Results 241 to 250 of about 215,029 (331)

Intestinal mucosal barrier repair and immune regulation with an AI-developed gut-restricted PHD inhibitor. [PDF]

Nat Biotechnol
Fu Y, Ding X, Zhang M, Feng C, Yan Z, Wang F, Xu J, Lin X, Ding X, Wang L, Fan Y, Li T, Yin Y, Liang X, Xu C, Chen S, Pulous FE, Gennert D, Pun FW, Kamya P, Ren F, Aliper A, Zhavoronkov A.   +22 more
europepmc   +1 more source

Butyrate and mucosal inflammation: New scientific evidence supports clinical observation [PDF]

, 2015
Alvarado, David M., Ciorba, Matthew A., Cushing, Kelly   +2 more
core   +3 more sources

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Synergistic Enhancement of Modified‐PVDF Humidity Sensitivity via Chemical Adsorption‐Ionic Conductivity and its Application in Intelligent Powered Air‐Purifying Respirator

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The study developed a PVDF/SiO2 humidity sensor with superhydrophobic properties and integrated the humidity sensor into the intelligent powered air‐purifying respirator (IPAPR) for breath monitoring. Coupled with the Gated Recurrent Unit (GRU) machine learning prediction algorithm, it enables feedforward control of the fan to achieve respiratory ...
Xinjian He, Hongwei Liu, Xianjie Xu, Xinkai Qi, Danhong Gao, Hanling Deng, Dusong Hou, Qianyao Lu, Lei Zhu, Sheng Huang   +9 more
wiley   +1 more source

miR-155 induces sepsis-associated damage to the intestinal mucosal barrier via sirtuin 1/nuclear factor-κB-mediated intestinal pyroptosis. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Li Z, Wang Y, Huang W, Shi X, Ma T, Yu X.   +5 more
europepmc   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Pulsatilla Powder Ameliorates Damp-Heat Diarrhea in Piglets Through the Regulation of Intestinal Mucosal Barrier and the Pentose Phosphate Pathway Involving G6PD and NOX. [PDF]

Vet Sci
Qu Y, Ma Q, Wang C, Zhang L, Feng H, Lai S.   +5 more
europepmc   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Peptide RL‐QN15 Regulates Functions of Epidermal Stem Cells to Accelerate Skin Wound Regeneration via the FZD8/β‐Catenin Axis

Exploration, EarlyView.
Amphibian‐derived peptide RL‐QN15 activates the Wnt/β‐catenin signaling pathway by interacting with the FZD8 membrane receptor, promoting epidermal stem cells proliferation, migration, stemness, and EMT processes, thus promoting skin wound healing.
Yuansheng Li, Qiuye Jia, Naixin Liu, Saige Yin, Junyuan Wang, Yujing Ding, Yuliu Yang, Ying Peng, Zeqiong Ru, Shaoyang Zhang, Bu'er Qi, Jun Sun, Li He, Ying Wang, Kun Guo, Xinwang Yang   +15 more
wiley   +1 more source

Combined BPA and DIBP Exposure Induced Intestinal Mucosal Barrier Impairment Through the Notch Pathway and Gut Microbiota Dysbiosis in Mice. [PDF]

Foods
Duan M, Wang Y, Chen S, Lu J, Dong R, Yu Q, Xie J, Chen Y.   +7 more
europepmc   +1 more source