Results 61 to 70 of about 2,142,587 (349)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

THE ROLE OF BIFIDOBACTERIA IN THE FORMATION OF HUMAN IMMUNE HOMEOSTASIS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2015
In the review the materials on the formation ofintestinal immune homeostasis through involvement of bifidobacteria which are the key species of microbiota of human colon biotype are presented.
O. V Bukharin, E. V Ivanova, N. B Perunova, I. N Chainikova   +3 more
doaj  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

INTRA-ERYTHROCYTE INVASION OF ESCHERICHIA COLI STRAINS WITH VARIOUS LEVELS OF ANTIHEMOGLOBIN ACTIVITY IN EXPERIMENT

Журнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Study of intra-erythrocyte invasion of Escherichia coli strains with various levels of antihemoglobin activity on a model of generalized infection. Materials and methods. Experiments were carried out on 72 male mice.
E. A Schuplova, S. B Fadeev, O. V Bukharin   +2 more
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Intracellular Pathogens: Host Immunity and Microbial Persistence Strategies

Journal of Immunological Research, 2019
Infectious diseases caused by pathogens including viruses, bacteria, fungi, and parasites are ranked as the second leading cause of death worldwide by the World Health Organization.
Aneesh Thakur, H. Mikkelsen, G. Jungersen   +2 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

EFFECT OF MICROSYMBIONTS ON THE ABILITY OF VAGINAL EPITHELIOCYTES TO MODIFY BIOLOGICAL PROPERTIES OF BACTERIA

Журнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Study regularities of effects of various types of vaginal microsymbionts on the ability of mucosal epitheliocytes of the vagina to modify biological properties of bacteria. Materials and methods.
E. A Kremleva, A. V Sgibnev, S. V Cherkasov   +2 more
doaj  

VAGINAL LACTOBACILLI REGULATE THE ACTIVITY OF MURAMIDASE VIA HYDROGEN PEROXIDE AND SURFACTANTS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. Evaluation of the effect of metabolites of vaginal lactobacilli on the enzymatic and bactericidal activity of muramidase. Materials and methods. We investigated how the enzymatic and bactericidal activity of muramidase changes after treatment with ...
A. V. Sgibnev, E. A. Kremleva
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source