The study on the transport and phosphorylation kinetics of zidovudine in the Chinese population and its significance for individualized antiretroviral therapy. [PDF]
Sci RepTang F, Ji S, Lai X, Yan T, Peng J.
europepmc +1 more source
Pilot information system for cross-border hazmat transportation. [PDF]
DTRT07-G-0006Under NAFTA requirements, all hazardous materials that are shipped into Mexico or generated during themanufacturing process must be shipped back to its point of origin, typically the United States.
Texas Transportation Institute. Center for International Intelligent Transportation Research
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FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Expression, Localization and Actions of Galectin-3: Implications in the Pathophysiology and Therapy of Cardiovascular Disease. [PDF]
Int J Mol SciDu XJ, She G, Pang ZD, Zhang Y, Deng XL.
europepmc +1 more source
Midwest Transportation Consortium annual progress report : October 2000. [PDF]
From the Director: The Midwest Transportation Consortium (MTC), the University Transportation Center serving the statesof Iowa, Kansas, Missouri, and Nebraska, had a very successful first year of operation.
Midwest Transportation Consortium
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MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
A multi-omics systems toxicology framework reveals amino acid-mediated stress adaptation to deltamethrin exposure in a yeast model. [PDF]
Sci RepYavuz M +5 more
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Insights Into Aggregation-Delayed Phenotype of Dictyostelium discoideum. [PDF]
Cell Biol IntAlamer SA.
europepmc +1 more source