Results 1 to 10 of about 29,322 (305)

Standard: Human intestinal organoids [PDF]

open access: yesCell Regeneration, 2023
Organoids have attracted great interest for disease modelling, drug discovery and development, and tissue growth and homeostasis investigations. However, lack of standards for quality control has become a prominent obstacle to limit their translation ...
Yalong Wang   +25 more
doaj   +4 more sources

Current applications of intestinal organoids: a review [PDF]

open access: yesStem Cell Research & Therapy
In the past decade, intestinal organoid technology has paved the way for reproducing tissue or organ morphogenesis during intestinal physiological processes in vitro and studying the pathogenesis of various intestinal diseases.
Tao Xiang, Jie Wang, Hui Li
doaj   +4 more sources

Standard: Human intestinal cancer organoids

open access: yesCell Regeneration, 2023
Intestinal cancer is one of the most frequent and lethal types of cancer. Modeling intestinal cancer using organoids has emerged in the last decade.
Hanqing Lin   +25 more
doaj   +3 more sources

Intestinal organoids in farm animals [PDF]

open access: yesVeterinary Research, 2021
In livestock species, the monolayer of epithelial cells covering the digestive mucosa plays an essential role for nutrition and gut barrier function. However, research on farm animal intestinal epithelium has been hampered by the lack of appropriate in ...
Martin Beaumont   +6 more
doaj   +5 more sources

Fibroblasts enhance the growth and survival of adult feline small intestinal organoids [PDF]

open access: yesmSphere
Intestinal organoids are important cell culture models that complement live animal studies of many intestinal pathogens. Adult feline small intestinal organoids are needed for infectious disease research but are difficult to work with due to slow growth ...
Nicole D. Hryckowian   +5 more
doaj   +2 more sources

The application of intestinal organoids and their co-culture systems in the study of gastrointestinal diseases [PDF]

open access: yesOrganoid, 2022
The 3-dimensional culture of intestinal organoids provides insights into the phenotype and physiology of the intestine. Intestinal organoids comprise intestinal stem cells and differentiated intestinal epithelial cells; they can be stably cultured over ...
Panida Sittipo, Yun Kyung Lee
doaj   +1 more source

Establishment of intestinal organoids from small intestine of growing cattle (12 months old)

open access: yesJournal of Animal Science and Technology, 2022
Recently, we reported the robust in vitro three-dimensional (3D) expansion of intestinal organoids derived from adult bovine (> 24 months) samples. The present study aimed to establish an in vitro 3D system for the cultivation of intestinal organoids ...
Kang Won Park   +9 more
doaj   +1 more source

Effect of Wnt signaling pathway activation on the efficient generation of bovine intestinal organoids

open access: yesJournal of Animal Reproduction and Biotechnology, 2022
Recent progress has been made to establish intestinal organoids for an in vitro model as a potential alternative to an in vivo system in animals. We previously reported a reliable method for the isolation of intestinal crypts from the small intestine and
Kang Won Park   +6 more
doaj   +1 more source

Analogous comparison unravels heightened antiviral defense and boosted viral infection upon immunosuppression in bat organoids

open access: yesSignal Transduction and Targeted Therapy, 2022
Horseshoe bats host numerous SARS-related coronaviruses without overt disease signs. Bat intestinal organoids, a unique model of bat intestinal epithelium, allow direct comparison with human intestinal organoids.
Xiaojuan Liu   +14 more
doaj   +1 more source

Porcine Intestinal Apical-Out Organoid Model for Gut Function Study

open access: yesAnimals, 2022
Pig models provide valuable research information on farm animals, veterinary, and biomedical sciences. Experimental pig gut models are used in studies on physiology, nutrition, and diseases.
Sang-Seok Joo   +8 more
doaj   +1 more source

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