luigi Mari, Francesca Milano, Kaushal Parikh, Danielle Straub, Vincent Everts, Kees K. Hoeben, Paul Fockens, Navtej S. Buttar, Kausilia K. Krishnadath   +8 more
doaj   +1 more source

A case of Helicobacter pylori-negative early gastric adenocarcinoma with gastrointestinal phenotype

Endoscopy International Open, 2021
A 40-year-old man with slightly depressed (0-IIc) type gastric cancer of the pyloric anterior gastric area underwent pre-operative screening for tetralogy of Fallot and endoscopic submucosal dissection (ESD) and was tested for Helicobacter pylori ...
Masafumi Takatsuna, Rie Azumi, Takeshi Mizusawa, Hiroki Sato, Ken-Ichi Mizuno, Takashi Kato, Junji Yokoyama, Yoichi Ajioka, Shuji Terai   +8 more
doaj   +1 more source

AGA Institute Technical Review on Gastric Intestinal Metaplasia – Part 1

Gastroenterology, 2019
Gastric cancer is the third leading cause of cancer-related mortality and the fifth most common cancer globally.1 There is clear racial and ethnic and geographic variation in disease burden worldwide with populations and regions of high and low incidence.
A. Gawron, Shailja C. Shah, Osama Altayar, Perica Davitkov, Morgan Douglas, Turner Kevin, R. Mustafa   +6 more
semanticscholar   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F.E. Barth, Julia P. Mosler, Anna Härle, Stephanie E. Weissinger, Nadine T. Gaisa, Peter Möller, Nico Fischer, Chantal Allgöwer, J.‐Matthias Löhr, Dirk Grimm, Thomas Seufferlein, Stefan Liebau, Ninel Azoitei, Michael K. Melzer, Frank Arnold, Johann Gout, Alexander Kleger   +20 more
wiley   +1 more source

Müllerianosis with intestinal metaplasia: a case report [PDF]

Turkish Journal of Pathology, 2015
Müllerianosis or Müllerian choristomas are developmental alterations that consist of an organoid structure with normal Müllerian tissue. We present a 62-year-old patient diagnosed on ultrasound scanning and on CT scan of bilateral ovarian cysts. During surgery, a left ovarian cyst and retroperitoneal tumor (adhered to sigmoid serous surface) were found.
Sofía, Del Carmen, Marta, Rodríguez, M Asunción, Gómez, Miguel Ángel, Cruz, M Antonia, Núñez, Magdalena, Sancho   +5 more
openaire   +2 more sources

The pathologists’ eyes on foregut: histopathological relations in the experimental and routine diagnostics [PDF]

, 2011
SUMMARY I. The study aimed to investigate the incidence of duodeno-gastroesophageal reflux-induced malignoma formation in a series of duodeno-esophageal anastomosis operations in rats.
Németh István Balázs
core  

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

Advanced Science, EarlyView.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu, Fa‐Peng Zhang, Chao Qin, Zhi‐Xiao Song, Cai‐Ni Yang, Shu‐Sheng Lin, Xian‐Huan Yu, Wen‐Rui Wu, Chao‐Qun Liu, Chao Liu, Lei‐Bo Xu   +10 more
wiley   +1 more source

Intestinal metaplasia and glandular atrophy in patients with chronic gastritis in Ilorin

Sahel Medical Journal, 2018
Background: Intestinal metaplasia and glandular atrophy are pre malignant conditions occurring as a complication of prolonged, untreated or poorly treated chronic gastritis.
David Eyitayo Ibikunle, Olatunde O Kazeem Ibrahim, Enoch O Abiodun Afolayan   +2 more
doaj   +1 more source