Results 51 to 60 of about 2,191,985 (278)

Intranasal administration of allergen increases specific IgE whereas intranasal omalizumab does not increase serum IgE levels : a pilot study [PDF]

, 2018
Background: Administration of the therapeutic anti-IgE antibody omalizumab to patients induces strong increases in IgE antibody levels. Objective: To investigate the effect of intranasal administration of major birch pollen allergen Bet v 1, omalizumab ...
Bischoff, Cameron, Chan, Chanez, Christianson, Chu, Dema, Eckl-Dorna, Egger, Egger, Gevaert, Ghetie, Gieras, Hauswirth, Hayashi, Humbert, Ishizaka, Jabara, Jardieu, Kaplan, Katona, KleinJan, Laffer, Lawrence, Lowe, Lupinek, MacGlashan, Mizuma, Naclerio, Nakamura, Narayanan, Niederberger, Noga, Noga, Ota, Platts-Mills, Steinberger, Stokes, Valent   +38 more
core   +1 more source

Cochleates derived from Vibrio cholerae O1 proteoliposomes : The impact of structure transformation on mucosal immunisation [PDF]

, 2012
Cochleates are phospholipid-calcium precipitates derived from the interaction of anionic lipid vesicles with divalent cations. Proteoliposomes from bacteria may also be used as a source of negatively charged components, to induce calcium-cochleate ...
Adriana Callicó, Alexander B. Mullen, Bárbara Cedré, Caridad Zayas, David Mckee, Gunnar F. Kaufmann, José L. Pérez, Luis García, Oliver Pérez, Reinaldo Acevedo, Valerie A. Ferro   +10 more
core   +11 more sources

Marketing research on intranasal medicines of domestic market

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Modern development of biopharmaceutical research in world science and practice promotes the use of new dosage forms or administration routes of active substances in the human body.
B. S. Burlaka, N. M. Chervonenko, I. F. Belenichev   +2 more
doaj   +1 more source

Electrocardiogram Assessment in Chough (Pyrrhocorax pyrrhocorax) Following Intranasal Administration of Anesthetics [PDF]

Iranian Journal of Veterinary Surgery, 2017
Objective- The objective of the present study was to define electrocardiographic data following intranasal administration of diazepam, midazolam and xylazine with or without Ketamine in Chough.Design- To determine the heart effects of anesthetics in ...
Majid Taati, Abbas Raisi
doaj   +1 more source

Shortcut Approaches to Substance Delivery into the Brain Based on Intranasal Administration Using Nanodelivery Strategies for Insulin

Molecules, 2020
The direct delivery of central nervous system (CNS) drugs into the brain after administration is an ideal concept due to its effectiveness and non-toxicity.
T. Tashima
semanticscholar   +1 more source

Pharmacokinetics of Cannabidiol Following Intranasal, Intrarectal, and Oral Administration in Healthy Dogs

Frontiers in Veterinary Science, 2022
The therapeutic potential of cannabidiol (CBD), a non-psychtropic component of the Cannabis sativa plant, is substantiated more and more. We aimed to determine the pharmacokinetic behavior of CBD after a single dose via intranasal (IN) and intrarectal ...
D. Polidoro, R. Temmerman, M. Devreese, Marios Charalambous, L. Ham, I. Cornelis, B. Broeckx, P. Mandigers, Andrea Fischer, J. Storch, S. Bhatti   +10 more
semanticscholar   +1 more source

Efficacy of intranasal administration of artesunate in experimental cerebral malaria [PDF]

, 2014
BACKGROUND: Improving management of patients suffering from cerebral malaria is needed to reduce the devastating mortality and morbidity of the disease in endemic areas.
Adeline Lavoignat, Anne Marijon, Anne-Lise Bienvenu, Anthony Fourier, Coralie Bringer, Guillaume Bonnot, Marie-Claude Gagnieu, Stéphane Picot   +7 more
core   +2 more sources

Pharmacometric Modeling of the Impact of Azelastine Nasal Spray on SARS-CoV-2 Viral Load and Related Symptoms in COVID-19 Patients

Pharmaceutics, 2022
The histamine-1 receptor antagonist azelastine was recently found to impact SARS-CoV-2 viral kinetics in a Phase 2 clinical trial (CARVIN). Thus, we investigated the relationship between intranasal azelastine administrations and viral load, as well as ...
Christiane Dings, Peter Meiser, Frank Holzer, Michael Flegel, Dominik Selzer, Eszter Nagy, Ralph Mösges, Jens Peter Klussmann, Thorsten Lehr   +8 more
doaj   +1 more source

Recent Advances in Intranasal Administration for Brain-Targeting Delivery: A Comprehensive Review of Lipid-Based Nanoparticles and Stimuli-Responsive Gel Formulations

International Journal of Nanomedicine
Addressing disorders related to the central nervous system (CNS) remains a complex challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry of external substances into the brain tissue.
Jain Koo, Chaemin Lim, Kyung Taek Oh
semanticscholar   +1 more source

The pharmacokinetics of intranasal droperidol in volunteers characterised via population modelling

SAGE Open Medicine, 2018
Background: Droperidol is used parenterally to treat nausea and vomiting, migraine and acute behavioural disturbance. Intranasal use is not reported for droperidol.
Isabelle Cooper, Cornelia B Landersdorfer, Ashley Gordon St John, Andis Graudins   +3 more
doaj   +1 more source