Results 31 to 40 of about 843,325 (293)

Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. [PDF]

, 2015
Oral absorption depends on many physiological, physiochemical and formulation factors. Two important properties that govern oral absorption are in vitro permeability and solubility, which are commonly used as indicators of human intestinal absorption ...
Newby, Danielle, Ghafourian, Taravat, Freitas, Alex. A., Danielle Newby (1695076), Alex A Freitas (16236734), Taravat Ghafourian (4466557), Freitas, Alex A.   +6 more
core   +1 more source

Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats

Nutrition & Metabolism, 2010
Background An increase in the intestinal permeability is considered to be associated with the inflammatory tone and development in the obesity and diabetes, however, the pathogenesis of the increase in the intestinal permeability is poorly understood ...
Suzuki Takuya, Hara Hiroshi
doaj   +1 more source

Intestinal barrier function and absorption in pigs after waeaning: a review [PDF]

, 2011
Under commercial conditions, weaning of piglets is associated with social, environmental and dietary stress. Consequently, small-intestinal barrier and absorptive functions deteriorate within a short time after weaning.
Wijtten, P.J.A., Verstegen, M.W.A., Meulen, J., van der   +2 more
core   +1 more source

Expanding the utility of the dextran sulfate sodium (DSS) mouse model to induce a clinically relevant loss of intestinal barrier function [PDF]

PeerJ, 2020
Background Inflammatory bowel disease (IBD) is a family of debilitating disorders that affects more than 1 million people in the United States. Many animal studies of IBD use a dextran sulfate sodium (DSS) mouse model of colitis that induces rapid and ...
Kyle E. Cochran, Nicholas G. Lamson, Kathryn A. Whitehead   +2 more
doaj   +2 more sources

Increasing weaning age of piglets from 4 to 7 weeks reduces stress, increases post-weaning feed intake but does not improve intestinal functionality [PDF]

, 2010
This study tested the hypothesis that late weaning and the availability of creep feed during the suckling period compared with early weaning, improves feed intake, decreases stress and improves the integrity of the intestinal tract.
Hoogendoorn, A., Dekker, R.A., Meulen, J., van der, Koopmans, S.J.   +3 more
core   +1 more source

The effects of micronutrient-fortified complementary/replacement food on intestinal permeability and systemic markers of inflammation among maternally HIV-exposed and unexposed Zambian infants. [PDF]

, 2011
The present randomised trial investigated the effects of feeding Zambian infants from 6 to 18 months old either a richly or basal micronutrient-fortified complementary/replacement food on gut integrity and systemic inflammation.
Chisenga, Molly, Mullen, Anne, Filteau, Suzanne, Anne Mullen, Molly Chisenga, Suzanne Filteau, Laura Gosset, Gosset, L, Chisenga, M, Gosset, Laura, Larke, Natasha, Filteau, S, Manno, Daniela, Kasonka, Lackson, Mullen, A, Larke, N, Kasonka, L, Manno, D, Lackson Kasonka, Natasha Larke, Daniela Manno   +20 more
core   +1 more source

Beta-blockers reduce intestinal permeability and early mortality following traumatic brain injury in Drosophila

microPublication Biology, 2021
Traumatic brain injury (TBI) frequently leads to non-neurological consequences such as intestinal permeability. The beta-blocker drug labetalol, which inhibits binding of catecholamine neurotransmitters to adrenergic receptors, reduces intestinal ...
Amanda R Scharenbrock, Rebeccah J Katzenberger, Megan C Fischer, Barry Ganetzky, David A Wassarman   +4 more
doaj   +1 more source

The Investigation of Nutritional Status, Intestinal Permeability, and Quality of Life in People with Celiac Disease

, 2022
BACKGROUND: Celiac disease is associated with impaired intestinal epithelial barrier integrity. Its consequences affect the nutritional status and quality of life of patients. This study aimed to determine nutritional status, intestinal permeability, and
Yeşim Öztekin, Öztekin, Yeşim, Özen Alahdab, Yeşim, Fatma Esra Güneş, Güneş, Fatma Esra, Yeşim Özen Alahdab   +5 more
core   +1 more source

The phenomenon of intestinal permeability and its association with cardiovascular disease. Current status

Кардиоваскулярная терапия и профилактика, 2020
Changes in the intestinal permeability in various pathologies are widely discussed in the scientific community. There is still no consensus on whether high intestinal permeability can lead to chronic noncommunicable diseases, but there is much evidence ...
D. A. Kashtanova, O. N. Tkacheva
doaj   +1 more source

Gastric and intestinal barrier impairment in tropical enteropathy and HIV: limited impact of micronutrient supplementation during a randomised controlled trial [PDF]

, 2010
Background Although micronutrient supplementation can reduce morbidity and mortality due to diarrhoea, nutritional influences on intestinal host defence are poorly understood.
Sanderson, IR, Sanderson Ian R, Shawa, T, Tamara Shawa, Shawa Tamara, Barclay G Robin, Stayner Mwanamakondo, G Robin Barclay, Ian R Sanderson, Soko Rose, Mwanamakondo Stayner, Kelly Paul, Mwanamakondo, S, Barclay, GR, Rose Soko, Paul Kelly, Geoff Smith, Smith Geoff, Soko, R, Smith, G, Kelly, P   +20 more
core   +2 more sources