Results 101 to 110 of about 1,012,172 (301)

Vimentin in Bacterial Infections

Cells, 2016
Despite well-studied bacterial strategies to target actin to subvert the host cell cytoskeleton, thus promoting bacterial survival, replication, and dissemination, relatively little is known about the bacterial interaction with other components of the ...
Tim N. Mak, Holger Brüggemann
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The tomato Prf complex is a molecular trap for bacterial effectors based on Pto transphosphorylation [PDF]

, 2013
The bacteria Pseudomonas syringae is a pathogen of many crop species and one of the model pathogens for studying plant and bacterial arms race coevolution.
John P Rathjen, Rathjen, John P, Alexi L. Balmuth, Vardis Ntoukakis, Balmuth, Alexi L, Balmuth, Alexi L., Ra M. E. Jones, Tatiana S Mucyn, Gutierrez, Jose R., Jose R. Gutierrez, Mucyn, Tatiana S, Alexi L. Balmuth, Vardis Ntoukakis (223009), Ntoukakis Vardis, Jose R. Gutierrez (278825), Ntoukakis, Vardis, Alexi L. Balmuth (215165), John P. Rathjen (232061), Jose R Gutierrez, Gutierrez, Jose R, Balmuth Alexi L., Vardis Ntoukakis, Jones, Alexandra M., Tatiana S. Mucyn (278824), Jones, Alexandra M. E, Tatiana S. Mucyn¤a, Rathjen John P., Rathjen, John P., Alexi L Balmuth, Jones Alexandra M. E., Mucyn, Tatiana S., John P. Rathjen*¤b, Alexandra M. E. Jones, Gutierrez Jose R., John P. Rathjen, Alexandra M. E. Jones (50010), Tatiana S. Mucyn, Alexandra M E Jones, Mucyn Tatiana S.   +38 more
core   +2 more sources

Ironing Out the Unconventional Mechanisms of Iron Acquisition and Gene Regulation in Chlamydia

Frontiers in Cellular and Infection Microbiology, 2017
The obligate intracellular pathogen Chlamydia trachomatis, along with its close species relatives, is known to be strictly dependent upon the availability of iron.
Nick D. Pokorzynski, Christopher C. Thompson, Rey A. Carabeo   +2 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Immunity to Intracellular Salmonella Depends on Surface-associated Antigens [PDF]

, 2012
Invasive Salmonella infection is an important health problem that is worsening because of rising antimicrobial resistance and changing Salmonella serovar spectrum.
Rizos Konstantin, Beatrice Claudi (126116), Dirk Bumann (126124), Dirk Bumann, Somedutta Barat (126107), Barat, Somedutta, Rizos, K., Bumann, D., Schemmer, Anne K, Claudi Beatrice, Neil Burton (126123), Anne K Schemmer, Barat Somedutta, Dennis Kirchhoff (126121), Somedutta Barat, Alexander Schmidt (68515), Kirchhoff, D., Alain Mazé, Willer, Yvonne, Anne K. Schemmer (126119), Kirchhoff Dennis, Rizos, Konstantin, Dennis Kirchhoff, Bumann, Dirk, Burton Neil, Schemmer, A., Claudi, B., Mazé, Alain, Schmidt Alexander, Schemmer Anne K., Yvonne Willer (126110), Konstantin Rizos (126113), Willer Yvonne, Yvonne Willer, Willer, Y., Burton, Neil, Bumann Dirk, Alexander Schmidt, Mazé Alain, Beatrice Claudi, Schmidt, A., Alain Mazé (126117), Mazé, A., Claudi, Beatrice, Kirchhoff, Dennis, Barat, S., Konstantin Rizos, Burton, N., Schemmer, Anne K., Schmidt, Alexander, Neil Burton   +50 more
core   +2 more sources

Gasdermins against intracellular bacterial pathogens

Nature Microbiology
Intracellular bacterial pathogens can cause high levels of morbidity and mortality in humans. Host immune responses that protect against these infections include pyroptosis, a form of lytic cell death caused by the insertion of large gasdermin (GSDM) pores into the host plasma membrane.
Fernando W. Souza, Yaxin Liu, Jacqueline Trujillo, Edward A. Miao   +3 more
openaire   +2 more sources

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Plants for planting; indirect evidence for the movement of a serious forest pathogen, Teratosphaeria destructans, in Asia [PDF]

, 2011
Fungal diseases caused by native pathogens and pathogens introduced with planting stock have a significant impact on exotic plantation forestry in the tropics.
Wingfield, Michael J., Treena Burgess, Burgess, Treena I., Vera Andjic, Giles Hardy, Bernard Dell, Wingfield, M., Hardy, G., Paul Barber, Andjic, V., Barber, Paul A., Hardy, Giles E. St. J., Dell, Bernard (Bernie), Barber, P., Andjic, Vera, Dell, B., Michael Wingfield, Burgess, T.   +17 more
core   +1 more source

Stage-Specific and Selective Delivery of Caged Azidosugars into the Intracellular Parasite Toxoplasma gondii by Using an Esterase-Ester Pair Technique

mSphere, 2019
Toxoplasma gondii is an obligate intracellular parasite that chronically infects up to a third of the human population. The parasites persist in the form of cysts in the central nervous system and serve as a reservoir for the reactivation of toxoplasmic ...
Tadakimi Tomita, Hua Wang, Peng Wu, Louis M. Weiss   +3 more
doaj   +1 more source