Results 61 to 70 of about 49,659 (173)

Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques

Frontiers in Neurology, 2023
Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation.
Zhiwei He, Jiaying Luo, Mengna Lv, Qingwen Li, Wei Ke, Xuan Niu, Zhaohui Zhang   +6 more
doaj   +1 more source

Angiogenesis-dependent and independent phases of intimal hyperplasia. [PDF]

, 2004
BACKGROUND: Neointimal vascular smooth muscle cell (VSMC) proliferation is a primary cause of occlusive vascular disease, including atherosclerosis, restenosis after percutaneous interventions, and bypass graft stenosis. Angiogenesis is implicated in the
Bhardwaj, S, De Muinck, E, Ferrara, N, Khurana, R, Martin, JF, Murakami, M, Simons, M, Yla-Herttuala, S, Zachary, I, Zhuang, Z   +9 more
core   +1 more source

Contrast-enhanced ultrasonography of the carotids [PDF]

Ultrasonography, 2015
Contrast-enhanced ultrasonography of the carotids has recently emerged as a complementary examination to conventional carotid Doppler ultrasonography. It is an examination providing improved visualization of the vascular lumen, more accurate and detailed
Vasileios Rafailidis, Georgios Pitoulias, Konstantinos Kouskouras, Dimitrios Rafailidis   +3 more
doaj   +1 more source

Ultrasonic transducer-guided electrochemical impedance spectroscopy to assess lipid-laden plaques [PDF]

, 2016
Plaque rupture causes acute coronary syndromes and stroke. Intraplaque oxidized low density lipoprotein (oxLDL) is metabolically unstable and prone to induce rupture.
Abiri, Parinaz, Ding, Yichen, Hsiai, Tzung, Li, Rongsong, Luo, Yuan, Ma, Jianguo, Ma, Teng, Packard, René R. Sevag, Shung, Kirk K., Tai, Yu-Chong, Zhou, Qifa   +10 more
core   +1 more source

Non-invasive vulnerable plaque imaging: how do we know that treatment works? [PDF]

, 2014
Atherosclerosis is an inflammatory disorder that can evolve into an acute clinical event by plaque development, rupture, and thrombosis. Plaque vulnerability represents the susceptibility of a plaque to rupture and to result in an acute cardiovascular ...
Brevetti L, Cuocolo A, Esposito G, Giugliano G, Mainolfi C, Perrino C, Sannino A, Scudiero F, Stabile E, Toscano E, Trimarco B   +10 more
core   +1 more source

Differential Features of Culprit Intracranial Atherosclerotic Lesions: A Whole-Brain Vessel Wall Imaging Study in Patients With Acute Ischemic Stroke. [PDF]

, 2018
BackgroundIntracranial atherosclerotic disease tends to affect multiple arterial segments. Using whole-brain vessel wall imaging, we sought to study the differences in plaque features among various types of plaques in patients with a recent unilateral ...
Bi, Xiaoming, Diniz, Marcio A, Fan, Zhaoyang, Gonzalez, Nestor R, Guo, Xiuhai, Ji, Xunming, Li, Debiao, Ma, Qingfeng, Song, Haiqing, Song, Shlee S, WISP Investigators, Wu, Fang, Yang, Qi   +12 more
core  

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, Volume 6, Issue 11, November 2025.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source

Relation between carotid vulnerable plaques and peripheral leukocyte: a case-control study of comparison utilizing multi-parametric contrast-enhanced ultrasound

BMC Medical Imaging, 2019
Background This study evaluates carotid vulnerable plaques using contrast-enhanced ultrasound (CEUS) and explores the relationship between vulnerable plaques and leukocytes. Methods Sixty-two symptomatic and 54 asymptomatic patients underwent CEUS.
Xianghong Luo, Wanbin Li, Yun Bai, Lianfang Du, Rong Wu, Zhaojun Li   +5 more
doaj   +1 more source

Orthopedic surgery increases atherosclerotic lesions and necrotic core area in ApoE-/- mice [PDF]

, 2016
Background and aims Observational studies show a peak incidence of cardiovascular events after major surgery. For example, the risk of myocardial infarction increases 25-fold early after hip replacement.
Chen, Cohen, Corrales-Medina, Dutta, Dutta, Gualandro, Hans W.M. Niessen, Hanson, Ilse P.A. Zethof, Janssen, Kaynar, King, Kleemann, Lalmohamed, Landesberg, Lars F.H. Theyse, Libby, Martine C. Morrison, Moore, Morrison, Naghavi, Paul A.J. Krijnen, Reid, Rianne van der Linden, Robert Kleemann, Santos-Gallego, Santos-Gallego, Santos-Gallego, Seimon, Smeeth, Tan, Thompson, Thompson, Van der Donckt, van Dijk, Virmani, Virmani, Wessel W. Fuijkschot, Yvo M. Smulders, Zhang   +39 more
core   +2 more sources

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9): The Multifaceted Biology, Diseases, and Pharmaceutical Interventions

MedComm, Volume 6, Issue 11, November 2025.
Summary of PCSK9 inhibitor mechanisms. PCSK9 inhibitors (PCSK9‐i) primarily lower LDL‐cholesterol (LDL‐C) by blocking PCSK9‐mediated degradation of hepatic LDL receptors (LDLR), enhancing LDL clearance. Beyond LDLR‐dependent effects, PCSK9‐i exert multiple benefits via LDLR‐independent pathways.
Jia Kuang, Lei Hao, Meibiao Zhang, Zhao Yang   +3 more
wiley   +1 more source