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Diffuse-type Gastric Cancer [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2022
Gastric cancer is the most prevalent malignant tumor in Korea. Histologically, it is often classified into intestinal-type and diffuse-type. Intestinal-type gastric cancer is known to occur mainly from chronic gastritis caused by Helicobacter pylori (H ...
Jie-Hyun Kim
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Glutamine protects intestine against ischemia-reperfusion injury by alleviating endoplasmic reticulum stress induced apoptosis in rats [PDF]

Acta Cirúrgica Brasileira, 2020
Purpose Glutamine, as an essential part of enteral nutrition and parenteral nutrition agent, has been widely recognized to be a kind of important intestinal mucosa protectant in clinical practice and experimental research. However, the mechanisms of its
Hao Xu, Guangyi Liu, Haitao Gu, Jijian Wang, Yang Li   +4 more
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Regulation of psoriasis, colitis, and the intestinal microbiota by clusterin

Scientific Reports, 2023
Psoriasis, a chronic and systemic inflammatory disorder characterized by activation of the interleukin (IL)-23/IL-17 axis, may be associated with the intestinal microbiota through the so-called “gut–skin axis.” Clusterin is a glycoprotein ubiquitously ...
Yu Kyung Jun, Hee Tae Yoon, So Hyun Kwon, Ui Hyeon Jo, Ji Eun Kim, Yoo Min Han, Min-Seon Kim, Jong Pil Im, Dong Ho Lee, Joo Sung Kim, Seong-Joon Koh, Hyunsun Park   +11 more
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Gut Microbiota Comparison Between Intestinal Contents and Mucosa in Mice With Repeated Stress-Related Diarrhea Provides Novel Insight

Frontiers in Microbiology, 2021
Repeated stress-related diarrhea is a kind of functional bowel disorders (FBDs) that are mainly stemming from dysregulation of the microbiota–gut–brain axis mediated by a complex interplay of 5-hydroxytryptophan (5-HT).
Chen-Yang Zhang, Chen-Yang Zhang, Xin-Xin Peng, Hao-Qing Shao, Xiao-Ya Li, Yi Wu, Zhou-Jin Tan, Zhou-Jin Tan   +7 more
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Differential response of digesta- and mucosa-associated intestinal microbiota to dietary insect meal during the seawater phase of Atlantic salmon

Animal Microbiome, 2021
Background Intestinal digesta is commonly used for studying responses of microbiota to dietary shifts, yet evidence is accumulating that it represents an incomplete view of the intestinal microbiota.
Yanxian Li, Leonardo Bruni, Alexander Jaramillo-Torres, Karina Gajardo, Trond M. Kortner, Åshild Krogdahl   +5 more
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Reduced diversity of intestinal T-cell receptor repertoire in patients with Crohn’s disease

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundThe intestinal microenvironment directly determines the human T-cell receptor (TCR) repertoire. Despite its extreme diversity, TCR repertoire analysis may provide a better understanding of the immune system in patients with inflammatory bowel ...
Sung Noh Hong, Sung Noh Hong, Joo-Young Park, So-Yun Yang, Chansu Lee, Chansu Lee, Young-Ho Kim, Je-Gun Joung   +7 more
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The intestinal γδ T cells: functions in the gut and in the distant organs

Frontiers in Immunology, 2023
Located in the frontline against the largest population of microbiota, the intestinal mucosa of mammals has evolved to become an effective immune system.
Guo-Qing Li, Guo-Qing Li, Jiliang Xia, Weihong Zeng, Weijia Luo, Logen Liu, Xi Zeng, Deliang Cao, Deliang Cao, Deliang Cao   +9 more
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Using a ligate intestinal loop mouse model to investigate Clostridioides difficile adherence to the intestinal mucosa in aged mice.

PLoS ONE, 2021
Interaction of Clostridioides difficile spores with the intestinal mucosa contributes to the persistence and recurrence of the infection. Advanced age is one of the main risk factors for C. difficile infection and recurrence of the disease.
Pablo Castro-Córdova, María José Mendoza-León, Daniel Paredes-Sabja   +2 more
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Myosin light chain kinase mediates intestinal barrier disruption following burn injury. [PDF]

PLoS ONE, 2012
BACKGROUND: Severe burn injury results in the loss of intestinal barrier function, however, the underlying mechanism remains unclear. Myosin light chain (MLC) phosphorylation mediated by MLC kinase (MLCK) is critical to the pathophysiological regulation ...
Chuanli Chen, Pei Wang, Qin Su, Shiliang Wang, Fengjun Wang   +4 more
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Lactobacillus delbrueckii CIDCA 133 Ameliorates Chemotherapy-Induced Mucositis by Modulating Epithelial Barrier and TLR2/4/Myd88/NF-κB Signaling Pathway

Frontiers in Microbiology, 2022
Intestinal mucositis promoted by the use of anticancer drugs is characterized by ulcerative inflammation of the intestinal mucosa, a debilitating side effect in cancer patients undergoing treatment.
Fernanda Alvarenga Lima Barroso, Luís Cláudio Lima de Jesus, Tales Fernando da Silva, Viviane Lima Batista, Juliana Laguna, Nina Dias Coelho-Rocha, Kátia Duarte Vital, Simone Odília Antunes Fernandes, Valbert Nascimento Cardoso, Enio Ferreira, Flaviano Santos Martins, Mariana Martins Drumond, Mariana Martins Drumond, Pamela Mancha-Agresti, Alexander Birbrair, Debmalya Barh, Debmalya Barh, Vasco Azevedo   +17 more
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