Results 41 to 50 of about 2,032 (137)

Pioneering Women Shaping the Field of Biocatalysis

ChemCatChem, Volume 17, Issue 10, May 22, 2025.
Groundbreaking works of women scientists in biocatalysis are highlighted in this article. Their innovative contributions are categorized in four interrelated research areas, collectively driving advancements in enzymatic biotransformations. Abstract In this perspective article, we celebrate the accomplishments of female‐led research groups in ...
Ana I. Benítez‐Mateos, Caroline E. Paul, Sandy Schmidt, Martina Letizia Contente   +3 more
wiley   +1 more source

Characterization of C-S Lyase from C. diphtheriae [PDF]

, 2013
The emergence of antibiotic resistance in microbial pathogens requires the identification of new antibacterial drugs. The biosynthesis of methionine is an attractive target because of its central importance in cellular metabolism.
Allegrini, Alessandra, Astegno, Alessandra, Cellini, Barbara, Dominici, Paola, Giorgetti, Alejandro   +4 more
core   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Application of Enzymes in Regioselective and Stereoselective Organic Reactions [PDF]

, 2020
Nowadays, biocatalysts have received much more attention in chemistry regarding their potential to enable high efficiency, high yield, and eco-friendly processes for a myriad of applications.
Duke, Colbee N., Epley, Sarah E., Lii, Payton H., Mu, Ruipu, Roberts, Patty J., Todd, London C., Wamsley, Max C., Wang, Zhaoshuai   +7 more
core   +2 more sources

Expression of endochitinase and exochitinase in lettuce chloroplasts increases plant biomass and kills fungal pathogen Candida albicans

Plant Biotechnology Journal, Volume 23, Issue 5, Page 1437-1451, May 2025.
Expression of exochitinase and endochitinase in lettuce highlights the potential of chloroplast genetic engineering for sustainable agriculture and biomedical applications, offering a safer alternative to chemical fertilizers and fungicides. Summary Lettuce (Lactuca sativa) is a popular leafy vegetable with global production of ~28 million Mt ...
Iqra Fatima, Geetanjali Wakade, Niaz Ahmad, Henry Daniell   +3 more
wiley   +1 more source

Expanding the Substrate Scope of C−N Lyases by Homologue Discovery

ChemBioChem, Volume 26, Issue 7, April 1, 2025.
A homology‐based strategy is employed to identify and biochemically characterize 13 enzymes homologous to ethylenediamine‐N,N‐disuccinic acid (EDDS) lyase. Several homologues exhibit a broadened substrate scope, accepting L‐amino acids for the enantioselective hydroamination of fumarate to produce the corresponding aminopolycarboxylic acids.
Laura Bothof, Riccardo Iacovelli, Pieter G. Tepper, Gerrit J. Poelarends   +3 more
wiley   +1 more source

Comparative Metabolomic Analysis of Phenolic Compounds in Different Ramulus Mori (Sangzhi) Based on UPLC‐ESI‐MS/MS

eFood, Volume 6, Issue 2, April 2025.
A study on Ramulus mori (Sangzhi) from various regions in China revealed significant differences in polyphenol and flavonoid contents, with the Xinjiang variety (XJYS) showing the highest levels. Using UPLC‐ESI‐MS/MS technology, 128 phenolic metabolites were identified, with 17 differential ones screened out.
Yi Wang, Sheng Zhou, Chenlei Li, Yuyi Shen, Zhenjiang Wang, Xiaojie Yan, Wenkui Dai   +6 more
wiley   +1 more source

Enzymatic Valorization of Fatty Acids in Oleochemical Synthesis

European Journal of Lipid Science and Technology, Volume 127, Issue 3, March 2025.
Fatty acids are versatile feedstock for biocatalytic transformation into building blocks. ABSTRACT Fatty acids derived from renewable resources, such as vegetable oils, serve as essential feedstocks in various industries, including surfactants, cosmetics, lubricants, and polymers.
Florian Tieves, Frank Hollmann
wiley   +1 more source

Paradigms of convergent evolution in enzymes

The FEBS Journal, Volume 292, Issue 3, Page 537-555, February 2025.
Some enzymes are able to catalyse the same reaction despite possessing different structures. Here, we used a combined strategy of analysing published literature and knowledge‐based computational resources to explore this. We conclude that multiple varieties of convergent functional evolution exist to date, but that it is necessary to investigate ...
Ioannis G. Riziotis, Jenny C. Kafas, Gabriel Ong, Neera Borkakoti, António J. M. Ribeiro, Janet M. Thornton   +5 more
wiley   +1 more source

An Enzymatic Prodrug‐like Route to Thio and Selenoamides [PDF]

6‐Thioguanine (6TG) is a clinically used antitumor agent that was rationally designed as a DNA‐targeting antimetabolite, but it also occurs naturally. 6TG is a critical virulence factor produced by Erwinia amylovorans , a notorious plant pathogen that ...
Dunbar, Kyle L., Hertweck, Christian, Ishida, Keishi, Litomska, Agnieszka   +3 more
core   +1 more source