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Intrahepatic cholestasis of pregnancy
Evidence Based Womenʼs Health Journal, 2013Intrahepatic cholestasis of pregnancy is a pregnancy-specific liver disorder. It is characterized by pruritus, jaundice, and elevated serum bile acids, mainly in the third trimester, with different fetal outcomes.
Mohammed K. Ali +4 more
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Estrogens in Intrahepatic Cholestasis of Pregnancy
Obstetrics & Gynecology, 2000To determine whether estrogen production and excretion are impaired in gravidas with intrahepatic cholestasis.Plasma and urine samples were collected from 13 women from the United States and Chile at 35-38 weeks' gestation with mild (n = 9) or severe (n = 4) intrahepatic cholestasis of pregnancy.
K K, Leslie +5 more
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Intrahepatic cholestasis of pregnancy in twin pregnancies
Journal of Hepatology, 1989To clarify whether the increase in estrogen levels occurring during twin pregnancies (TP) is associated with a greater risk of developing intrahepatic cholestasis of pregnancy (ICP), we followed up 62 consecutive patients with TP and compared them with single pregnancies delivered in our hospital during 1 year.
M C, Gonzalez +8 more
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Intrahepatic cholestasis of pregnancy
Seminars in Perinatology, 1998Intrahepatic cholestasis of pregnancy (ICP) is a disease of the third trimester of pregnancy involving pruritus and elevated bile acid levels. Its pathogenesis likely involves a genetic hypersensitivity to estrogen. Once thought to be benign for both mother and fetus, ICP has been associated with increased rates of fetal morbidity and mortality and an ...
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[Intrahepatic cholestasis of pregnancy].
Journal de gynecologie, obstetrique et biologie de la reproduction, 2008Intrahepatic cholestasis of pregnancy is the most common liver disorder unique to pregnancy in women without hypertension. The cause of intrahepatic cholestasis of pregnancy is still under discussion but genetic and hormonal factors are predominant. The main symptom is skin pruritus, associated with increase in serum transaminase activities and bile ...
L, Sentilhes, Y, Bacq
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Management of intrahepatic cholestasis of pregnancy
Expert Review of Gastroenterology & Hepatology, 2015Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disease during pregnancy, characterized by otherwise unexplained pruritus in late second and third trimester of pregnancy and elevated bile acids and/or transaminases. ICP is associated with an increased risk of adverse perinatal outcomes for the fetus and the later development of ...
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Intrahepatic Cholestasis of Pregnancy
Obstetrics & Gynecology, 2014Cassandra E, Henderson +3 more
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Intrahepatic Cholestasis of Pregnancy
2010Intrahepatic cholestasis of pregnancy (ICP) is an intra-hepatic cholestasis of unknown origin occurring in the second or third trimester of pregnancy. It is characterized by general pruritus and an increase in total bile acid levels in serum. The outcome for the mother is excellent, though the sequelae for the fetus may be grave [5, 14].
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