Results 111 to 120 of about 57,366 (267)

In Vivo Effects of N,N‐Diethyl‐Meta‐Toluamide (DEET) Exposure on Sinonasal Epithelia in a Murine Model

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Environmental factors, including airborne toxicants, are thought to contribute to the pathogenesis of chronic rhinosinusitis, although the exact mechanism is not fully understood. The purpose of this pilot study is to assess the impact of pesticide, N,N‐diethyl‐meta‐toluamide (DEET), on the sinonasal epithelium using an in vivo murine model ...
Jivianne T. Lee, Melodyanne Y. Cheng, Eri S. Srivatsan, Neda A. Moatamed, Saroj K. Basak   +4 more
wiley   +1 more source

Role of intranasal fentanyl in breakthrough pain management in cancer patients

Cancer Management and Research, 2010
Wojciech LeppertDepartment of Palliative Medicine, Poznan University of Medical Sciences, Poznan, PolandAbstract: Fentanyl is a strong opioid analgesic, which is commonly used in the form of a transdermal patch for the treatment of chronic cancer pain ...
Wojciech Leppert
doaj  

Radiofrequency Ablation Versus Laser Neurolysis of the Posterior Nasal Nerve in Patients With Chronic Rhinitis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare the clinical outcomes of radiofrequency ablation of the intraturbinate segment of the posterior nasal nerve (RAPN) alone versus combined RAPN with CO₂ laser posterior nasal nerve neurolysis (RPN3) in patients with chronic rhinitis refractory to medical therapy. Study Design Retrospective cohort study.
Chia‐Chen Lin, Yi‐Li Hwang, Jyun‐Yi Liao, Han‐Lo Teng, Ting‐Yu Shih, Chien‐Yu Huang   +5 more
wiley   +1 more source

Clinical and pharmacokinetics overview of intranasal administration of fentanyl. [PDF]

Heliyon, 2023
Nakhaee S, Saeedi F, Mehrpour O.
europepmc   +1 more source

Efficacy and Safety of Dexmedetomidine‐Esketamine Versus Dexmedetomidine Alone as Premedication for Pediatric Anesthesia Induction: A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Emergence delirium (ED) is a common complication in pediatric anesthesia. Although intranasal dexmedetomidine (DEX) is widely used, its application is constrained by a slow onset, residual risk of ED in some patients, and risks such as bradycardia and hypotension.
Munder Lateiresh, Alhasan Altayf, Ayham Qatza, Abubaker Alghazal, Hasan Al‐sakkaf, Muhammed Elhadi   +5 more
wiley   +1 more source

Glucocorticoid‐Induced TNFR‐Related Ligand as a Biomarker for Diagnosis and Severity of Asthma in Children

Pediatric Discovery, EarlyView.
Our study demonstrates elevated GITRL expression in HDM‐exposed dendritic cells (in vitro), murine asthma models, and pediatric asthma patients, and reveals a direct association between GITRL levels and disease severity in children. ABSTRACT Currently, there are no reliable pediatric biomarkers for assessing the severity of asthma. Therefore, the study
Yuehan Li, Yan Li, Jinying Xiang, Yinying Ren, Mi Zhou, Fang Deng, Zhou Fu, Fengxia Ding   +7 more
wiley   +1 more source

Design of Polycation-Functionalized Resveratrol Nanocrystals for Intranasal Administration. [PDF]

Pharmaceutics
Bonaccorso A, Zingale E, Caruso G, Privitera A, Carbone C, Lo Faro MJ, Caraci F, Musumeci T, Pignatello R.   +8 more
europepmc   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Progress, critical challenges, and translational prospects of intranasal administration of botanical essential oils for the treatment of depression. [PDF]

Front Pharmacol
Cheng K, Zhao H, He K, Xia X, Wang Y, Wang S, Li W.   +6 more
europepmc   +1 more source

G Protein–Coupled Receptors in Olfactory Signaling and Related Disorders: Mechanisms and Therapeutic Implications

Sensory Neuroscience, EarlyView.
This schematic highlights GPCRs as the central hub of olfactory signaling in health and disease. The central GPCR shows odorant activation and downstream pathways. Surrounding quadrants illustrate four GPCR‐mediated themes: odor perception and adaptation, mucosal immunity and regeneration, memory consolidation via neural circuits, and GPCR‐related ...
Zishuo Guo, Hongjie Du, Fanyu Yuan, Yuhan Dong, Fangyuan Zhu, Jian Liu, Chengzhilin Li, Xu Guo, Zhaoze Yang, Wenwen Qi, Ming Xia, Chengcheng Liu   +11 more
wiley   +1 more source