Results 131 to 140 of about 2,142,587 (349)

Herpes simplex virus type 1 and 2 intracellular p40: type-specific and cross-reactive antigenic determinants on peptides generated by partial proteolysis [PDF]

, 1981
C J Heilman, M Zweig, Berge Hampar
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Intracellular mapping with SERS-encoded gold nanostars

, 2011
Laura Rodríguez‐Lorenzo, Željka Krpetić, Sílvia Barbosa, Ramón A. Álvarez‐Puebla, Luis M. Liz‐Marzán, Ian A. Prior, Mathias Brust   +6 more
openalex   +2 more sources

Regulating Intracellular Transport with External Stimuli [PDF]

, 2012
Anand Radhakrishnan, Artem K. Efremov, Michael Diehl   +2 more
openalex   +1 more source

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

Proceedings of the National Academy of Sciences of the United States of America, 1990
O. Thastrup, P. Cullen, B. Drøbak, M. Hanley, A. Dawson   +4 more
semanticscholar   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

The intracellular progesterone receptor regulates CD4+ T cells and T cell-dependent antibody responses

, 2013
Grant C. Hughes, Edward A. Clark, Alan H. M. Wong   +2 more
openalex   +2 more sources

Response: absence of CCR5 intracellular pools in most CD4 and CD8 T cells [PDF]

, 2011
Heather A. Pilch-Cooper, Scott F. Sieg, Thomas J. Hope, Valentina Mercanti, Robin E. Offord, Ronald S. Veazey, Donald E. Mosier, Brian Clagett, Julie K. Jadlowsky, Mark R. Chance, Ronald G. Collman, Nadeene E. Riddick, Oliver Hartley, Michael M. Lederman   +13 more
openalex   +1 more source

Structural Rearrangement of the Serotonin Transporter Intracellular Gate Induced by Thr276 Phosphorylation

, 2022
Matthew C. Chan, Erik Procko, Diwakar Shukla   +2 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source