Results 221 to 230 of about 96,176 (305)

Reconstruction of native cellular microanatomy in a novel bioengineered full thickness human nasal mucosal construct

Journal of Anatomy, EarlyView.
Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury, Bethany Dickson, Nicola Curtis, David Bunton, Kirsty Goncalves, Stefan Przyborski   +5 more
wiley   +1 more source

Hyaluronic Acid-Based Hybrid Nanoparticles as Promising Carriers for the Intranasal Administration of Dimethyl Fumarate. [PDF]

Int J Nanomedicine
Serri C, Piccioni M, Guarino V, Santonicola P, Cruz-Maya I, Crispi S, Di Cagno MP, Ferraro L, Dalpiaz A, Botti G, Giunchedi P, Rassu G, Gavini E.   +12 more
europepmc   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Impact of Intranasal Administration of Fresh Breast Milk in Very Low Birth Weight Infants With Germinal Matrix-Intraventricular Hemorrhage. [PDF]

Cureus
Sonmez Demir G, Ozdemir OM, Turgut M, Pekal Y, Koyuncu E, Güngör O, Ergin H.   +6 more
europepmc   +1 more source

Psychogenic polydipsia in dogs – a review of pathogenesis, diagnosis and treatment

Journal of Small Animal Practice, EarlyView.
Polyuria and polydipsia represent a common clinical presentation in dogs and may result from numerous disorders affecting different body systems. Compulsive water consumption is characteristic of psychogenic polydipsia, a primary polydipsia disorder rooted in neurologic, behavioural or environmental factors.
G. Pavlovsky
wiley   +1 more source

Association Between Perioperative Sleep Disorders and Post‐Operative Delirium in Cardiac Surgeries: A Systematic Review and Meta‐Analysis

Journal of Sleep Research, EarlyView.
Overview of studies included in the systematic review investigating the association between perioperative sleep disorders (PSD) and postoperative delirium (POD) in patients undergoing cardiac surgery. ABSTRACT Post‐operative delirium (POD) is an acute deterioration in cognitive function and highly prevalent after cardiac surgery (CS; up to 55 ...
Hesam Varpaei, Pallav Deka, Lorraine B. Robbins, Kousha Farhadi, Mathew Reeves, Fabrice Mowbray, Stuart F. Quan   +6 more
wiley   +1 more source

Intranasal administration of recombinant human BDNF as a potential therapy for some primary headaches. [PDF]

J Headache Pain
Greco R, Francavilla M, Facchetti S, Demartini C, Zanaboni AM, Antonangeli MI, Maffei M, Cattani F, Aramini A, Allegretti M, Tassorelli C, De Filippis L.   +11 more
europepmc   +1 more source

Comparative Pharmacokinetics of Intranasal or Intramuscular Atipamezole in Unsedated Dogs and Efficacy for Reversal of Xylazine Sedation

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The objectives of this study were to evaluate ATIP pharmacokinetics (PK) in healthy Beagle dogs after IM and IN dosing (Phase I), and to compare the rate of reversal of IM versus IN routes for xylazine (XYL) sedation (Phase II). This study was comprised of two sequential, randomized, crossover experiments. The initial PK study dosed ATIP by IN
Vanessa E. Cowan, Vanessa R. Mitcham, Deborah L. Michel, Chloe Lyons, Juliet Kennedy, Yoana C. Reyes Morales, Jennifer M. Loewen, Alan L. Chicoine   +7 more
wiley   +1 more source

Intranasal administration of <i>Ganoderma lucidum</i>-derived exosome-like nanovesicles ameliorates cognitive impairment by reducing inflammation in a mouse model of Alzheimer's disease. [PDF]

Front Pharmacol
Mi X, Ruan X, Lin R, Huang S, Cai P, Chen X, Liao J, Dai X.   +7 more
europepmc   +1 more source

The Efficacy of Pharmacotherapy Intervention on Anthropometric Outcomes in Survivors of Childhood Brain Tumors: An Updated Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Introduction Many survivors of childhood brain tumors face long‐term adverse health outcomes like obesity. Uncertainties surround the effect of interventions to manage obesity‐related outcomes in survivors of childhood brain tumors. The goal of this updated systematic review and meta‐analysis was to provide the best estimate of the treatment ...
David Hart, Lawrence Mbuagbaw, Joseph Beyene, Marwa Akola, Sarah Burrow, M. Constantine Samaan, Lehana Thabane, Adam Fleming, Donna L. Johnston, Shahrad R. Rassekh, Laura Banfield, Russell J. de Souza   +11 more
wiley   +1 more source