Results 211 to 220 of about 96,176 (305)

Effect of intranasal administration of Erigeron annuus and Carthamus tinctorius extracts in a rat model of olfactory dysfunction induced by 3-methylindole. [PDF]

PLoS One
Jeong M, Kwon H, Kim Y, Hyun KY, Ju Y, Choi GE, Chang CL.   +6 more
europepmc   +1 more source

The Septoplasty Healthcare Monitor: An Outcome Assessment Infrastructure to Enhance the Quality and Transparency of Care

Clinical Otolaryngology, EarlyView.
ABSTRACT Objective and Design The growing demand for transparency about the efficacy of healthcare has accelerated the use of Patient‐Reported Outcome Measures (PROMs), but their integration into daily practice is challenging. This observational study describes how the Septoplasty Healthcare Monitor (SHM) addresses these challenges and highlights the ...
Victor S. van Dam, Diako Berzenji, Floris V. W. J. van Zijl, Martijn A. H. Oude Voshaar, Bernd Kremer, Frank R. Datema   +5 more
wiley   +1 more source

Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein. [PDF]

Elife
Waki K, Tani H, Kawahara E, Saga Y, Shimada T, Yamazaki E, Koike S, Morinaga Y, Isobe M, Kurosawa N.   +9 more
europepmc   +1 more source

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

Cell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang   +10 more
wiley   +1 more source

Intranasal administration of angiotensin receptor shRNA to brain lowers blood pressure in spontaneously hypertensive rats. [PDF]

Biomed Pharmacother
Lamptey RNL, Sun C, Singh J.
europepmc   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Intranasal Administration of the Combination of Dextro-Ketamine and Dexmedetomidine for Treatment of Diabetic Neuropathic Pain in Rats. [PDF]

J Pain Res
Sudo SZ, Montagnoli TL, Dematté BE, Santos AD, Trachez MM, Gubert F, Mendez-Otero R, Zapata-Sudo G.   +7 more
europepmc   +1 more source

Perspectives on Pertussis Prevention

Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Suppression of Indoleamine 2,3‐Dioxygenase Enhances Immune Responses to the Therapeutic Vaccine for Chronic Hepatitis B

Hepatology Research, EarlyView.
Indoleamine 2,3‐dioxygenase (IDO) activity modulates immune responses to the therapeutic HBV vaccine NASVAC. Genetic or pharmacological suppression of IDO enhanced vaccine efficacy in mice, and lower serum kynurenine levels predicted favorable responses in humans, suggesting IDO as both a therapeutic target and a biomarker.
Yohei Shirakami, Soranobu Ninomiya, Takayasu Ideta, Ayumu Kanbe, Toshihide Maeda, Daisuke Minowa, Daisuke Taguchi, Masaya Kubota, Hiroyasu Sakai, Kenji Imai, Yasuko Yamamoto, Hiroyasu Ito, Kuniaki Saito, Osamu Yoshida, Yoichi Hiasa, Masahito Shimizu   +15 more
wiley   +1 more source

Single Intranasal Administration of Ucn3 Affects the Development of PTSD Symptoms in an Animal Model. [PDF]

Int J Mol Sci
Tillinger A, Zvozilová A, Mach M, Horváthová Ľ, Dziewiczová L, Osacká J.   +5 more
europepmc   +1 more source