Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles
Nanoparticle science is rapidly changing the landscape of various scientific fields and defining new technological platforms. This is perhaps even more evident in the field of nanomedicine whereby nanoparticles have been used as a tool for the treatment ...
Parisa Foroozandeh, A. Aziz
semanticscholar +1 more source
Effect of macromolecular crowding on the kinetics of glycolytic enzymes and the behaviour of glycolysis in yeast [PDF]
Water is involved in all aspects of biological activity, both as a solvent and as a reactant. It is hypothesized that intracellular water is in a highly structured state due to the high concentrations of macromolecules in the cell and that this may ...
Bagatolli, Luis Alberto +2 more
core +3 more sources
BIOMEDICAL POTENTIAL OF ALGO-BACTERIAL SYMBIOSES
The analysis of the latest published works on the interactions between microalgae and bacteria is presented. Microalgae as a result of multimillion evolution can interact with each other and with another microorganisms.
N. V. Nemtseva +2 more
doaj +1 more source
Mouse Syngeneic Melanoma Model with Human Epidermal Growth Factor Receptor Expression
The development of epidermal growth factor receptor (EGFR)-targeting agents for the treatment of malignant melanoma requires cheap and easy animal tumor models for high-throughput in vivo screening.
Tatiana A. Slastnikova +6 more
doaj +1 more source
Activation of the Listeria monocytogenes Virulence Program by a Reducing Environment. [PDF]
Upon entry into the host cell cytosol, the facultative intracellular pathogen Listeria monocytogenes coordinates the expression of numerous essential virulence factors by allosteric binding of glutathione (GSH) to the Crp-Fnr family transcriptional ...
Aaron T. Whiteley +5 more
core +2 more sources
Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus [PDF]
The treatment of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA) remains a challenge, partly due to localization of the bacteria inside the host’s cells, where antimicrobial penetration and efficacy is limited.
Chivu, A +3 more
core +3 more sources
Intracellular Staphylococcus aureus persisters upon antibiotic exposure
Bacterial persister cells are phenotypic variants that exhibit a transient non-growing state and antibiotic tolerance. Here, we provide in vitro evidence of Staphylococcus aureus persisters within infected host cells.
Frédéric Peyrusson +8 more
semanticscholar +1 more source
Identification of Fis1 Interactors in Toxoplasma gondii Reveals a Novel Protein Required for Peripheral Distribution of the Mitochondrion [PDF]
Toxoplasma gondii’s single mitochondrion is very dynamic and undergoes morphological changes throughout the parasite’s life cycle. During parasite division, the mitochondrion elongates, enters the daughter cells just prior to cytokinesis, and undergoes ...
Arrizabalaga, Gustavo +2 more
core +1 more source
In the inner mitochondrial membrane, several potassium channels that play a role in cell life and death have been identified. One of these channels is the ATP-regulated potassium channel (mitoKATP).
Milena Krajewska +3 more
doaj +1 more source
Intracellular sensing of viral genomes and viral evasion
During viral infection, virus-derived cytosolic nucleic acids are recognized by host intracellular specific sensors. The efficacy of this recognition system is crucial for triggering innate host defenses, which then stimulate more specific adaptive ...
Hyun-Cheol Lee +2 more
semanticscholar +1 more source

