Results 61 to 70 of about 3,033,431 (331)
Alternate routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4 [PDF]
, 2015 Insulin-stimulated delivery of glucose transporters (GLUT4) from specialized intracellular GLUT4 storage vesicles (GSVs) to the surface of fat and muscle cells is central to whole-body glucose.
Bryant, Nia J. +3 more
core +3 more sources
Intracellular Pathogens: Host Immunity and Microbial Persistence Strategies
Journal of Immunological Research, 2019 Infectious diseases caused by pathogens including viruses, bacteria, fungi, and parasites are ranked as the second leading cause of death worldwide by the World Health Organization.
Aneesh Thakur +2 more
semanticscholar +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Modulation of a sustained calcium current by intracellular pH in horizontal cells of fish retina. [PDF]
, 1993 A sustained high voltage-activated (HVA), nifedipine- and cadmium-sensitive calcium current and a sustained calcium action potential (AP) were recorded from horizontal cells isolated from catfish retina.
Copenhagen, DR, Dixon, DB, Takahashi, K
core
Geometry based dynamic modeling of the neuron-electrode interface [PDF]
, 2000 A dynamic model of the neuron-electrode interface is presented which is based on the interface geometry and the electrical properties of the neuronal membrane. The model is used to compute the potential at the electrode and the local membrane potentials.
Buitenweg, J.R. +2 more
core +3 more sources
Nanogels with Selective Intracellular Reactivity for Intracellular Tracking and Delivery
Chemistry – A European Journal, 2020 AbstractA multimodal approach for hydrogel‐based nanoparticles was developed to selectively allow molecular conjugated species to either be released inside the cell or remain connected to the polymer network. Using the intrinsic difference in reactivity between esters and amides, nanogels with an amide‐conjugated dye could be tracked intracellularly ...
Guangyue Zu +5 more
openaire +3 more sources
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
A P-type ATPase importer that discriminates between essential and toxic transition metals [PDF]
, 2009 Transition metals, although being essential cofactors in many physiological processes, are toxic at elevated concentrations. Among the membrane-embedded transport proteins that maintain appropriate intracellular levels of transition metals are ATP-driven
A. T. Lee +25 more
core +2 more sources
Intracellular Protein Topogenesis [PDF]
Proceedings of the National Academy of Sciences, 1980 Concurrently with or shortly after their synthesis on ribosomes, numerous specific proteins are unidirectionally translocated across or asymmetrically integrated into distinct cellular membranes.
openaire +4 more sources
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source