Results 211 to 220 of about 520,227 (253)

Genetic Defects of Intracellular-Membrane Transport

New England Journal of Medicine, 2000
The compartmentalization of functions into distinct membrane-bound organelles is a central characteristic of cells. The protein and lipid composition of these organelles is unique, a factor that is vital for their proper function. This necessitates tightly controlled transport of biomolecules from their sites of synthesis or uptake to specific ...
V M, Olkkonen, E, Ikonen
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The Network of Intracellular Membranes

Hospital Practice, 1973
If the external membrane organizes the cell as a unit, the internal membranes make possible the differentiation of activities within the cell, greatly increasing its working surface. An overview of the membranes that define the organelles within the cell sap notes they are structurally of two types, relates structure to function, and describes the ...
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Specific localization of Rabs at intracellular membranes

Biochemical Society Transactions, 2012
Despite over two decades of research, the mechanism of Rab targeting to specific intracellular membranes is still not completely understood. Present evidence suggests that the original hypothesis that the message for targeting resides solely in the hypervariable C-terminus is incorrect, and a second mechanism involving a GDF [GDI (guanine-nucleotide ...
Blümer, J., Wu, Y., Goody, R., Itzen, A.   +3 more
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CD95 ligation and intracellular membrane flow

Biochemical Journal, 2008
Whereas ligation of the CD95 death receptor in the plasma membrane of so-called type I cells leads to a direct caspase 8-dependent activation of downstream effector caspases, mitochondrial amplification of caspase 8-derived signals is required in so-called type II cells in order to execute apoptotic cell death.
Roland, Reinehr, Dieter, Häussinger
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Intracellular trafficking of lysosomal membrane proteins

BioEssays, 1996
AbstractLysosomes are the site of degradation of obsolete intracellular material during autophagy and of extracellular macromolecules following endocytosis and phagocytosis. The membrane of lysosomes and late endosomes is enriched in highly glycosylated transmembrane proteins of largely unknown function.
Hunziker W, Geuze HJ
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Intracellular Parcel Service: Current Issues in Intracellular Membrane Trafficking

2014
Eukaryotic cells contain a multitude of membrane structures that are connected through a highly dynamic and complex exchange of their constituents. The vibrant instability of these structures challenges the classical view of defined, static compartments that are connected by different types of vesicles. Despite this astonishing complexity, proteins and
Herrmann, J. M., Spang, A.
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Effect of taurine on a muscle intracellular membrane

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1973
Abstract Sarcoplasmic reticulum from rat skeletal muscle had rates of calcium oxalate uptake dependent upon the speed with which the muscle was removed and homogenized. Rapidly isolated sarcoplasmic reticulum (muscle removed and homogenized within 20 min) showed a 25% increase in rate of calcium oxlate uptake in the presence of 15 mM taurine, and the
R, Huxtable, R, Bressler
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Intracellular Membrane Fusion

2009
Fusion of biological membranes plays an important role in cell structure and function. It is essential for organelle biogenesis, vesicle targeting, constitutive and regulated exocytosis, endocytosis, pathogen invasion of host cells, sperm-egg fusion and skeletal muscle formation.
Dalu Xu, Jesse C. Hay
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Coat proteins in intracellular membrane transport

Current Opinion in Cell Biology, 1994
Transport of newly synthesized material from the endoplasmic reticulum (ER) towards the Golgi complex, through the Golgi cisternae, and out of the trans-Golgi network (TGN) is thought to be mediated by vesicular carriers. Different types of vesicle are involved in this biosynthetic membrane traffic.
Kreis TE, Pepperkok R
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Intracellular ATP and Cardiac Membrane Currents

1988
Energy metabolism has a strong influence on the electrical activities of cardiac muscle (Trautwein et al., 1954; De Mello, 1959; MacLeod and Daniel, 1965; for review see Carmeliet, 1978). When cardiac muscle is exposed to anoxic conditions or metabolic inhibitors, or is depleted of substrates, the plateau of the action potential is depressed in the ...
A, Noma, T, Shibasaki
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