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Advanced Healthcare Materials, EarlyView.Organelle localization‐induced biorthogonal polymerization enables direct synthesis of photostable poly‐AIEgens within targeted organelles for super‐resolution live‐cell imaging. ABSTRACT Real‐time monitoring of dynamic biological processes demands fluorescent probes that can withstand prolonged light exposure without photobleaching—a critical ...
Gaeun Park +4 more
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Advanced Healthcare Materials, EarlyView.Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum +5 more
wiley +1 more source
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Mechanisms of intracellular protein transport
Nature, 1994Recent advances have uncovered the general protein apparatus used by all eukaryotes for intracellular transport, including secretion and endocytosis, and for triggered exocytosis of hormones and neurotransmitters. Membranes are shaped into vesicles by cytoplasmic coats which then dissociate upon GTP hydrolysis.
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Intracellular cholesterol transport
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1999The intracellular movement of cholesterol in mam- malian cells may involve complex pathways by which the sterol moves to various cellular sites and mediates transcriptional regu- lation, enzyme activation, and protein degradation. Current evidence indicates that there are three distinct pathways modulating intracellular cholesterol trafficking.
L, Liscum, N J, Munn
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Intracellular transport of lipids
Molecular and Cellular Biochemistry, 1989Translocation of lipids inside mammalian cells is considered to be facilitated by a number of low-molecular weight lipid binding proteins. An overview of these proteins is given, with particular reference to the heart. Three distinct phospholipid transfer proteins specifically stimulate the net transfer of individual phospholipid classes between ...
J F, Glatz, G J, van der Vusse
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Monitoring intracellular transport
Journal of Theoretical Biology, 1975Abstract Ingested plastic scintillator spheres are shown to be a useful tool for investigating intracellular transport of material labelled by a weak beta emitter. It is found that-by numerically solving a linear integral equation with known kernel-the time evolution of the intracellular emitter density profile in the vicinity of the cell membrane is
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Intracellular transport of Alphaherpesvirinae
Virologie, 2020The Alphaherpesvirinae sub-family includes viruses primarily associated with cold sores, genital herpes, chicken pox and shingles in humans, but are responsible for several other pathologies and additionally infect many animals. These viruses are large entities that travel through various cellular compartments during their life cycle.
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Intracellular transport of bile acids
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2000Bile acids originate from the liver and are transported via bile to the intestines where they perform an important role in the absorption of lipids and lipid-soluble nutrients. Most of the bile acids are reclaimed from the terminal ileum and returned to the liver via portal blood for reuse.
L B, Agellon, E C, Torchia
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Intracellular Lipid Transport In Eukaryotes
Annual Review of Physiology, 1987The metabolic regulation and biological significance of the large number of lipid species found in all biological membranes are not well understood. It has been estimated that there are greater than 1000 chemically distinct phospho lipid species in eukaryotic cells (98), all of which must bestow significant evolutionary advantages to the cells.
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pH-induced intracellular protein transport
Physical Biology, 2006A new mechanism of selective transport and localization of proteins inside any living cell is presented. The mechanism is based on pH-induced protein trapping. It is shown that spontaneous and unique spatial redistribution of different proteins is possible in any aqueous solution with stable non-uniform distribution of H(+) ions.
E M, Baskin +2 more
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