Results 71 to 80 of about 188,006 (344)

Diagnosis of pancreatic neoplasms using a novel method of DNA methylation analysis of mucin expression in pancreatic juice.

PLoS ONE, 2014
Mucins (MUC) play crucial roles in carcinogenesis and tumor invasion in pancreatic ductal adenocarcinoma (PDAC) and intraductal papillary mucinous neoplasms (IPMNs).
Seiya Yokoyama, Sho Kitamoto, Michiyo Higashi, Yuko Goto, Taro Hara, Dai Ikebe, Taketo Yamaguchi, Yoshifumi Arisaka, Toru Niihara, Hiroto Nishimata, Sadao Tanaka, Kyoichi Takaori, Surinder K Batra, Suguru Yonezawa   +13 more
doaj   +1 more source

Cowden syndrome - Diagnostic skin signs [PDF]

, 2001
Cowden syndrome is a rare autosomal dominant familial cancer syndrome with a high risk of breast cancer. The most important clinical features include carcinomas of the breast and thyroid, and hamartomatous polyps of the gastrointestinal tract.
Burgdorf, Walter H. C., Hildenbrand, C., Lautenschlager, Stephan   +2 more
core   +1 more source

What Causes Desmoplastic Reaction in Small Intestinal Neuroendocrine Neoplasms? [PDF]

, 2022
Gowri Ratnayake, Faidon‐Marios Laskaratos, Dalvinder Mandair, Martyn Caplin, Krista Rombouts, Christos Toumpanakis   +5 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Solitary plasmacytoma extramedullary to duodenal level: an unusual case of intestinal occlusion

Galicia Clínica, 2019
Plasma cell neoplasms represent only 1-2% of hematological malignancies and intestinal plasmocytoma represents only 3%. Extramedullary plasmocytomas most commonly are located in upper airway and oral cavity; the gastrointestinal plasmocytoma only ...
Manuel Lorenzo López Reboiro, Inés Navarro Menéndez, Lucía Cid Conde, José López Castro   +3 more
doaj   +1 more source

A Review of Colonoscopy in Intestinal Diseases

Diagnostics, 2023
Since the development of the fiberoptic colonoscope in the late 1960s, colonoscopy has been a useful tool to diagnose and treat various intestinal diseases.
Seung Min Hong, Dong Hoon Baek
doaj   +1 more source

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice [PDF]

, 2016
The FDA approved drug rapamycin increases lifespan in rodents and delays age-related dysfunction in rodents and humans. Nevertheless, important questions remain regarding the optimal dose, duration, and mechanisms of action in the context of healthy ...
Anderson, Anisimov, Atarashi, Augustine, Bates, Blackwell, Chen, Dai, de Oliveira, Ericsson, Ericsson, Flynn, Goldman, Halloran, Hard, Harrison, Hothorn, Johnson, Johnson, Johnson, Kaeberlein, Lamming, Majumder, Mannick, Mathew, Miller, Miller, Paulson, Prakash, Ramos, Treuting, Wilkinson, Xu, Zhang   +33 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Variants of gallbladder adenocarcinomas: Five case reports

Sahel Medical Journal, 2016
Conventional adenocarcinomas comprise of about 90% of all gallbladder neoplasms; among them, pancreatobiliary is the most common phenotype followed by intestinal and gastric foveolar types.
Subhajit Das, Debjit Banerjee, Soumit Mondal, Pankaj Tayal   +3 more
doaj   +1 more source

Benign TdT-positive cells in pediatric and adult lymph nodes: a potential diagnostic pitfall [PDF]

, 2018
Benign TdT-positive cells have been documented in a variety of non-hematopoietic tissues. Scant data are however available on their presence in non-neoplastic lymph nodes.
AGOSTINELLI, CLAUDIO, Bertuzzi, Clara, BRIGNOLA, STEFANO, Pillon, Marta, Pizzi, Marco, Righi, Simona, Rugge, Massimo, Sabattini, Elena, Semenzato, Gianpietro   +8 more
core   +1 more source