Results 21 to 30 of about 3,879 (175)

Intracortical Microstimulation Modulates Cortical Induced Responses. [PDF]

J Neurosci, 2018
Recent advances in cortical prosthetics relied on intracortical microstimulation (ICMS) to activate the cortical neural network and convey information to the brain. Here we show that activity elicited by low-current ICMS modulates induced cortical responses to a sensory stimulus in the primary auditory cortex (A1).
Voigt MB, Yusuf PA, Kral A.
europepmc   +4 more sources

Leveraging computational models to understand mechanisms of intracortical microstimulation

Brain Stimulation, 2023
Warren Grill, Karthik Kumaravelu, Aman Aberra, Angel Peterchev   +3 more
doaj   +2 more sources

Configuring intracortical microelectrode arrays and stimulus parameters to minimize neuron loss during prolonged intracortical electrical stimulation

Brain Stimulation, 2021
Background: Previous studies have shown that neurons of the cerebral cortex can be injured by implantation of, and stimulation with, implanted microelectrodes.
Douglas McCreery, Martin Han, Victor Pikov, Carol Miller   +3 more
doaj   +1 more source

Multimodal, longitudinal assessment of intracortical microstimulation. [PDF]

Prog Brain Res, 2011
The fundamental obstacle to neuroprostheses based on penetrating microstimulation is the tissue's response to the device insertion and to the application of the electrical stimulation. Our long-term goal is to develop multichannel microstimulation of central nervous tissue for clinical therapy.
Koivuniemi A, Wilks SJ, Woolley AJ, Otto KJ.   +3 more
europepmc   +4 more sources

Equalization for intracortical microstimulation artifact reduction [PDF]

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2013
We present a method for decreasing the duration of artifacts present during intra-cortical microstimulation (ICMS) recordings by using techniques developed for digital communications. We replace the traditional monophasic or biphasic current stimulation pulse with a patterned pulse stream produced by a Zero Forcing Equalizer (ZFE) filter after ...
Chu, Philip, Muller, Rikky, Koralek, Aaron, Carmena, Jose M, Rabaey, Jan M, Gambini, Simone   +5 more
openaire   +4 more sources

High density nanowire electrodes for intracortical microstimulation [PDF]

2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019
High-density electrodes with the nano feature size greatly enhance resolution and specificity during intracortical microstimulation. In this viewpoint, we fabricated and developed high-density nanowire (NW) electrodes, ~ 2.45×109 / cm2 that could directly stimulate specific region of the cortex with low current amplitude in the range of 120-180 μA. The
Srinivasu Valagerahally, Puttaswamy, Qiongfeng, Shi, David, Steele, Sam Jeffery, Fishlock, Chengkuo, Lee, James, McLaughlin   +5 more
openaire   +2 more sources

Phase-Specific Microstimulation Differentially Modulates Beta Oscillations and Affects Behavior

Cell Reports, 2020
Summary: It is widely accepted that Beta-band oscillations play a role in sensorimotor behavior. To further explore this role, we developed a hybrid platform to combine neural operant conditioning and phase-specific intracortical microstimulation (ICMS).
Oren Peles, Uri Werner-Reiss, Hagai Bergman, Zvi Israel, Eilon Vaadia   +4 more
doaj   +1 more source

The impact of closed-loop intracortical stimulation on neural activity in brain-injured, anesthetized animals

Bioelectronic Medicine, 2022
Background Acquired brain injuries, such as stroke, are a major cause of long-term disability worldwide. Intracortical microstimulation (ICMS) can be used successfully to assist in guiding appropriate connections to restore lost sensorimotor integration.
Marta Carè, Alberto Averna, Federico Barban, Marianna Semprini, Lorenzo De Michieli, Randolph J. Nudo, David J. Guggenmos, Michela Chiappalone   +7 more
doaj   +1 more source

Intracortical Microstimulation Elicits Human Fingertip Sensations [PDF]

, 2020
The restoration of cutaneous sensation to fingers and fingertips is critical to achieving dexterous prosthesis control for individuals with sensorimotor dysfunction. However, localized and reproducible fingertip sensations in humans have not been reported via intracortical microstimulation (ICMS) in humans.
Fifer, Matthew S, McMullen, David P, Thomas, Tessy M, Osborn, Luke E, Nickl, Robert W, Candrea, Daniel N, Pohlmeyer, Eric A, Thompson, Margaret C, Anaya, Manuel, Schellekens, Wouter, Ramsey, Nick F, Bensmaia, Sliman J, Anderson, William S, Wester, Brock A, Crone, Nathan E, Celnik, Pablo A, Cantarero, Gabriela L, Tenore, Francesco V   +17 more
openaire   +1 more source

Forelimb movements evoked by optogenetic stimulation of the macaque motor cortex

Nature Communications, 2020
Non-human primates are useful models for understanding the human brain but application of optogenetics to non-human primates is challenging. The authors used optogenetic intracortical microstimulation in the primary motor cortex of macaques to elicit ...
Hidenori Watanabe, Hiromi Sano, Satomi Chiken, Kenta Kobayashi, Yuko Fukata, Masaki Fukata, Hajime Mushiake, Atsushi Nambu   +7 more
doaj   +1 more source