Results 61 to 70 of about 3,092,750 (383)

The Obligate Intracellular Lifestyle [PDF]

Frontiers in Microbiology, 2011
Obligate intracellular bacteria represent consummate parasites, often covertly co-opting host resources to enable development and ultimately transmission to a new host. The overall success of this survival strategy is doubtless derived from co-evolution with respective eukaryotic hosts over hundreds of millions of years.
Fields, Kenneth A, Heinzen, Robert A, Carabeo, Rey   +2 more
openaire   +4 more sources

Intracellular transports and atherogenesis [PDF]

Frontiers in Bioscience, 2020
There is a great progress in understanding the cellular and molecular aspects of atherosclerosis, which is one of the leading causes of death. Yet, there are questions regarding the cellular and metabolic mechanisms that lead to atherogenesis. Among the many factors that influence this process, food plays a significant role.
Natalia R. Karelina, Irina S. Sesorova, Alexander A. Mironov, Ivan D. Dimov, Galina V. Beznoussenko   +4 more
openaire   +3 more sources

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

DETECTION OF POTENTIALLY PATHOGENIC BACTERIA IN THE BRACKISH RIVERS FLOWING INTO THE ELTON LAKE BY HIGH-THROUGHPUT SEQUENCING

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. To indicate potentially pathogenic bacteria in plankton of the brackish rivers flowing into the Elton Lake by high-throughput sequencing of 16S ssuRNA gene. Materials and methods. The water samples from brackish rivers Lantsug and Chernavka, flowing
E. A. Selivanova, Yu. A. Khlopko, N. E. Gogoleva, A. O. Plotnikov   +3 more
doaj   +1 more source

Swedish isolates of Vibrio cholerae enhance their survival when interacted intracellularly with Acanthamoeba castellanii [PDF]

Infection Ecology & Epidemiology, 2016
Vibrio cholerae is a Gram-negative bacterium that occurs naturally in aquatic environment. Only V. cholerae O1 and V. cholerae O139 produce cholera toxin and cause cholera, other serogroups can cause gastroenteritis, open wounds infection, and ...
Salah Shanan, Magdi Bayoumi, Amir Saeed, Gunnar Sandström, Hadi Abd   +4 more
doaj   +1 more source

Bone and Joint Infection Involving Corynebacterium spp.: From Clinical Features to Pathophysiological Pathways

Frontiers in Medicine, 2021
Introduction: Corynebacteria represent often-neglected etiological agents of post-traumatic and/or post-operative bone and joint infection (BJI). We describe here clinical characteristics and bacteriological determinants of this condition.Methods: A ...
Pierre Chauvelot, Pierre Chauvelot, Pierre Chauvelot, Tristan Ferry, Tristan Ferry, Tristan Ferry, Virginie Tafani, Alan Diot, Jason Tasse, Jason Tasse, Anne Conrad, Anne Conrad, Anne Conrad, Christian Chidiac, Christian Chidiac, Christian Chidiac, Evelyne Braun, Evelyne Braun, Sébastien Lustig, Sébastien Lustig, Frédéric Laurent, Frédéric Laurent, Frédéric Laurent, Florent Valour, Florent Valour, Florent Valour   +25 more
doaj   +1 more source

Determination of intracellular nitrate [PDF]

Biochemical Journal, 1989
A sensitive procedure has been developed for the determination of intracellular nitrate. The method includes: (i) preparation of cell lysates in 2 M-H3PO4 after separation of cells from the outer medium by rapid centrifugation through a layer of silicone oil, and (ii) subsequent nitrate analysis by ion-exchange h.p.l.c.
García Guerrero, Miguel, Lara Coronado, Catalina, Romero Rodríguez, José María   +2 more
openaire   +4 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids. [PDF]

, 2016
The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood.
Currais, Antonio, Daugherty, Daniel, M Armando, Aaron, Maher, Pam, Quehenberger, Oswald, Schubert, David   +5 more
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source