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Management of intrahepatic cholestasis of pregnancy
Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disease during pregnancy, characterized by otherwise unexplained pruritus in late second and third trimester of pregnancy and elevated bile acids and/or transaminases. ICP is associated with an increased risk of adverse perinatal outcomes for the fetus and the later development of ...
Marschall, Hanns-Ulrich,
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Intrahepatic cholestasis of pregnancy
Česká gynekologieObjective: The aim of this work is to summarize current scientific information focusing on the diagnosis, management, and treatment of intrahepatic cholestasis in pregnancy according to available literature. Methodology: Literature sources were searched using the Web of Science, Scopus, and PubMed/Medline databases.
Luděk, Kostka +2 more
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Intrahepatic cholestasis of pregnancy
Abstract Intrahepatic cholestasis of pregnancy is a pregnancy-specific liver disease characterised by maternal pruritus and raised serum bile acids. It is of multifactorial aetiology with genetic influences. The disease has potential implications for the fetus, linked to the serum bile acid concentration in the blood, including preterm labour ...
Chivers, Sian, Williamson, Catherine
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Intrahepatic Cholestasis of Pregnancy
Nursing for Women's Health, 2015Itching is commonly reported by pregnant women and may be due to physiologic changes of pregnancy or could indicate a more serious health concern. Intrahepatic cholestasis of pregnancy, while classified as a pregnancy dermatosis, is actually a liver disease of pregnancy associated with significant fetal mortality and morbidity, as well as lifelong ...
Cathi, Phillips, Margaret, Boyd
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Intrahepatic cholestasis of pregnancy
Clinics in Liver Disease, 2004Patients with ICP should be considered to have a high-risk pregnancy. Once the diagnosis of ICP is suspected, usually because of generalized pruritus, it should be confirmed by liver function tests, and other causes of cholestasis should be ruled out.
Caroline A, Riely, Yannik, Bacq
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Intrahepatic cholestasis of pregnancy
Current Treatment Options in Gastroenterology, 2003Intrahepatic cholestasis of pregnancy (or obstetric cholestasis) is a liver disorder that occurs in late pregnancy. Despite the potential adverse maternal and fetal/neonatal outcomes, cholestasis of pregnancy is often neglected and treated expectantly.
Frank, Lammert +2 more
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Pregnancy Outcome With Intrahepatic Cholestasis
Obstetrics & Gynecology, 1999To determine the risk of adverse pregnancy outcomes resulting from intrahepatic cholestasis.We analyzed 91 women with singleton pregnancies complicated by cholestasis who gave birth at Kuopio University Hospital from January 1990 to December 1996.
S, Heinonen, P, Kirkinen
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Estrogens in Intrahepatic Cholestasis of Pregnancy
Obstetrics & Gynecology, 2000To determine whether estrogen production and excretion are impaired in gravidas with intrahepatic cholestasis.Plasma and urine samples were collected from 13 women from the United States and Chile at 35-38 weeks' gestation with mild (n = 9) or severe (n = 4) intrahepatic cholestasis of pregnancy.
K K, Leslie +5 more
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Intrahepatic cholestasis of pregnancy
Seminars in Perinatology, 1998Intrahepatic cholestasis of pregnancy (ICP) is a disease of the third trimester of pregnancy involving pruritus and elevated bile acid levels. Its pathogenesis likely involves a genetic hypersensitivity to estrogen. Once thought to be benign for both mother and fetus, ICP has been associated with increased rates of fetal morbidity and mortality and an ...
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Intrahepatic cholestasis of pregnancy in twin pregnancies
Journal of Hepatology, 1989To clarify whether the increase in estrogen levels occurring during twin pregnancies (TP) is associated with a greater risk of developing intrahepatic cholestasis of pregnancy (ICP), we followed up 62 consecutive patients with TP and compared them with single pregnancies delivered in our hospital during 1 year.
M C, Gonzalez +8 more
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