Results 111 to 120 of about 1,288,434 (306)

Transportation and Tourism [PDF]

open access: yes
DTRT06-G-0044This project explored the link between transportation and tourism in Texas. A session on transit and tourism was organized and conducted as part of the 2012 Texas Transit Conference.
Turnbull, Katherine F.   +2 more
core  

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Investing in transportation to keep Texas economically competitive [PDF]

open access: yes
This current report, It's About Time: Investing in Transportation to Keep TexasEconomically Competitive, updates the February 2009 report by providingan enhanced analysis of the current state of the Texas transportation system,determining the household ...
Texas. Transportation Commission
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Midwest Transportation Consortium : 2009-2010 annual report. [PDF]

open access: yes
In October 2009, the Midwest Transportation Consortium (MTC) began its third yearas a Tier I University Transportation Center (UTC). Its theme, \u201cTransportation Safetythrough Improvements in Management Information Systems,\u201d reflects our ...
Midwest Transportation Consortium
core  

Maritime trade and transportation '99

open access: yes
The marine transportation system contributes to U.S. economic growth, enhances global competitiveness, and supports national security objectives.
United States. Department of Transportation. Bureau of Transportation Statistics
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

The transportation economy : just in time. [PDF]

open access: yes
DTRT06-G-0044The purpose of this project was to produce a short educational video, targeted at middle school and high school students, illustrating the critical role transportation plays in our modern economy.
Cole, Richard   +2 more
core  

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