STORM: a general model to determine the number and adaptive changes of epithelial stem cells in teleost, murine and human intestinal tracts. [PDF]
PLoS ONE, 2010 Intestinal stem cells play a pivotal role in the epithelial tissue renewal, homeostasis and cancer development. The lack of a general marker for intestinal stem cells across species has hampered analysis of stem cell number in different species and their
Zhengyuan Wang +2 more
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Effects of hormones on intestinal stem cells [PDF]
Stem Cell Research & Therapy, 2023 The maintenance of intestinal renewal and repair mainly depends on intestinal stem cells (ISCs), which can also contribute to the growth of intestinal tumours.
Li Liu +6 more
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The TMEM63B Channel Facilitates Intestinal Motility and Enhances Proliferation of Intestinal Stem Cells [PDF]
CellsThe intestines are in a constant state of motion and self-renewal. The mechanical breakdown of food facilitates intestinal movement and aids digestion.
Jing-Jing Tu +3 more
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Stem cells in the context of colon carcinogenesis (a literature review)
Zaporožskij Medicinskij Žurnal, 2023 Aim. To analyze the latest literature data on stem cells in general, intestinal stem cells in particular, as well as cancer stem cells in the context of colon carcinogenesis.
M. A. Shyshkin
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Plasticity of Paneth cells and their ability to regulate intestinal stem cells
Stem Cell Research & Therapy, 2020 Paneth cells (PCs) are located at the bottom of small intestinal crypts and play an important role in maintaining the stability of the intestinal tract.
Xianglin Mei, Ming Gu, Meiying Li
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IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration
Nature Communications, 2023 The influence of aging on intestinal stem cells and their niche can explain underlying causes for perturbation in their function observed during aging.
Omid Omrani +16 more
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Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. [PDF]
, 2017 Most differentiated cells convert glucose to pyruvate in the cytosol through glycolysis, followed by pyruvate oxidation in the mitochondria. These processes are linked by the mitochondrial pyruvate carrier (MPC), which is required for efficient ...
A Ootani +86 more
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Intestinal stem cell proliferation and epithelial homeostasis in the adult Drosophila midgut [PDF]
, 2015 Adult tissue homeostasis requires a tight balance between the removal of old or damaged cells and the production of new ones. Such processes are usually driven by dedicated stem cells that reside within specific tissue locations or niches.
Carroll, Lynsey +2 more
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Stem Cell Reports, 2014 LGR5 and BMI1 mark intestinal stem cells in crypt base columnar cells and +4 position cells, respectively, but characterization of functional markers in these cell populations is limited.
Ning Zhang +9 more
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Secretory Sorcery: Paneth Cell Control of Intestinal Repair and HomeostasisSummary
Cellular and Molecular Gastroenterology and Hepatology, 2021 Paneth cells are professional secretory cells that classically play a role in the innate immune system by secreting antimicrobial factors into the lumen to control enteric bacteria.
Paul Cray +2 more
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