A computational model that predicts behavioral sensitivity to intracortical microstimulation. [PDF]
J Neural Eng, 2017 Intracortical microstimulation (ICMS) is a powerful tool to investigate the neural mechanisms of perception and can be used to restore sensation for patients who have lost it. While sensitivity to ICMS has previously been characterized, no systematic framework has been developed to summarize the detectability of individual ICMS pulse trains or the ...
Kim S, Callier T, Bensmaia SJ.
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Optical imaging of cortical networks via intracortical microstimulation.
J Neurophysiol, 2013 Understanding cortical organization is key to understanding brain function. Distinct neural networks underlie the functional organization of the cerebral cortex; however, little is known about how different nodes in the cortical network interact during perceptual processing and motor behavior. To study cortical network function we examined whether the
Brock AA, Friedman RM, Fan RH, Roe AW.
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Brain StimulationBackground: Intracortical microstimulation (ICMS) of the somatosensory cortex activates neurons around the stimulating electrodes and can elicit tactile sensations. Objective: It is not clear how the direct activation of cortical neurons influences their
Luke E. Osborn +15 more
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Behavioral assessment of sensitivity to intracortical microstimulation of primate somatosensory cortex. [PDF]
Proc Natl Acad Sci U S A, 2015 Significance Electrical stimulation of sensory structures in the brain is a powerful tool to investigate neural circuits and may provide a means to restore sensation for patients for whom stimulation of the nerve is not an option. For both purposes, however, it is critical to understand how the design of the stimulation shapes the evoked ...
Kim S +5 more
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Potential role of noise to improve intracortical microstimulation in tactile neuroprostheses
Neural Regeneration Research, 2021 Pedro Mabil +3 more
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A Machine Learning-Based Decoder Framework for the Cortical Voltage-Sensitive Dye Responses to Retinal Neuromorphic Microstimulation: A Proof-of-Concept Simulation Study [PDF]
BioengineeringIntracortical microstimulation (ICMS) is a promising approach for visual prostheses. We recently proposed using retinal neuromorphic spike trains derived from visual images as ICMS pulse sequences, and preliminarily recorded cortical voltage-sensitive ...
Keisuke Yamada +3 more
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Optimal interphase delay in biphasic current pulses facilitates neural circuit activation induced by microstimulation in the mouse visual cortex [PDF]
Frontiers in NeuroscienceCathodic-first biphasic current pulses are commonly employed in intracortical microstimulation. Due to the intricate arrangement of axons, somata, and dendrites in the cerebral cortex, membrane polarizations induced by the cathodic and subsequent anodic ...
Santa Fukuda, Yuki Hayashida
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Leveraging computational models to understand mechanisms of intracortical microstimulation
Brain Stimulation, 2023 Warren Grill +3 more
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Brain Stimulation, 2021 Background: Previous studies have shown that neurons of the cerebral cortex can be injured by implantation of, and stimulation with, implanted microelectrodes.
Douglas McCreery +3 more
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Equalization for intracortical microstimulation artifact reduction [PDF]
2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2013 We present a method for decreasing the duration of artifacts present during intra-cortical microstimulation (ICMS) recordings by using techniques developed for digital communications. We replace the traditional monophasic or biphasic current stimulation pulse with a patterned pulse stream produced by a Zero Forcing Equalizer (ZFE) filter after ...
Chu, Philip +5 more
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