Results 91 to 100 of about 49,659 (173)
Nestinþ cells direct inflammatory cell migration in atherosclerosis [PDF]
, 2016 Atherosclerosis is a leading death cause. Endothelial and smooth muscle cells participate in atherogenesis, but it is unclear whether other mesenchymal cells contribute to this process. Bone marrow (BM) nestinþ cells cooperate with endothelial cells in
Andrés, Vicente +6 more
core
The role of platelet microvesicles in intercellular communication. [PDF]
, 2016 In recent years, there has been exponential growth in the interest in microvesicles, which is reflected by the number of publications. Initially referred to as platelet dust by Peter Wolf in 1967, platelet microvesicles (PMV) are now recognized as ...
Edelstein, Leonard C.
core +2 more sources
Emerging understandings of the role of exosomes in atherosclerosis
Journal of Cellular Physiology, Volume 240, Issue 1, January 2025.Abstract Atherosclerosis remains a major contributor to cardiovascular disease, the leading cause of global morbidity and mortality. Despite the elucidation of several molecular, biochemical, and cellular aspects that contribute to the etio‐pathogenesis of atherosclerosis, much remains to be understood about the onset and progression of this disease ...
Zena Wehbe +6 more
wiley +1 more source
Biomarkers of atherosclerosis and the potential of MRI for the diagnosis of vulnerable plaque. [PDF]
, 2007 Atherosclerosis is a chronic inflammatory vascular disease. As it is an inflammation process, many cellular and molecular events are involved at each step of the progression of atherosclerosis from an early fatty streak lesion to a highly dangerous ...
Canet-Soulas, Emmanuelle +1 more
core +5 more sources
Lonafarnib is a potential inhibitor for neovascularization. [PDF]
PLoS ONE, 2015 Atherosclerosis is a common cardiovascular disease that involves the build-up of plaque on the inner walls of the arteries. Intraplaque neovacularization has been shown to be essential in the pathogenesis of atherosclerosis.
Linlin Sun +6 more
doaj +1 more source
Recent advances in mitochondria‐targeting theranostic agents
Exploration, Volume 4, Issue 4, August 2024.Possessing diagnostic imaging and therapeutic functions, mitochondria‐targeted theranostic agents can significantly optimize the treatment process and promote precision medicine. This review summarizes the research progress on these agents and the commonly used diagnostic modalities and therapeutic strategies.
Kun Qian +4 more
wiley +1 more source
Molecular imaging of inflammation and intraplaque vasa vasorum: A step forward to identification of vulnerable plaques? [PDF]
, 2010 Current developments in cardiovascular biology and imaging enable the noninvasive molecular evaluation of atherosclerotic vascular disease. Intraplaque neovascularization sprouting from the adventitial vasa vasorum has been identified as an independent ...
Daemen, MJAP +7 more
core +8 more sources
Hypoxia, angiogenesis and atherogenesis [PDF]
, 2017 The balance between vascular oxygen supply and metabolic demand for oxygen within the vasculature is normally tightly regulated. An imbalance leads to hypoxia and a consequential cascade of cellular signals that attempt to offset the effects of hypoxia ...
Ferns, Gordon, Heikal, Lamia
core +2 more sources
Advanced Science, Volume 11, Issue 26, July 10, 2024.This review describes and critically evaluates computational and biological models of atherosclerosis, focusing on the hemodynamics of occluded coronary arteries. It examines emerging strategies that integrate computational and biological models and explores the advances in imaging, biofabrication, single‐cell omics, and machine learning for model ...
Thao Nhu Anne Marie Vuong +8 more
wiley +1 more source
A new murine model of stress-induced complex atherosclerotic lesions
Disease Models & Mechanisms, 2013 SUMMARY The primary purpose of this investigation was to determine whether ApoE−/− mice, when subjected to chronic stress, exhibit lesions characteristic of human vulnerable plaque and, if so, to determine the time course of such changes.
Amir H. Najafi +14 more
doaj +1 more source