Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection. [PDF]
, 2016 HIV targets the gut mucosa early in infection, causing immune and epithelial barrier dysfunction and disease progression. However, gut mucosal sensing and innate immune signaling through mucosal pattern recognition receptors (PRRs) during HIV infection ...
Bäumler, AJ +9 more
core +2 more sources
T‐cell activation in the intestinal mucosa [PDF]
Immunological Reviews, 2007 Summary: The vast majority of peripheral T cells exist as resting lymphocytes until a signal for activation has been received. In response to antigen, this activation involves ligation of the T‐cell receptor (TCR) and signal transmission through the CD3 complex, which then initiates a cascade of intracellular events that lead to the expression of ...
John R. Klein +2 more
openaire +3 more sources
Mediators of Inflammation, 2010 Objective. To research the protective effects and mechanisms of Radix Astragali injection on the intestinal mucosa of rats with obstructive jaundice (OJ). Methods.
Zhang Xiping +4 more
doaj +1 more source
Changes of biochemical parameters in rat intestinal mucosa induced by methotrexate and effects of enteral administration of glutamine [PDF]
Archive of Oncology, 2004 BACKGROUND: Rapidly proliferating crypt cells of the intestinal epithelium, the precursors of the mature enterocytes, are extremely sensitive to the effects of cytostatic agents. We investigated the effects of the methotrexate on rat intestinal mucosa in
Bajin-Katić Katica +2 more
doaj +1 more source
To respond or not to respond - a personal perspective of intestinal tolerance [PDF]
, 2018 For many years, the intestine was one of the poor relations of the immunology world, being a realm inhabited mostly by specialists and those interested in unusual phenomena.
A Besredka +142 more
core +1 more source
Potential role of mesenchymal stem cells in alleviating intestinal ischemia/reperfusion impairment. [PDF]
PLoS ONE, 2013 BACKGROUND: Transplantation of bone marrow mesenchymal stem cells (MSCs) provides a promising therapeutic efficiency for a variety of disorders caused by ischemia or reperfusion impairment.
Haitao Jiang +5 more
doaj +1 more source
Occurrence of gastric cancer and carcinoids in atrophic gastritis during prospective long-term follow up [PDF]
, 2015 Objective. Atrophic gastritis (AG) is a risk condition for gastric cancer and type I gastric carcinoids. Recent studies assessing the overall risk of gastric cancer and carcinoids in AG at long-term follow up are lacking.
Annibale, Bruno +6 more
core +2 more sources
International Journal of Inflammation, 2017 Crohn’s disease (CD) is a chronic inflammatory disorder, characterized by cytokine imbalance and transcription signaling pathways activation. In addition, the increase of mesenteric adipose tissue (MAT) near the affected intestinal area is a hallmark of ...
Andressa Coope +11 more
doaj +1 more source
Differences in intestinal size, structure, and function contributing to feed efficiency in broiler chickens reared at geographically distant locations [PDF]
, 2019 The contribution of the intestinal tract to differences in residual feed intake (RFI) has been inconclusively studied in chickens so far. It is also not clear if RFI-related differences in intestinal function are similar in chickens raised in different ...
Aschenbach, J. +9 more
core +1 more source
Early markers of angiogenesis and ischemia during bowel conduit neovascularization [PDF]
, 2017 Background Bowel flaps are a good and reliable method to restore the continuity of the aerodigestive tract. Radiated fields, contaminated recipient sites, or depleted recipient vessels may increase the risk for ischemic injury after transfer.
Chen, Hung-chi +7 more
core +1 more source