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Diffuse-type Gastric Cancer [PDF]

open access: yesThe Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2022
Gastric cancer is the most prevalent malignant tumor in Korea. Histologically, it is often classified into intestinal-type and diffuse-type. Intestinal-type gastric cancer is known to occur mainly from chronic gastritis caused by Helicobacter pylori (H ...
Jie-Hyun Kim
doaj   +1 more source

Glutamine protects intestine against ischemia-reperfusion injury by alleviating endoplasmic reticulum stress induced apoptosis in rats [PDF]

open access: yesActa Cirúrgica Brasileira, 2020
Purpose Glutamine, as an essential part of enteral nutrition and parenteral nutrition agent, has been widely recognized to be a kind of important intestinal mucosa protectant in clinical practice and experimental research. However, the mechanisms of its
Hao Xu   +4 more
doaj   +1 more source

CDX2-induced intestinal metaplasia in human gastric organoids derived from induced pluripotent stem cells

open access: yesiScience, 2022
Summary: Intestinal metaplasia is related to gastric carcinogenesis. Previous studies have suggested the important role of CDX2 in intestinal metaplasia, and several reports have shown that the overexpression of CDX2 in mouse gastric mucosa caused ...
Takahiro Koide   +4 more
doaj   +1 more source

Regulation of psoriasis, colitis, and the intestinal microbiota by clusterin

open access: yesScientific Reports, 2023
Psoriasis, a chronic and systemic inflammatory disorder characterized by activation of the interleukin (IL)-23/IL-17 axis, may be associated with the intestinal microbiota through the so-called “gut–skin axis.” Clusterin is a glycoprotein ubiquitously ...
Yu Kyung Jun   +11 more
doaj   +1 more source

Differential response of digesta- and mucosa-associated intestinal microbiota to dietary insect meal during the seawater phase of Atlantic salmon

open access: yesAnimal Microbiome, 2021
Background Intestinal digesta is commonly used for studying responses of microbiota to dietary shifts, yet evidence is accumulating that it represents an incomplete view of the intestinal microbiota.
Yanxian Li   +5 more
doaj   +1 more source

Gut Microbiota Comparison Between Intestinal Contents and Mucosa in Mice With Repeated Stress-Related Diarrhea Provides Novel Insight

open access: yesFrontiers in Microbiology, 2021
Repeated stress-related diarrhea is a kind of functional bowel disorders (FBDs) that are mainly stemming from dysregulation of the microbiota–gut–brain axis mediated by a complex interplay of 5-hydroxytryptophan (5-HT).
Chen-Yang Zhang   +7 more
doaj   +1 more source

Reduced diversity of intestinal T-cell receptor repertoire in patients with Crohn’s disease

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
BackgroundThe intestinal microenvironment directly determines the human T-cell receptor (TCR) repertoire. Despite its extreme diversity, TCR repertoire analysis may provide a better understanding of the immune system in patients with inflammatory bowel ...
Sung Noh Hong   +7 more
doaj   +1 more source

IgG “Detoxes” the Intestinal Mucosa [PDF]

open access: yesCell Host & Microbe, 2015
Secretory IgA is important in mucosal defense, but other, incompletely understood effectors exist. In this issue of Cell Host & Microbe, Kamada et al. (2015) show that IgG antibodies are produced against surface virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epithelium, and direct their destruction by ...
Thaddeus S. Stappenbeck, Lars Eckmann
openaire   +3 more sources

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