A brain-machine interface instructed by direct intracortical microstimulation [PDF]
Frontiers in Integrative Neuroscience, 2009 Brain-machine interfaces (BMIs) establish direct communications between the brain and artificial actuators. As such, they hold considerable promise for restoring mobility and communication in patients suffering from severe body paralysis. To achieve this
Joseph E O'Doherty +14 more
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Proprioceptive and cutaneous sensations in humans elicited by intracortical microstimulation [PDF]
eLife, 2018 Pioneering work with nonhuman primates and recent human studies established intracortical microstimulation (ICMS) in primary somatosensory cortex (S1) as a method of inducing discriminable artificial sensation. However, these artificial sensations do not
Michelle Armenta Salas +10 more
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Intracortical microstimulation parameters modulate flight behavior in pigeon [PDF]
Journal of Integrative Neuroscience, 2019 Pigeons have a natural affinity for travel by flight. Researchers have recently achieved modulation of pigeon locomotor behaviour by intracortical microstimulation.
Kun Zhao, Hong Wan, Zhigang Shang, Xinyu Liu, Lu Liu
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The Long-Term Stability of Intracortical Microstimulation and the Foreign Body Response Are Layer Dependent [PDF]
Frontiers in Neuroscience, 2022 Intracortical microstimulation (ICMS) of the somatosensory cortex (S1) can restore sensory function in patients with paralysis. Studies assessing the stability of ICMS have reported heterogeneous responses across electrodes and over time, potentially ...
Morgan E. Urdaneta +10 more
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Brain StimulationBackground: Intracortical microstimulation (ICMS) of the somatosensory cortex activates neurons around the stimulating electrodes and can elicit tactile sensations. Objective: It is not clear how the direct activation of cortical neurons influences their
Luke E. Osborn +15 more
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FMRI activity in the macaque cerebellum evoked by intracortical microstimulation of the primary somatosensory cortex: evidence for polysynaptic propagation. [PDF]
PLoS ONE, 2012 Simultaneous electrical microstimulation (EM) and functional magnetic resonance imaging (fMRI) is a useful tool for probing connectivity across brain areas in vivo.
Teppei Matsui +8 more
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Advanced ScienceTactile feedback is essential for grip force control when operating a neuroprosthesis. Due to limited knowledge of cortical sensorimotor coordination, artificial feedback is mostly counterintuitive, requiring training to be associated with grasping ...
Qi Zhang +9 more
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Responses of Cortical Neurons to Intracortical Microstimulation in Awake Primates. [PDF]
eNeuro, 2023 Abstract Intracortical microstimulation (ICMS) is commonly used in many experimental and clinical paradigms; however, its effects on the activation of neurons are still not completely understood. To document the responses of cortical neurons in awake nonhuman primates to stimulation, we recorded single-unit activity while delivering ...
Yun R +4 more
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Potential role of noise to improve intracortical microstimulation in tactile neuroprostheses
Neural Regeneration Research, 2021 Pedro Mabil +3 more
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Optimal interphase delay in biphasic current pulses facilitates neural circuit activation induced by microstimulation in the mouse visual cortex [PDF]
Frontiers in NeuroscienceCathodic-first biphasic current pulses are commonly employed in intracortical microstimulation. Due to the intricate arrangement of axons, somata, and dendrites in the cerebral cortex, membrane polarizations induced by the cathodic and subsequent anodic ...
Santa Fukuda, Yuki Hayashida
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