Results 181 to 190 of about 65,548 (298)

A novel bispecific nanobody protects mice against RSV infection via intranasal administration. [PDF]

J Virol
Zhang M, Qin L, Guo R, Li J, Huang S, Sheng C, Xiang Y.   +6 more
europepmc   +1 more source

Treatment Dose Increase Versus Co‐Medication in Allergic Rhinitis: Systematic Review With Dose–Response Network Meta‐Analysis

Allergy, EarlyView.
ABSTRACT Background To achieve adequate symptom control, patients with allergic rhinitis (AR) often need to increase their medication dose or add other treatments (co‐medication). We aimed to perform a systematic review to compare the efficacy and safety of AR medications for increased dose versus co‐medication.
Bernardo Sousa‐Pinto, Rafael José Vieira, Sara Gil‐Mata, Ana Margarida Pereira, Vítor Henrique Duarte, Antonio Bognanni, Manuel Marques‐Cruz, Paweł Jemioło, Mattia Giovannini, Danilo di Bona, Arnav Agarwal, Mark S. Dykewicz, Mohamed H. Shamji, Maria Jose Torres, Torsten Zuberbier, Ludger Klimek, Alexandro W. L. Chu, Holger J. Schünemann, Guido Schwarzer, João A. Fonseca, Jean Bousquet, on behalf of the ARIA 2024–2025 systematic reviews group, Ana Teixeira‐Ferreira, André Ferreira, António Cardoso‐Fernandes, Despo Ierodiakonou, Diana Portela, Ewa Borowiack, Ewelina Sadowska, Henrique Ferreira‐Cardoso, Hugo Viegas, Izabel Pera Calvi, João Castro‐Teles, José Laerte Boechat, Juliana Pereira‐Macedo, Maria Inês Torres, Marta Soares Pereira, Miguel Campos‐Lopes, Nuno Lourenço‐Silva, Pau Riera‐Serra, Paula Perestrelo, Raquel Albuquerque‐Costa, Renato Ferreira‐da‐Silva, Rita A. Silva Ribeiro, Tuuli Thomander   +44 more
wiley   +1 more source

A Single-Molecule Pleuripotent Scaffold for Combinational Therapy of Alzheimer's Disease via Intranasal Administration. [PDF]

Adv Sci (Weinh)
Gao JM, Li WB, Chen NN, Yi Y, Wang ZH, Chen X, Zhao YY, Yuan ZL, Gao J, Pan YC, Guo DS, Gong QH.   +11 more
europepmc   +1 more source

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

Allergy, EarlyView.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton, Manuel A. R. Ferreira, Wei Keat Lim, Carlo Sidore, Matthew F. Wipperman, Wenzhen Ge, Xue Song, Changming Xia, Julie E. Horowitz, Andrea T. Hooper, Sara C. Hamon, Jennifer Maloney, Jamie M. Orengo, Zhen Chen, Stephanie Amato Ricci, Bolanle Akinlade, Aris Baras, Gary Herman, Brandy L. Bennett, George D. Yancopoulos   +19 more
wiley   +1 more source

Intranasal administration of human mesenchymal stromal cell-derived small extracellular vesicles delays disease progression in the SOD1(G93A) mouse model. [PDF]

Mol Brain
Hirota R, Lankford KL, Nakazaki M, Toyoshima M, Kocsis JD.   +4 more
europepmc   +1 more source

Modification of a breast pump suction pattern increases milk yield during the first 4 days postpartum

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Adding 5 min of nutritive suction to a standard pumping protocol significantly increases early milk removal in the first 4 days postpartum. This simple adjustment is particularly effective in the first 2 days, when colostrum volumes are low. Optimizing early pumping strategies may improve access to colostrum and support lactation initiation in mothers ...
Theresia Margaretha Nicole Manshanden, Danielle Kaye Prime, Fedde Scheele, Joost Velzel   +3 more
wiley   +1 more source

Intranasal administration of broad-spectrum macrocyclic peptide inhibitor protects against SARS-CoV-2 Omicron variants. [PDF]

Nat Commun
Wang M, Yang J, Tan Y, Yuan S, Shi G, Peng Q, Li Y, Poon VK, Chan CC, Xiao N, Zhang AJ, Xie Y, Li J, Luo H, Fu Y, Chen Y, Compton AA, Zhang Y, Yang Y, Gao GF, Hou H, Chan JF, Yin Y, Shi Y.   +23 more
europepmc   +1 more source

Prenatal and childhood exposure to smoking and retinal nerve fibre layer thickness: A meta‐analysis of three independent birth cohorts

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine retinal nerve fibre layer (RNFL) characteristics in relation to prenatal and postnatal smoking exposure in three independent birth cohorts: two Danish and one Australian cohort. Methods A combined meta‐analysis of peripapillary retinal nerve fibre thickness in the Copenhagen Prospective Studies on Asthma in Childhood 2000 ...
Linna Zhu, Inger Christine Munch, Samantha Sze‐Yee Lee, David A. Mackey, Tamo Sultan, Klaus Bønnelykke, Bo Chawes, Michael Larsen, Nicklas Brustad   +8 more
wiley   +1 more source

Brain Delivery Strategies for Biomacromolecular Drugs: Intranasal Administration. [PDF]

Int J Nanomedicine
Wu H, Li C, Yuan H, Zhao J, Li S.
europepmc   +1 more source

Intranasal Administration of SARS-CoV-2 ORF8 Accessory Protein Increases Blood Pressure and Oxidative Stress in Different Tissues of Male BALB/c Mice. [PDF]

Viruses
Pavon-Martinez KA, Visoso-Carvajal G, Campi-Caballero R, García-Machorro J, Espinosa-Raya J.   +4 more
europepmc   +1 more source