Results 51 to 60 of about 140,818 (295)

Cellular immune response of Staphylococcus aureus enterotoxin B in Balb/c mice through intranasal infection [PDF]

Veterinary World, 2022
Background and Aim: Staphylococcus aureus produces various superantigen exotoxins, including staphylococcal enterotoxin B (SEB). It causes fatal anaphylactic reactions and toxic shock.
Hidayatun Nisa Purwanasari, Amanda Tri Utami Permatasari, Fajar Budi Lestari, Madarina Wasissa, Khusnan Zaini, Siti Isrina Oktavia Salasia   +5 more
doaj   +1 more source

Oxytocin treatment in pediatric populations

Frontiers in Behavioral Neuroscience, 2014
The role of endogenous oxytocin as neuromodulator of birth, lactation and social behaviors is well-recognized. Moreover, the use of oxytocin as a facilitator of social and other behaviors is becoming more and more accepted.
Adrienne Elise Taylor, Hsu-en eLee, Hsu-en eLee, Femke T.A. Buisman-Pijlman   +3 more
doaj   +1 more source

A Comparative Study on Intranasal Versus Intravenous Lorazepam in the Management of Acute Seizure in Children [PDF]

Folia Medica, 2021
Introduction: The acute seizure in childhood is a medical emergency which is usually managed by benzodiazepines used as a first line of therapy. There are no strict guidelines of using intranasal lorazepam in India.
Nandan Rudra, Taraknath Ghosh, Uttam Kumar Roy   +2 more
doaj   +3 more sources

Attenuated Influenza Virions Expressing the SARS-CoV-2 Receptor-Binding Domain Induce Neutralizing Antibodies in Mice

Viruses, 2020
An effective vaccine is essential for controlling the spread of the SARS-CoV-2 virus. Here, we describe an influenza virus-based vaccine for SARS-CoV-2.
Andrea N. Loes, Lauren E. Gentles, Allison J. Greaney, Katharine H. D. Crawford, Jesse D. Bloom   +4 more
doaj   +1 more source

Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets

bioRxiv, 2020
Containment of the COVID-19 pandemic requires reducing viral transmission. SARS-CoV-2 infection is initiated by membrane fusion between the viral and host cell membranes, mediated by the viral spike protein.
R. D. de Vries, K. Schmitz, F. Bovier, D. Noack, B. Haagmans, S. Biswas, B. Rockx, S. Gellman, C. Alabi, R. D. de Swart, A. Moscona, M. Porotto   +11 more
semanticscholar   +1 more source

Targeting Intracranial Tumours with a Combination of RNA and Chemotherapy

Pharmaceutics
Glioblastoma multiforme (GBM) is a fast-growing and aggressive brain tumour, which remains largely resistant to treatment; the prognosis for patients is poor, with a median survival time of about 12–18 months, post diagnosis.
Abdulhamid S. Fatani, Andreas G. Schätzlein, Ijeoma F. Uchegbu   +2 more
doaj   +1 more source

Safety and immunogenicity of an intranasal sendai virus-based vaccine for human parainfluenza virus type I and respiratory syncytial virus (SeVRSV) in adults

Human Vaccines & Immunotherapeutics, 2021
SeVRSV is a replication-competent Sendai virus (SeV)-based vaccine carrying the respiratory syncytial virus (RSV) fusion protein (F) gene. Unmanipulated, non-recombinant SeV is a murine parainfluenza virus type 1 (PIV-1) and serves as a Jennerian vaccine
Felicia Scaggs Huang, David I. Bernstein, Karen S. Slobod, Allen Portner, Toru Takimoto, Charles J. Russell, Michael Meagher, Bart G. Jones, Robert E. Sealy, Christopher Coleclough, Kristen Branum, Michelle Dickey, Kristen Buschle, Monica McNeal, Mat Makowski, Aya Nakamura, Julia L. Hurwitz   +16 more
doaj   +1 more source

Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury.

ACS Nano, 2019
Individuals with spinal cord injury (SCI) usually suffer from permanent neurological deficits, while spontaneous recovery and therapeutic efficacy are limited.
Shaowei Guo, Nisim Perets, O. Betzer, Shahar Ben-Shaul, A. Sheinin, I. Michaelevski, R. Popovtzer, D. Offen, S. Levenberg   +8 more
semanticscholar   +1 more source

Atomized Intranasal Sedation Efficacy in Children Undergoing Dental Treatment: A Comparative Randomized Clinical Study

Advances in Human Biology
Introduction: Dental fear and anxiety, especially in children, are the most common reason for avoiding dental treatment. Paediatric dental sedation as a means of pharmacologic behaviour management is gaining momentum to manage young difficult children ...
Megha Patel, Kalpesh Vaishnav, Chintan Patel, Miral Mehta, Santosh Kumar   +4 more
doaj   +1 more source

Effect of Intranasal Remifentanil versus Lidocaine on Facilitation of Laryngeal Mask Airway Insertion and Cardiovascular Response: A Double-blind Clinical Trial Study [PDF]

Bulletin of Emergency and Trauma
Objective: This study aimed to assess and compare the effects of intranasal administration of lidocaine andremifentanil on the condition of LMA insertion and cardiovascular response.Methods: From March 2019 to March 2020, this double-blind randomized ...
Hamidreza Shetabi, hossein Mahjoubipour, mona bahmani   +2 more
doaj   +1 more source