Results 21 to 30 of about 1,950,206 (296)

Comparative evaluation of two intranasal forms of Curcumin: Quantitation and impact on mouse model of asthma

Phytomedicine Plus, 2023
Aim of the study: Present study aimed to investigate impact of two different intranasal forms of curcumin on mouse model of asthma and detection of its absorption after different time points of administration.
Payal Singh, Ruchi Chawla, Ajai Kumar Pandey, J.K. Mishra, Rashmi Singh   +4 more
doaj   +1 more source

Pharmacokinetic Study of Intranasal Dexamethasone and Methylprednisolone Compared with Intravenous Administration: Two Open-Label, Single-Dose, Two-Period, Two-Sequence, Cross-Over Study in Healthy Volunteers

Pharmaceutics, 2022
Dexamethasone (DXM) and methylprednisolone (MEP) are potent glucocorticoids used to control several inflammatory conditions. Evidence of delayed DXM reaching the central nervous system (CNS) as well as tachyphylaxis and systemic, undesirable side effects
Graciela Cárdenas, Raúl J. Bobes, Gladis Fragoso, Nicolas I. Pérez-Osorio, Marisela Hernández, Alejandro Espinosa, Agnes Fleury, José Flores, The Revival Project Consortium, Juan Pedro Laclette, Edda Sciutto, Helgi Jung-Cook   +11 more
doaj   +1 more source

Transient Facial Nerve Paralysis (Bell's Palsy) following Intranasal Delivery of a Genetically Detoxified Mutant of Escherichia coli Heat Labile Toxin. [PDF]

, 2009
BACKGROUND: An association was previously established between facial nerve paralysis (Bell's palsy) and intranasal administration of an inactivated influenza virosome vaccine containing an enzymatically active Escherichia coli Heat Labile Toxin (LT ...
Kromann Ingrid, Woodrow, M, Novicki Deborah, Huo, Z, Del Giudice Giuseppe, Novicki, D, Rappuoli Rino, Thierry-Carstensen, B, Susan Barnett, Galiza, E, David J M Lewis, Rafaela Giemza, Andersen, P, Peter Andersen, Lewis David J. M., Barnett Susan, Maria Woodrow, Kromann, I, Giuseppe Del Giudice, Thierry-Carstensen Birgit, Giemza Rafaela, Ingrid Kromann, Andersen Peter, Lewis, DJ, Galiza Eva, Giemza, R, Huo Zhiming, Woodrow Maria, Deborah Novicki, Eva Galiza, Birgit Thierry-Carstensen, Rino Rappuoli, Del Giudice, G, Rappuoli, R, Barnett, S, Zhiming Huo   +35 more
core   +1 more source

Rapid and Widespread Distribution of Intranasal Small Extracellular Vesicles Derived from Mesenchymal Stem Cells throughout the Brain Potentially via the Perivascular Pathway

Pharmaceutics, 2023
Intranasal administration is a promising strategy to enhance the delivery of the sEVsomes-based drug delivery system to the central nervous system (CNS).
Weiwei Shen, Tongyao You, Wenqing Xu, Yanan Xie, Yingzhe Wang, Mei Cui   +5 more
doaj   +1 more source

Effects of Topical Intranasal Doxycycline Treatment in the Rat Allergic Rhinitis Model [PDF]

Clinical and Experimental Otorhinolaryngology, 2014
ObjectivesAllergic rhinitis (AR) is a chronic upper respiratory tract disease that inflames the mucous membranes of the nose and occurs when circulating inflammatory cells including eosinophils and basophils migrate to and accumulate in the inflammation ...
Mehmet Ozgür Avincsal, Seda Ozbal, Ahmet Omer Ikiz, Cetin Pekcetin, Enis Alpin Güneri   +4 more
doaj   +1 more source

Pre-clinical study of protective potency of candidate recombinant live pertussis vaccine for intranasal administration

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
The aim of present research is studying of protective potency of candidate recombinant live pertussis vaccine (RLPV) for intranasal administration.Materials and methods.
L. N. Sinyashina, E. G. Semin, A. Yu. Medkova, R. A. Syundyukova, G. I. Karataev   +4 more
doaj   +1 more source

Intranasal calcitonin gene-related peptide administration impairs fear memory retention in mice through the PKD/p-HDAC5/Npas4 pathway

Scientific Reports, 2022
The calcitonin gene-related peptide (CGRP) suppresses fear memory retention in mice. Although intracerebroventricular administration of CGRP alters the fear memory processes, making it a promising therapeutic strategy for post-traumatic stress disorder ...
Narumi Hashikawa-Hobara, Yoshikazu Yoneyama, Kyoushiro Fujiwara, Naoya Hashikawa   +3 more
doaj   +1 more source

Feasibility of Catalpol Intranasal Administration and Its Protective Effect on Acute Cerebral Ischemia in Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms

Drug Design, Development and Therapy, 2022
Jinghui Wang,1 Yuhua Zhang,2 Meifeng Zhang,1 Si Sun,1 Yang Zhong,1 Lei Han,1 Yitong Xu,1 Dong Wan,3 Junhui Zhang,4 Huifeng Zhu1 1College of Pharmaceutical Sciences & College of Chinese Medicine, Southwest University, Chongqing, 400715, People’s Republic ...
Wang J, Zhang Y, Zhang M, Sun S, Zhong Y, Han L, Xu Y, Wan D, Zhang J, Zhu H   +9 more
doaj  

Marketing research on intranasal medicines of domestic market

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Modern development of biopharmaceutical research in world science and practice promotes the use of new dosage forms or administration routes of active substances in the human body.
B. S. Burlaka, N. M. Chervonenko, I. F. Belenichev   +2 more
doaj   +1 more source

Intranasal Administration of Sugarcane Ash Causes Chronic Kidney Disease in Rats Supplemental Material

, 2023
Supplemental Figures and table for Intranasal Administration of Sugarcane Ash Causes Chronic Kidney Disease in Rats ...
Jared M. Brown (456099), Bernardo Rodriguez-Iturbe (124875), Arthur Stem (12342874), Makoto Miyazaki (316683), Fumihiko Sasai (10468173), Manuel Urra (15281848), Jacob Fox (5366204), Stephen Brindley (3426563), Julia Wijkström (4919239), Ramon Garcia-Trabanino (12251044), Richard J. Johnson (8544378), Carlos A. Roncal-Jimenez (119931), Magdalena Madero (12343027), Gabriela Garcia (119921), Jaime Butler-Dawson (5798078), Keegan L Rogers (12342912), Shinobu Miyazaki-Anzai (631791), L. Gabriela Sánchez-Lozada (5683976), annika@ki.se wernerson (6110334), Gabriel Cara-Fuentes (3949763)   +19 more
core   +1 more source