Results 71 to 80 of about 803,683 (201)

The transporter-like protein inebriated mediates hyperosmotic stimuli through intracellular signaling [PDF]

, 2000
We cloned the inebriated homologue MasIne from Manduca sexta and expressed it in Xenopus laevis oocytes. MasIne is homologous to neurotransmitter transporters but no transport was observed with a number of putative substrates.
Chiu, Chi-Sung, Cohen, Bruce N., Gill, Sarjeet S., Lester, Henry A., Ross, Linda S.   +4 more
core  

Barcoding Hedgehog for Intracellular Transport [PDF]

Science Signaling, 2011
Cholesterol modification may alter the intracellular localization of Hedgehog, thereby influencing where Hedgehog is released.
openaire   +2 more sources

Epidermal T Cell Dendrites Serve as Conduits for Bidirectional Trafficking of Granular Cargo

Frontiers in Immunology, 2018
Dendritic epidermal T cells (DETCs) represent a prototypical lineage of intraepithelial γδ T cells that participate in the maintenance of body barrier homeostasis.
Grzegorz Chodaczek, Grzegorz Chodaczek, Monika Toporkiewicz, M. Anna Zal, Tomasz Zal   +4 more
doaj   +1 more source

The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus [PDF]

, 2010
Expansion of a polyglutamine (polyQ) tract in the Huntingtin (Htt) protein causes Huntington's disease (HD), a fatal inherited neurodegenerative disorder.
Baquet, Bates, Bennett, Bhakar, Blahos, Caviston, Chen, Cho, Colin, Colomer, Dragatsis, Dunkley, Edoardo Marcora, Engelender, Fagerlund, Fridmacher, Gauthier, Graham, Gray, Gutekunst, Hanz, Harkiolaki, Hayden, Hering, Hickey, Hunt, Imarisio, Jordan, Joshi, Kaltschmidt, Kaltschmidt, Kaltschmidt, Kennedy, Korkin, Kornau, Leavitt, Leavitt, Li, Li, Li, Lipsky, Ma, Marcora, Marini, Marini, Mary B. Kennedy, Mattson, Meffert, Meffert, Menalled, Mikenberg, Mosammaparast, Otis, Patterson, Perlson, Shimojo, Simmons, Song, Strand, Sun, Suzuki, Takano, The Huntington's Disease Collaborative Research Group, Thompson, Tian, Towbin, Trushina, Velier, Wang, Wellmann, Xie, Zhang, Zuccato, Zuccato, Zuccato   +74 more
core   +4 more sources

Spatiotemporal visualization of subcellular dynamics of carbon nanotubes [PDF]

, 2012
To date, there is no consensus on the relationship between the physicochemical characteristics of carbon nanotubes (CNTs) and their biological behavior; however, there is growing evidence that the versatile characteristics make their biological fate ...
Baba, Yoshinobu, Bianco, Alberto, Braeckmans, Kevin, Habuchi, Satoshi, Kaji, Noritada, Serag, Maged F   +5 more
core   +3 more sources

Transcriptional regulation of the ABCC6 gene and the background of impaired function of missense disease-causing mutations. [PDF]

, 2013
The human ATP-binding cassette family C member 6 (ABCC6) gene encodes an ABC transporter protein expressed primarily in the liver and to a lesser extent in the kidneys and the intestines.
Arányi, Tamás, Bacquet, Caroline, Boussac, Hugues de, Fülöp, Krisztina, Pomozi, Viola, Váradi, András   +5 more
core   +1 more source

Acid transport by intracellular vesicles [PDF]

Journal of Internal Medicine, 1990
Abstract. Many intracellular organelles contain a unique primary, electrogenic proton pump termed the vacuolar H+‐ATPase. This pump, found in many endocytic, secretory, and storage vesicles in fungal, plant and animal cells, functions, in conjunction with a chloride conductance, to acidify the vesicle interior.
openaire   +3 more sources

Subcellular localization of microsomal triglyceride transfer protein

Journal of Lipid Research, 2003
Microsomal triglyceride transfer protein (MTP) is essential for the assembly of apolipoprotein B-containing lipoproteins. Within the endoplasmic reticulum, it transfers lipid from the membrane to the forming lipoprotein.
Larry L. Swift, Mei-Ying Zhu, Bharati Kakkad, Aneta Jovanovska, M. Diana Neely, Klara Valyi-Nagy, Richard L. Roberts, David E. Ong, W. Gray Jerome   +8 more
doaj   +1 more source

Hook3 is a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and KIF1C. [PDF]

, 2019
The unidirectional and opposite-polarity microtubule-based motors, dynein and kinesin, drive long-distance intracellular cargo transport. Cellular observations suggest that opposite-polarity motors may be coupled.
Dickey, Andrea M, Dzieciatkowska, Monika, Harper, J Wade, Kendrick, Agnieszka A, Reck-Peterson, Samara L, Redwine, William B, Tran, Phuoc Tien, Vaites, Laura Pontano   +7 more
core  

The 50-nm Free Vesicles Visible in Saccharomyces cerevisiae Are Not COPII-Dependent

Current Issues in Molecular Biology
According to the current dogma, ER–Golgi transport is mediated by COPII-coated vesicles. However, numerous contradictions have emerged in this field. In this study, we demonstrate that Saccharomyces cerevisiae contains three distinct types of membrane ...
Alexander A. Mironov, Aurora Fusella, Galina V. Beznoussenko   +2 more
doaj   +1 more source