Results 21 to 30 of about 3,871 (195)

A brain-machine interface instructed by direct intracortical microstimulation [PDF]

Frontiers in Integrative Neuroscience, 2009
Brain-machine interfaces (BMIs) establish direct communications between the brain and artificial actuators. As such, they hold considerable promise for restoring mobility and communication in patients suffering from severe body paralysis. To achieve this
Joseph E O'Doherty, Joseph E O'Doherty, Mikhail Lebedev, Mikhail Lebedev, Timothy L Hanson, Timothy L Hanson, Nathan Fitzsimmons, Nathan Fitzsimmons, Miguel A.L Nicolelis, Miguel A.L Nicolelis, Miguel A.L Nicolelis, Miguel A.L Nicolelis, Miguel A.L Nicolelis, Miguel A.L Nicolelis, Miguel A.L Nicolelis   +14 more
doaj   +3 more sources

Neural Modulation of the Primary Auditory Cortex by Intracortical Microstimulation with a Bio-Inspired Electronic System [PDF]

Bioengineering, 2020
Nowadays, the majority of the progress in the development of implantable neuroprostheses has been achieved by improving the knowledge of brain functions so as to restore sensorial impairments.
Maria Giovanna Bianco, Salvatore Andrea Pullano, Rita Citraro, Emilio Russo, Giovambattista De Sarro, Etienne de Villers Sidani, Antonino S. Fiorillo   +6 more
doaj   +2 more sources

Intracortical Microstimulation Modulates Cortical Induced Responses. [PDF]

J Neurosci, 2018
Recent advances in cortical prosthetics relied on intracortical microstimulation (ICMS) to activate the cortical neural network and convey information to the brain. Here we show that activity elicited by low-current ICMS modulates induced cortical responses to a sensory stimulus in the primary auditory cortex (A1).
Voigt MB, Yusuf PA, Kral A.
europepmc   +4 more sources

Layer-specific parameters of intracortical microstimulation of the somatosensory cortex. [PDF]

J Neural Eng, 2021
Abstract Objective. Intracortical microstimulation of the primary somatosensory cortex (S1) has shown great progress in restoring touch sensations to patients with paralysis. Stimulation parameters such as amplitude, phase duration, and frequency can influence the quality of the evoked percept as well as the amount of ...
Urdaneta ME, Kunigk NG, Delgado F, Fried SI, Otto KJ.   +4 more
europepmc   +3 more sources

Local Neuronal Responses to Intracortical Microstimulation in Rats' Barrel Cortex Are Dependent on Behavioral Context [PDF]

Frontiers in Behavioral Neuroscience, 2022
The goal of cortical neuroprosthetics is to imprint sensory information as precisely as possible directly into cortical networks. Sensory processing, however, is dependent on the behavioral context.
Sergejus Butovas, Cornelius Schwarz
doaj   +2 more sources

Conveying tactile object characteristics through customized intracortical microstimulation of the human somatosensory cortex [PDF]

Nature Communications
Microstimulation of the somatosensory cortex can evoke tactile percepts in people with spinal cord injury, providing a means to restore touch. While location and intensity can be reliably conveyed, two issues that prevent creating more complex ...
Ceci Verbaarschot, Vahagn Karapetyan, Charles M. Greenspon, Michael L. Boninger, Sliman J. Bensmaia, Bettina Sorger, Robert A. Gaunt   +6 more
doaj   +3 more sources

The Long-Term Stability of Intracortical Microstimulation and the Foreign Body Response Are Layer Dependent [PDF]

Frontiers in Neuroscience, 2022
Intracortical microstimulation (ICMS) of the somatosensory cortex (S1) can restore sensory function in patients with paralysis. Studies assessing the stability of ICMS have reported heterogeneous responses across electrodes and over time, potentially ...
Morgan E. Urdaneta, Nicolas G. Kunigk, Seth Currlin, Francisco Delgado, Shelley I. Fried, Shelley I. Fried, Kevin J. Otto, Kevin J. Otto, Kevin J. Otto, Kevin J. Otto, Kevin J. Otto   +10 more
doaj   +2 more sources

Neural mechanisms of the temporal response of cortical neurons to intracortical microstimulation [PDF]

Brain Stimulation
Background: Intracortical microstimulation (ICMS) is used to map neuronal circuitry in the brain and restore lost sensory function, including vision, hearing, and somatosensation.
Karthik Kumaravelu, Warren M. Grill
doaj   +2 more sources

Multimodal, longitudinal assessment of intracortical microstimulation. [PDF]

Prog Brain Res, 2011
The fundamental obstacle to neuroprostheses based on penetrating microstimulation is the tissue's response to the device insertion and to the application of the electrical stimulation. Our long-term goal is to develop multichannel microstimulation of central nervous tissue for clinical therapy.
Koivuniemi A, Wilks SJ, Woolley AJ, Otto KJ.   +3 more
europepmc   +4 more sources

Virtual active touch using randomly patterned intracortical microstimulation. [PDF]

IEEE Trans Neural Syst Rehabil Eng, 2012
Intracortical microstimulation (ICMS) has promise as a means for delivering somatosensory feedback in neuroprosthetic systems. Various tactile sensations could be encoded by temporal, spatial, or spatiotemporal patterns of ICMS. However, the applicability of temporal patterns of ICMS to artificial tactile sensation during active exploration is unknown,
O'Doherty JE, Lebedev MA, Li Z, Nicolelis MA.   +3 more
europepmc   +4 more sources