Results 61 to 70 of about 361,975 (346)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Regulation of apoptosis is impaired in atrophic gastritis associated with gastric cancer

BMC Gastroenterology, 2017
Background Gastric premalignant conditions, atrophic gastritis (AG) and intestinal metaplasia (IM) are characterized by an increase of proliferation and a reduction of apoptosis in epithelial cells.
R. Rosania, M. Varbanova, T. Wex, C. Langner, J. Bornschein, F. Giorgio, E. Ierardi, P. Malfertheiner   +7 more
doaj   +1 more source

Effects of microencapsulated carvacrol and cinnamaldehyde on feed digestibility, intestinal mucosa, and biochemical and antioxidant parameters in broilers [PDF]

, 2023
Caroline Schmidt Facchi, Fernanda Danieli Antoniazzi Valentini, Heloísa Pagnussatt, Felipe Leite, Alícia Dal Santo, Edemar Aniecevski, Gabriel Rossato, Gustavo Zaccaron, Davi F. Alba, Carine F. Souza, Rafaella Rossetto Petrolli, Gabriela M. Galli, Aleksandro S. Da Silva, F. de C. Tavernari, Tiago Goulart Petrolli   +14 more
openalex   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Short segment Barrett's esophagus and distal gastric intestinal metaplasia Esôfago de Barrett de segmento curto e metaplasia intestinal gástrica distal

Arquivos de Gastroenterologia, 2006
BACKGROUND: Short segment Barrett's esophagus is defined by the presence of
Judite Dietz, Sílvia Chaves-e-Silva, Luíse Meurer, Setsuo Sekine, Andréa Ribeiro de Souza, Gilmara Coelho Meine   +5 more
doaj   +1 more source

Transplantion of predominant Lactobacilli from native hens to commercial hens could indirectly regulate their ISC activity by improving intestinal microbiota

Microbial Biotechnology, 2022
Summary In poultry, HyLine (HL) Hens are known for their excellent laying performance. However, ZhenNing (ZN) Hens, a native chicken breed in China, are known for their unique flavour.
Lijuan Liu, Zhou Zhou, Yi Hong, Keyang Jiang, Lingzi Yu, Xiaochen Xie, Yuling Mi, Shu Jeffrey Zhu, Caiqiao Zhang, Jian Li   +9 more
doaj   +1 more source

Effects of glycolysis and polyamine predation on intestinal epithelial barrier in colorectal cancer

Frontiers in Oncology, 2022
Colorectal cancer (CRC) is the second most lethal cancer and the third most common cancer in the world, and its prognosis is severely affected by high intestinal mucosal permeability and increasing tumor burden.
Yu Wang, Huan He, Jingwen Chen, Zijing Song, Xuediao Pan, Tian Lan, Guixiang Wang   +6 more
doaj   +1 more source

Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis. [PDF]

, 2014
Barretts esophagus (BE) involves a metaplastic replacement of native esophageal squamous epithelium (Sq) by columnar-intestinalized mucosa, and it is the main risk factor for Barrett-related adenocarcinoma (BAc).
Baffa, R, Bornschein, J, Braconi, C, Croce, CM, D'Angelo, E, Dall'Olmo, L, Fassan, M, Galasso, M, Gasparini, P, Nuovo, GJ, Pizzi, M, Realdon, S, Rugge, M, Souza, RF, Valeri, N, Vicentini, C, Volinia, S, Zaninotto, G   +17 more
core   +4 more sources