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Nanocarriers with Gentamicin to Treat Intracellular Pathogens
Journal of Nanoscience and Nanotechnology, 2006Brucellosis is a worldwide zoonosis caused by different species of the genus Brucella. The intracellular localisation of this pathogen, particularly in macrophages, renders treatment difficult since most antibiotics known to be efficient in vitro do not actively pass through cellular membranes.
C, Lecaroz +2 more
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Phenotypic modulation by intracellular bacterial pathogens
Electrophoresis, 1999Microorganisms have the capacity to sense their environment and to respond to it by alteration in gene expression and protein synthesis. Two-dimensional electrophoresis (2-DE) provides a powerful tool to examine the global response in bacterial protein synthesis upon exposure to different environmental signals.
Y A, Kwaik, O S, Harb
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Is Salmonella an Intracellular Pathogen?
1993My assigned topic of presentation in this Workshop is to address the issue of whether Salmonella is an intracellular pathogen. The simple answer to that question is yes and no, depending on the host cells into which the pathogen has entered. There are many of us here in this Workshop who are studying the genetic factors governing the invasive or ...
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Autophagy as a defence against intracellular pathogens
Essays in Biochemistry, 2013Autophagy is a membrane trafficking pathway that results in the formation of autophagosomes which deliver portions of the cytosol to lysosomes for degradation. When autophagosomes engulf intracellular pathogens, the pathway is called ‘xenophagy’ because it leads to the removal of foreign material.
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Vaccines against intracellular bacterial pathogens
Drug Discovery Today, 2008There is a long history of remarkable success in developing vaccines against bacteria that are extracellular pathogens. In general, the development of vaccines against intracellular bacterial pathogens has proven to be more challenging. Typically, such vaccines need to induce a range of immune responses, including antibody, CD4(+) and CD8(+) T cell ...
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Remodeling Schemes of Intracellular Pathogens
Science, 1994P L, Small, L, Ramakrishnan, S, Falkow
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Proceedings of the National Academy of Sciences of the United States of America, 2020
Robert Luallen +2 more
exaly
Robert Luallen +2 more
exaly