Results 181 to 190 of about 1,288,434 (306)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Vibration frequency drives oxidative membrane damage and metabolic remodeling underlying muscle quality deterioration in yellow catfish (<i>Pelteobagrus fulvidraco</i>) under waterless transport. [PDF]

Food Chem X
Huang G, Liao T, Wang Z, Li Y, Qiu L, Wang L, Bai C.   +6 more
europepmc   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

HSP47 in Mitochondria: Roles in Apoptosis, Signal Transduction, and Protein and Virus Transportation. [PDF]

Cells
Surinkaew S, Hosoya N, Ito H, Abe H, Nakanishi I, Matsumoto KI, Imai M, Kawakami F, Kubo M, Ichikawa T, Ichikawa H, Yonei Y, Beppu HJ, Suka J, Boonhok R, Chatatikun M, Sukati S, Piya-Amornphan N, Rungruangbaiyok C, Lektip C, Somsak V, Chaiswing L, Sompol P, Urano J, Moi ML, Takayanagi H, Indo HP, Majima HJ.   +27 more
europepmc   +1 more source

A guide to transportation funding options : a web site development project, final report, June 30, 2008.

DTRT06-G-0044As our nation\u2019s transportation demand continues to grow due to population increases and an expandedeconomy, elected officials at all levels of government are faced with difficult decisions regardingmechanisms to adequately fund the ...
Texas Transportation Institute. University Transportation Center for Mobility, Geiselbrecht, Tina   +1 more
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Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Mesenchymal stem cell senescence as a potency brake: causes, consequences, and cures. [PDF]

Front Aging
Zhou S, Xie Y, Guo Y, Zhang Y, Liu Y.
europepmc   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Microplastics and Nanoplastics as Potential Metabolic Disruptors: Implications for Insulin Resistance and Type 2 Diabetes. [PDF]

Toxics
Cornelli U, Casella C.
europepmc   +1 more source

Midwest Transportation Consortium annual progress report : October 2002.

From the Director: For the past three years, the Midwest Transportation Consortium (MTC) has focused its efforts insupporting the development and use of asset management systems in transportation. The MTC\u2019s mainfocus is on human capital development\
Midwest Transportation Consortium
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