Results 91 to 100 of about 27,314 (241)

Plasma POSTN Derived From Bile Proteome Is a Promising Biomarker for Cholangiocarcinoma With Efficacy Comparable and Complementary to CA19.9

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n 
Lichieh Julie Chu   +6 more
wiley   +1 more source

Deep Learning for the Digital Pathologic Diagnosis of Cholangiocarcinoma and Hepatocellular Carcinoma: Evaluating the Impact of a Web-based Diagnostic Assistant [PDF]

open access: yesarXiv, 2019
While artificial intelligence (AI) algorithms continue to rival human performance on a variety of clinical tasks, the question of how best to incorporate these algorithms into clinical workflows remains relatively unexplored. We investigated how AI can affect pathologist performance on the task of differentiating between two subtypes of primary liver ...
arxiv  

Nectin4‐targeted molecular imaging in solid tumors: Current status and future perspectives

open access: yesVIEW, EarlyView.
In this review, we provide a concise overview of the mechanisms by which Nectin4 contributes to the pathogenesis of various malignancies and detail the classes of Nectin4‐targeted molecular probes. We then delve into the significant advancements in Nectin4‐targeted molecular imaging techniques, encompassing both nuclear medicine and optical imaging ...
Yongshun Liu   +6 more
wiley   +1 more source

Current principles for the surgical treatment of intrahepatic cholangiocarcinoma

open access: yesJournal of Mind and Medical Sciences
Intrahepatic cholangiocarcinoma is one of the most aggressive forms of cancer. It is usually diagnosed in advanced stages of the disease, mainly because it is asymptomatic for a long time after the onset.
Catalin Savin   +12 more
doaj   +1 more source

Pituitary adenoma management and outcomes according to hospital case volume and facility type

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
Abstract Objectives This study evaluates the influence of facility volume and type on the treatment and outcomes of pituitary adenoma (PA). Methods The 2004–2016 National Cancer Database was queried for patients with PA receiving definitive treatment. Tumor size represented the largest diameter of the primary tumor.
Khodayar Goshtasbi   +8 more
wiley   +1 more source

Minute nodular intrahepatic cholangiocarcinoma. [PDF]

open access: bronze, 1998
Masakazu Yamamoto   +3 more
openalex   +2 more sources

Does resection improve overall survival for intrahepatic cholangiocarcinoma with nodal metastases?

open access: yesSurgery Open Science, 2020
Background: The potential benefit of surgical resection of intrahepatic cholangiocarcinoma in patients with locoregionally advanced disease has not been definitively determined.
Patrick J. Sweigert, MD   +7 more
doaj  

Endoscopic management of primary sclerosing cholangitis

open access: yesDigestive Endoscopy, EarlyView.
Primary sclerosing cholangitis (PSC) is a progressive autoimmune hepatobiliary disease characterized by fibrotic strictures in the bile ducts, leading to chronic cholestasis and cirrhosis. Magnetic resonance cholangiopancreatography (MRCP) is a noninvasive method for evaluating the condition of the bile ducts, and has high sensitivity and specificity ...
Suguru Mizuno   +8 more
wiley   +1 more source

Whole-exome sequencing reveals the origin and evolution of hepato-cholangiocarcinoma

open access: yesNature Communications, 2018
Hepatocellular-cholangiocarcinoma (H-ChC) is a rare subtype of liver cancer with features of hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Here, the authors utilize whole exome sequencing to highlight the monoclonal origin and stemness of
Anqiang Wang   +11 more
doaj   +1 more source

Endoscopic diagnosis of immunoglobulin G4‐related sclerosing cholangitis

open access: yesDigestive Endoscopy, EarlyView.
Immunoglobulin G4 (IgG4)‐related sclerosing cholangitis (IgG4‐SC) is a distinct form of sclerosing cholangitis frequently associated with autoimmune pancreatitis and is recognized as a biliary manifestation of IgG4‐related disease. Endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasonography (EUS) are key diagnostic modalities ...
Itaru Naitoh   +2 more
wiley   +1 more source

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