AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Successful orthotopic liver transplantation in an adult patient with sickle cell disease and review of the literature [PDF]
, 2013 Sickle cell disease can lead to hepatic complications ranging from acute hepatic crises to chronic liver disease including intrahepatic cholestasis, and iron overload.
Blinder, Morey A. +7 more
core +2 more sources
Prevalence and Pregnancy Outcomes of Intrahepatic Cholestasis of Pregnancy
Journal of Nepal Health Research Council, 2021 Background: Intrahepatic cholestasis of pregnancy is a common pregnancy-specific liver disease associated with increased risk of adverse fetal and maternal outcomes. We sought to determine its prevalence, risk factors and feto-maternal outcomes. Methods:
Deekshanta Sitaula +4 more
doaj +1 more source
Pakistan Armed Forces Medical Journal, 2021 Objectives: To evaluate the principal risk factors associated with development of intrahepatic cholestasis of pregnancy (ICP) in patients presenting to a tertiary care hospital. Study Design: Case control study.
Rabiah Anwar +5 more
doaj
The Lancet, 2019 Summary Background Intrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes, but the association with the concentration of specific biochemical markers is unclear.
Caroline Ovadia +39 more
semanticscholar +1 more source
The non-HDL-C to APOB ratio as a predictor of inaccurate LDL-C measurement in patients with chronic intrahepatic cholestasis and jaundice: a retrospective study [PDF]
PeerJBackground Cholestasis is characterized by the accumulation of bile in the liver or biliary system due to obstruction or impaired flow, necessitating lipid profiling to assess lipid metabolism abnormalities.
Yongjiang Cheng +3 more
doaj +2 more sources
Alpha-1 Antitrypsin Z Variant (AAT PI*Z) as a Risk Factor for Intrahepatic Cholestasis of Pregnancy
Frontiers in Genetics, 2021 Background: Intrahepatic cholestasis of pregnancy (ICP; prevalence 0.2–15.6%) is the most common pregnancy-related liver disorder. It may have serious consequences for a pregnancy, including increased risk of preterm delivery, meconium staining of ...
Przemyslaw Kosinski +12 more
doaj +1 more source
Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology [PDF]
, 2013 Cholangiocytes are epithelial cells lining the biliary epithelium. Cholangiocytes play several key roles in the modification of ductal bile and are also the target cells in chronic cholestatic liver diseases (i.e., cholangiopathies) such as PSC, PBC ...
Alvaro, Domenico +6 more
core +1 more source
Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]
, 2020 In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco +4 more
core +1 more source
Progressive familial intrahepatic cholestasis
Definitions, 2020 Neonatal cholestasis is one of the commonest presentations in the field of pediatric hepatol‐ ogy and gastroenterology and constitutes the major indication for liver transplantation be‐ low two years of age. Unfortunately, in spite of being common, fewer
R. Khanna, Vipul Gautam
semanticscholar +1 more source