Results 11 to 20 of about 64,466 (204)

Super analgesia of intrathecal morphine may be related to ABCB1 (MDR1) gene polymorphism

Journal of Pain Research, 2018
Wangjun Qin,1,* Botao Liu,2,* Ang Deng,1 Ying Liu,1 Xianglin Zhang,1 Lei Zhang1 1Department of Pharmacy, China-Japan Friendship Hospital, Beijing, China; 2Department of Pain Management, China-Japan Friendship Hospital, Beijing, China *These authors ...
Qin WJ, Liu BT, Deng A, Liu Y, Zhang XL, Zhang L   +5 more
doaj   +1 more source

The Clinical Effects of Intrathecal Morphine in Contemporary Surgery [PDF]

, 2021
Intrathecal morphine has been used for analgesia for several decades, but lost popularity because there were alternative methods of analgesia which were more suitable.
Koning, Mark
core   +12 more sources

NMDA receptor antagonists attenuate intrathecal morphine-induced pruritus through ERK phosphorylation

Molecular Brain, 2018
Pruritus is the most common complication of intrathecal morphine; however, its exact molecular mechanism is unclear, and treatment is challenging. The analgesic effect of N-methyl-D-aspartate (NMDA) receptor antagonists and the morphine-associated ...
Le Shen, Weijia Wang, Siyu Li, Jing Qin, Yuguang Huang   +4 more
doaj   +2 more sources

Efficacy and Safety of Ropivacaine Addition to Intrathecal Morphine for Pain Management in Intractable Cancer [PDF]

Mediators of Inflammation, 2015
Objective. Although intrathecal drug infusion has been commonly adopted for terminal cancer pain relief, its adverse effects have made many clinicians reluctant to employ it for intractable cancer pain.
Ying Huang, Xihan Li, Tong Zhu, Jian Lin, Gaojian Tao   +4 more
doaj   +2 more sources

Systematic Literature Review of Spinal Cord Stimulation in Patients With Chronic Back Pain Without Prior Spine Surgery

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective Low back pain is the leading cause of disability worldwide and one of the most common reasons for seeking healthcare. Despite numerous care strategies, patients with low back pain continue to exhibit poor outcomes. Spinal cord stimulation (SCS) is an evidence‐based therapeutic modality for patients with failed back surgery syndrome ...
Jan M. Eckermann, Julie G. Pilitsis, Christopher Vannaboutathong, Belinda J. Wagner, Rose Province‐Azalde, Markus A. Bendel   +5 more
wiley   +1 more source

A double-blind, randomised, placebo-controlled trial comparing intrathecal bupivacaine with bupivacaine plus morphine to reduce delirium in patients with hip fractures—Salmon-Mind trial study protocol

BJA Open, 2023
Background: Surgical treatment of proximal femur fractures is complicated by postoperative delirium in about one-third of patients. Pain and opioid consumption are modifiable factors that may influence the incidence of delirium.1 An intrathecal injection
Aart Jan W. Teunissen, Mark V. Koning, Willem J. Liefers, Dawi v.d. Stap, Gert Roukema, Bart de Bruijn, Charlotte E. Teunissen, Seppe A. Koopman   +7 more
doaj   +1 more source

Intrathecal Morphine Injection for Postoperative Analgesia Following Gender-Affirming Pelvic Surgery: A Retrospective Case-Control Study [PDF]

, 2023
Background Gender-affirming pelvic surgery (GAPS) can be associated with significant postoperative pelvic pain. Given the lack of available peripheral nerve blocks to the perineum, intrathecal morphine (ITM) injection could offer a potent analgesic ...
Sztain, Jacklynn F, Sztain, Jacklynn, Swisher, Matthew W, Anger, Jennifer T, Tsuda, Paige S, Dolendo, Isabella M, Alexander, Brenton S, Said, Engy T   +7 more
core   +1 more source

Impact of Intrathecal Fentanyl on Hospital Outcomes for Patients Undergoing Primary Total Hip Arthroplasty With Neuraxial Anesthesia

Arthroplasty Today, 2021
Background: Intrathecal opioids have been used to reduce pain after total joint arthroplasty; however, the utility of these drugs is disputed. We examined the impact of eliminating intrathecal fentanyl on outcomes for patients undergoing direct anterior ...
McKayla Kelly, BS, Justin Turcotte, PhD, MBA, Jacob Aja, PA-C, James MacDonald, MD, Paul King, MD   +4 more
doaj   +1 more source

Hypothermia With Paradoxical Symptoms: A Case Series of Cesarean Deliveries With Intrathecal Morphine

, 2023
Women receiving intrathecal morphine for cesarean delivery may experience hypothermia with paradoxical symptoms of sweating, nausea, and shivering. Despite being relatively rare in comparison to commonly experienced symptoms of perioperative hypothermia,
Judy Munday, Sonya Osborne, Kathryn Kynoch, Maffey, Simon, Osborne, Sonya, Munday, Judy, Victoria Steelman, Simon Maffey, Kynoch, Kathryn, Steelman, Victoria, Mary‐Anne Ramis, Ramis, Mary-Anne   +11 more
core   +1 more source

Side-Effect Profiles And Efficacy Of Low Dose Intrathecal Morphine Combine With Periarticular Injection In Elective Primary Unilateral Total Knee Arthroplasty

Orthopaedic Journal of Sports Medicine, 2020
Background: Total knee arthroplasty (TKA) is concerned as a severe postoperative pain procedure. Intrathecal morphine provides good analgesia but has many side effects such as nausea, vomiting, pruritus and respiratory depression.
Chompunoot Pathonsamit MD, Pruk Chaiyakit MD, Ittiwat Onklin MD   +2 more
doaj   +1 more source