Results 11 to 20 of about 83,573 (199)
Background Intrathecal baclofen therapy can substantially improve symptoms in most patients with severe spasticity due to traumatic spinal cord injury, multiple sclerosis, or cerebral paresis.
Yasutaka Takagi +11 more
doaj +2 more sources
Status dystonicus resembling the intrathecal baclofen withdrawal syndrome: a case report and review of the literature [PDF]
Introduction Status dystonicus is a rare but life-threatening disorder characterized by increasingly frequent and severe episodes of generalized dystonia that may occur in patients with primary or secondary dystonia.
Muirhead William +2 more
doaj +3 more sources
Although intrathecal baclofen (ITB) therapy is an effective treatment for spasticity, it has several disadvantages and a risk of complications. We present six pediatric patients who suffered from unusual mechanical failures of intrathecal baclofen pump ...
J. Gburek-Augustat +7 more
semanticscholar +2 more sources
Oral baclofen has long been a mainstay in the management of spasticity. This review looks at the clinical evidence for the efficacy and safety of oral baclofen in patients with spasticity of any origin or severity, to determine whether there is a ...
P. Ertzgaard, C. Campo, A. Calabrese
semanticscholar +2 more sources
Intrathecal baclofen therapy in patients with spastic paraplegia: retrospective evaluation of pretreatment drugs, test dosage, dose increments and final therapy [PDF]
Introduction: Intrathecal baclofen therapy (ITB) is an effective alternative for severe generalized spasticity after unsuccessful oral spasmolytic therapy. Research question: What degree of severity, type and duration of pretreatment indicated ITB?
Stephan Kurz +4 more
doaj +2 more sources
A pediatric case of generalized tetanus treated with intrathecal baclofen
Introduction Generalized tetanus from Clostridium tetani infections is rare in the United States due to widespread use of tetanus toxoid-containing vaccines, and management of these critically ill patients can be challenging.
Elizabeth M. Silver +3 more
doaj +2 more sources
The Effect of Intrathecal Baclofen in Dyskinetic Cerebral Palsy: The IDYS Trial
Intrathecal baclofen treatment is used for the treatment of dystonia in patients with severe dyskinetic cerebral palsy; however, the current level of evidence for the effect is low.
L. Bonouvrié +4 more
semanticscholar +3 more sources
Characteristics of Changes in Intrathecal Baclofen Dosage over Time due to Causative Disease [PDF]
Intrathecal baclofen (ITB) therapy effectively treats spasticity caused by brain or spinal cord lesions. However, only a few studies compare the course of treatment for different diseases. We investigated the change in daily dose of baclofen per year and
Yuki KIMOTO +14 more
doaj +2 more sources
Spasticity may cause immobility, prostration, chronic pain, bedsores, infections, thrombosis and pneumonia; the purposes of its treatment are to control pain, improve mobility and quality of life, and reincorporate the patient to its daily activities by ...
Cáceres-Jerez, Luz Elena +2 more
doaj +2 more sources
Continuous intrathecal baclofen delivery in severely disabling spasticity [PDF]
Background/Aim. Spasticity is the consequence of several clinical conditions including cerebral palsy, brain injury, spinal cord injury, multiple sclerosis, aneurysm bleeding, and some other neurological disorders.
Simsek Hakan +4 more
doaj +2 more sources

