Results 211 to 220 of about 65,548 (298)

Intranasal Administration of KCNN2 Blocking Peptide Improves Deficits in Cognitive Flexibility in Mouse Model of Fetal Alcohol Spectrum Disorders. [PDF]

Int J Neuropsychopharmacol
Mohammad S, Wang L, Torii M, Hashimoto-Torii K.   +3 more
europepmc   +1 more source

Perspectives on Pertussis Prevention

Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Retrospective case series of two‐stage folded paramedian forehead flap nasal reconstruction without cartilage grafts

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Full‐thickness nasal defects of the tip, soft triangle, and ala are commonly reconstructed using a paramedian forehead flap with cartilage grafts or an epithesis. However, these approaches may be associated with donor‐site morbidity and psychological burden.
Conrad Hempel, Viktor Schnabel, Jan‐Christoph Simon, Sonja Grunewald   +3 more
wiley   +1 more source

Intranasal administration of neural stem cell-derived extracellular vesicles prevents cognitive decline in both male and female 3×Tg-AD mice by dampening neuroinflammation and epigenetically regulating amyloid β metabolism. [PDF]

Alzheimers Res Ther
Natale F, Dellaria A, Nifo Sarrapochiello I, Leone L, Spinelli M, Rinaudo M, Garofalo N, Grassi C, Fusco S.   +8 more
europepmc   +1 more source

Hamman's crunch—A pathognomonic sign of pneumomediastinum

Equine Veterinary Education, EarlyView.
Summary Pneumomediastinum, particularly spontaneous pneumomediastinum, is uncommon and presents a diagnostic challenge. In human medicine, auscultation of Hamman's crunch, a crepitant, crunching noise, audible over the cardiac region in synchrony with the heartbeat, is considered pathognomonic for pneumomediastinum.
S. McCullagh, C. R. Daniel, J. A. Keen, N. J. Parkinson, B. C. McGorum   +4 more
wiley   +1 more source

Neurotoxic and some systemic effects of cadmium oxide nanoparticles following their subchronic intranasal administration to rats: experimental data analysis. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Sutunkova MP, Minigalieva IA, Shabardina LV, Shelomentsev IG, Labzova AK, Sakhautdinova RR, Toropova LV.   +6 more
europepmc   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Therapeutic Effects of Intranasal Administration of Mesenchymal Stem Cell-Derived Secretome in Rats Exposed to Chronic Unpredictable Mild Stress. [PDF]

Pharmaceutics
Ávila A, Riveros ME, Adasme S, Guevara C, Del Rio R, Ortiz FC, Leibold N, Ezquer F.   +7 more
europepmc   +1 more source

The pharmacology of gepants in migraine: A scoping review on mechanisms, clinical applications, and combination strategies

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Calcitonin gene‐related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, novel CGRP receptor antagonists, has expanded therapeutic options for both acute and preventive treatment. This scoping review aims to synthesize current evidence on the pharmacology, clinical applications, safety ...
Luigi Francesco Iannone, Marcello Silvestro, Antonio Munafò, Marina Romozzi, Pierangelo Geppetti, Antonio Russo   +5 more
wiley   +1 more source

Novel nanostructured lipid carriers with lurasidone hydrochloride for intranasal administration for improved bioavailability. [PDF]

Ther Deliv
Kadam T, Agrawal S, Shetty S.
europepmc   +1 more source