Results 41 to 50 of about 3,438,764 (296)

Immunological backbone of uveal melanoma: is there a rationale for immunotherapy? [PDF]

, 2019
No standard treatment has been established for metastatic uveal melanoma (mUM). Immunotherapy is commonly used for this disease even though UM has not been included in phase III clinical trials with checkpoint inhibitors.
Alessandra Cassano, Apte, Bill, Blom, Brigida Anna Maiorano, De Vries, Durie, Emilio Bria, Ericsson, Ernesto Rossi, Giampaolo Tortora, Gianluigi Petrone, Giovanni Schinzari, Guido Rindi, Ilaria Grazia Zizzari, Lagouros, Makitie, Maria Antonietta Blasi, Maria Grazia Sammarco, Marianna Nuti, Monica Maria Pagliara, Shaw, Sohn, Vincenzo Fiorentino, Whelchel   +24 more
core   +1 more source

Epiregulin, epigen and betacellulin antibodies and axial elongation in young guinea pigs with lens-induced myopization

BMC Ophthalmology, 2022
Background To examine an effect of intravitreally applied antibodies against epidermal growth factor family members, namely epiregulin, epigen and betacellulin, on ocular axial elongation.
Li Dong, Rui-Heng Zhang, Wen-Da Zhou, Yi-Fan Li, He-Yan Li, Hao-Tian Wu, Xu-Han Shi, Jost. B. Jonas, Wen-Bin Wei   +8 more
doaj   +1 more source

Circulating tumor DNA tracking through driver mutations as a liquid biopsy-based biomarker for uveal melanoma

Journal of experimental & clinical cancer research : CR, 2021
Uveal melanoma (UM) is the most common intraocular tumor in adults. Despite good primary tumor control, up to 50% of patients develop metastasis, which is lethal.
Prisca Bustamante, Thupten Tsering, J. Coblentz, Christina Mastromonaco, M. Abdouh, Cristina Fonseca, R. Proença, Nadya Blanchard, Claude Laure Dugé, Rafaella Atherino Schmidt Andujar, E. Youhnovska, M. Burnier, S. Callejo, J. Burnier   +13 more
semanticscholar   +1 more source

Global, regional, and national prevalence, disability adjusted life years, and time trends for refraction disorders, 1990–2019: findings from the global burden of disease study 2019

BMC Public Health, 2021
Background To evaluate global burden of refraction disorders by year, age, region, gender, socioeconomic status and other national characteristics in terms of disability adjusted life years (DALYs) and prevalence from Global Burden of Disease (GBD) study
He-Yan Li, Yue-Ming Liu, Li Dong, Rui-Heng Zhang, Wen-Da Zhou, Hao-Tian Wu, Yi-Fan Li, Ya-Xing Wang, Wen-Bin Wei   +8 more
doaj   +1 more source

Validation of the Relationship Between Iris Color and Uveal Melanoma Using Artificial Intelligence With Multiple Paths in a Large Chinese Population

Frontiers in Cell and Developmental Biology, 2021
Previous studies have shown that light iris color is a predisposing factor for the development of uveal melanoma (UM) in a population of Caucasian ancestry.
Haihan Zhang, Yueming Liu, Kai Zhang, Shiqi Hui, Yu Feng, Jingting Luo, Yang Li, Wenbin Wei   +7 more
doaj   +1 more source

False‑positive technetium‑99m methylene diphosphonate bone scan activity in the orbit in a patient with a history of breast carcinoma [PDF]

, 2018
Metastasis of breast carcinoma to the orbit is an uncommon entity and carries a poor prognosis. This case report presents false-positive technetium-99m methylene diphosphonate activity in the right orbit of a patient with a history of a primary breast ...
Bonnet, Sarah E., Palko, Joel R.
core   +2 more sources

Hydrostatic pressure does not cause detectable changes to survival of human retinal ganglion [PDF]

, 2015
Purpose: Elevated intraocular pressure (IOP) is a major risk factor for glaucoma. One consequence of raised IOP is that ocular tissues are subjected to increased hydrostatic pressure (HP).
Amal Aldarwesh, Andrew Osborne, B Coudrillier, C Zhang, CF Burgoyne, CF Burgoyne, Claire Everitt, CR Ethier, David C. Broadway, G Morris, G Tezel, G Tezel, Glyn Chidlow, HA Quigley, IA Sigal, J Vandesompele, JC Downs, JC Dreixler, Jeremy D. Rhodes, Julie Sanderson, L Mester, LK Mao, M Inatani, M Kikuchi, MC Leske, MC Leske, N Niyadurupola, N Niyadurupola, NN Osborne, RM Sappington, RM Sappington, S Resnikoff, S Roth, V Resta, VT Ribas, Y Lei   +35 more
core   +7 more sources

Intraocular medulloepithelioma

Definitions, 2020
Intraocular medulloepithelioma is a rare eye tumor characterized by a white, gray or yellow-colored cystic mass that arises from the primitive neuroectodermal, nonpigmented epithelium of the ciliary body, or occasionally from the optic nerve, optic disc,

semanticscholar   +1 more source

In-vivo sclera thickness measurements in experimental myopia of guinea pigs

BMC Ophthalmology
The sclera is the target organ of axial elongation during myopia onset and progression. Visualizing the sclera in-vivo is important for monitoring the dynamic changes of the sclera remodeling in experimental myopia.
Ruiheng Zhang, Chuyao Yu, Li Dong, Yitong Li, Xuhan Shi, Haotian Wu, Wenda Zhou, Heyan Li, Wenbin Wei   +8 more
doaj   +1 more source

Correlation of the history of stroke and the retinal artery occlusion: a nested case-control study [PDF]

International Journal of Ophthalmology, 2020
"AIM: To analyze the systemic factors including stroke history related to the retinal artery occlusion (RAO). METHODS: Patients with an exact diagnosis of RAO in the medical database of the Kailuan Corporation were identified as the case group.
Yue-Yan Xiao, Wen-Bin Wei, Ya-Xing Wang, Ai-Dong Lu, Shuo-Hua Chen, Lu Song, Shou-Ling Wu   +6 more
doaj   +1 more source