Results 81 to 90 of about 24,054 (230)

A Cell Marker Atlas to Distinguish Metaplastic Transitions in Human Esophagus and Stomach

Cellular and Molecular Gastroenterology and Hepatology
Metaplasia is an adaptative response to injury and inflammation and can be a precursor to dysplasia and cancer. Metaplasia in the esophagus, termed Barrett’s esophagus, is the replacement of the stratified squamous epithelium by glandular tissue ...
Karen J. Dunbar, Su-Hyung Lee, Yoonkyung Won, Emily M. Esquea, Jeong Yun Yang, Daniel O. Kechele, Sandra Ryeom, Julian A. Abrams, Frank D. McKeon, James M. Wells, Micheal Quante, Eunyoung Choi, Jianwen Que, Timothy C. Wang, Anil K. Rustgi, James R. Goldenring   +15 more
doaj   +1 more source

Assessing the effectiveness of texture and color enhancement imaging versus white‐light endoscopy in detecting gastrointestinal lesions: A systematic review and meta‐analysis

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Introduction Gastrointestinal cancers account for 26% of cancer incidence and 35% of cancer‐related deaths globally. Early detection is crucial but often limited by white light endoscopy (WLE), which misses subtle lesions. Texture and color enhancement imaging (TXI), introduced in 2020, enhances texture, brightness, and color, addressing WLE's
Muhammad Shahzil, Talha Bin Kashif, Zainab Jamil, Muhammad Ali Khaqan, Luqman Munir, Zunaira Amjad, Muhammad Saad Faisal, Ammad Javaid Chaudhary, Hassam Ali, Shahryar Khan, Ikponmwosa Enofe   +10 more
wiley   +1 more source

A case of duodenal pyloric gland adenoma with high‐grade dysplasia arising from ectopic gastric mucosa

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Superficial non‐ampullary duodenal epithelial tumor is a rare disease, but its frequency has reportedly been increasing in recent years. We report a case of duodenal pyloric gland adenoma with high‐grade dysplasia arising from ectopic gastric mucosa.
Kenichiro Nakachi, Hironobu Nagumo, Tetsuro Okura, Wataru Ohno, Takashi Ashikawa, Tomoyuki Funato, Toshiyasu Shiratori, So Nakaji, Shion Ando   +8 more
wiley   +1 more source

Current Status of Gastric Cancer Screening and Future Perspectives

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Gastric cancer (GC) remains a major global health concern, particularly in East Asia, Central Asia, and Eastern Europe, where its incidence and mortality rates are high. Helicobacter pylori infection is the primary cause of GC and leads to carcinogenic progression from nonatrophic gastritis to cancer.
Chika Kusano, Fumiaki Ishibashi, Chikamasa Ichita, Takuji Gotoda   +3 more
wiley   +1 more source

Gastric Foveolar‐Type Hyperplastic Polyp of the Duodenum With GNAS and KRAS Mutations: A Potential Precursor to Neoplasia

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We report a gastric foveolar‐type hyperplastic polyp of the duodenum harboring mutations in the GNAS and KRAS genes. The lesion was incidentally detected during a routine upper gastrointestinal endoscopy in a man in his 50s. It appeared as a 10‐mm elevated lesion located at the superior duodenal angle.
Kenji Yamazaki, Ryoji Kushima, Noritaka Ozawa, Haruka Koizumi, Saeka Hayashi, Atsushi Soga, Koji Yamashita, Shogo Shimizu, Masahito Shimizu   +8 more
wiley   +1 more source

Helicobacter pylori with stronger intensity of CagA phosphorylation lead to an increased risk of gastric intestinal metaplasia and cancer

BMC Microbiology, 2011
Background Nearly all Taiwanese H. pylori stains are cagA-genopositive and encode CagA protein. In this study, we evaluated whether different intensity of tyrosine phosphorylated-CagA (p-CagA) had an impact on the clinical diseases and histological ...
Cheng Hsiu-Chi, Wu Jiunn-Jong, Hung Kuei-Hsiang, Sheu Shew-Meei, Yang Hsiao-Bai, Chuang Chiao-Hsiung, Chang Wei-Lun, Sheu Bor-Shyang   +7 more
doaj   +1 more source

Gastric microbiota‐specific signatures in adults with obesity and Helicobacter pylori‐negative gastritis

European Journal of Clinical Investigation, Volume 55, Issue 11, November 2025.
Abstract Background The role of the gastric microbiome in the pathophysiology of gastritis beyond Helicobacter pylori (HP) infection is poorly understood and has remained unexplored in patients with obesity. The aim of this study was to analyse gastric mucosa‐associated microbiota in patients with obesity and nonatrophic chronic gastritis in the ...
José Ignacio Martínez‐Montoro, Raquel Sancho‐Marín, Luis Ocaña‐Wilhelmi, Isabel Arranz‐Salas, Nerea Ruiz‐Campos, María José García‐López, Francisco J. Tinahones, Carolina Gutiérrez‐Repiso   +7 more
wiley   +1 more source

Modern strategy of patient management in pre-cancer stomach diseases: diagnostic approaches and therapeutic possibilities

Лечащий Врач, 2021
Stomach cancer represents a serious medical and social problem, both for most of the countries, and for Russia. Patients with chronic atrophic gastritis or intestinal metaplasia have increased risk of stomach adenocarcinoma development.
L. B. Lazebnik, E. A. Lyalyukova
doaj  

Origin of adenocarcinoma in Barrett's esophagus: P53 and Ki67 expression and histopathologic background Origem do adenocarcinoma no esôfago de Barrett: bases histopathológicas e expressão dos genes p53 e Ki67

Clinics, 2005
Barrett's esophagus is the substitution of squamous epithelium of the distal esophagus by columnar epithelium. Intestinal metaplasia in Barrett's esophagus is considered to be the main risk factor for the development of adenocarcinoma.
Sergio Szachnowicz, Ivan Cecconello, Kiyoshi Iriya, Allan Garms Marson, Flávio Roberto Takeda, Joaquim José Gama-Rodrigues   +5 more
doaj   +1 more source

Limited value of type III intestinal metaplasia in predicting risk of gastric carcinoma. [PDF]

, 1987
Keith Ramesar, D. S. A. Sanders, D. Hopwood   +2 more
openalex   +1 more source