Results 31 to 40 of about 18,654 (227)

Serious Adverse Events after a Single Shot of Intrathecal Morphine: A Case Series and Systematic Review

Pain Research and Management, 2022
Background. The dose of intrathecal morphine is important because of its narrow therapeutic range. Due to a compounding error, pharmacy-compounded, ready-to-use syringes contained 1 mg ml−1 morphine instead of the intended 50 mcg ml−1.
Mark V. Koning, Elmer Reussien, Beatrijs A. N. Vermeulen, Svenja Zonneveld, Elsbeth M. Westerman, Jurgen C. de Graaff, Bernard M. Houweling   +6 more
doaj   +1 more source

Efficacy of intrathecal morphine administration in pediatric patients undergoing selective dorsal rhizotomy

Journal of Pediatric Rehabilitation Medicine, 2023
PURPOSE: The purpose of this study was to evaluate the effectiveness of intrathecal morphine following selective dorsal rhizotomy in pediatric patients previously diagnosed with cerebral palsy.
Jared Pennington, Shawnelle Contini, Miraides Brown, Nupur Goel, Tsulee Chen   +4 more
doaj   +1 more source

Monoclonal antibody targeting mu-opioid receptor attenuates morphine tolerance via enhancing morphine-induced receptor endocytosis

Journal of Pharmaceutical Analysis, 2023
Morphine is a frequently used analgesic that activates the mu-opioid receptor (MOR), which has prominent side effects of tolerance. Although the inefficiency of morphine in inducing the endocytosis of MOR underlies the development of morphine tolerance ...
Jia-Jia Zhang, Chang-Geng Song, Miao Wang, Gai-Qin Zhang, Bin Wang, Xi Chen, Peng Lin, Yu-Meng Zhu, Zhi-Chuan Sun, Ya-Zhou Wang, Jian-Li Jiang, Ling Li, Xiang-Min Yang, Zhi-Nan Chen   +13 more
doaj   +1 more source

Contribution of Piezo2 to endothelium-dependent pain. [PDF]

, 2015
BackgroundWe evaluated the role of a mechanically-gated ion channel, Piezo2, in mechanical stimulation-induced enhancement of hyperalgesia produced by the pronociceptive vasoactive mediator endothelin-1, an innocuous mechanical stimulus-induced ...
Bogen, Oliver, Ferrari, Luiz F, Green, Paul, Levine, Jon D   +3 more
core   +2 more sources

Palonosetron versus ondansetron for prevention of nausea and vomiting after total abdominal hysterectomy under spinal anesthesia with intrathecal morphine: a double-blind, randomized controlled trial

BMC Anesthesiology, 2019
Background Hysterectomy is a widely performed surgery and neuraxial anesthesia with intrathecal morphine provides superior quality of recovery. Postoperative nausea and vomiting (PONV) is a frequent problem with intrathecal morphine use.
Guilherme Oliveira Campos, Marcelo de Jesus Martins, Gabriel Nascimento Jesus, Paulo Roberto Rios de Oliveira, Caio Nogueira Lessa, João Carlos Macêdo Fernandes de Oliveira Junior, Lucas Jorge Santana de Castro Alves, Rodrigo Leal Alves, Norma Sueli Pinheiro Módolo   +8 more
doaj   +1 more source

Controlled-release of opioids for improved pain management [PDF]

, 2016
The adequate treatment of pain remains one of the major medical challenges. Morphine and other opioid drugs are most commonly used to counteract moderate to severe pain, but they are also increasingly accessed by patients with chronic non-malignant pain.
Ballet, Steven, De Baerdemaeker, Andy, Hoogenboom, Richard, Madder, Annemieke, Martin, Charlotte, Poelaert, Jan   +5 more
core   +1 more source

Comparative study between doses of intrathecal morphine for analgesia after caesarean

Brazilian Journal of Anesthesiology, 2013
Background and objectives: Analgesia after caesarean section is important because postpartum women with pain have difficulty in mobility, which undermines breastfeeding. Intrathecal morphine provides adequate and prolonged analgesia after cesarean.
Francisco Amaral Egydio de Carvalho, Sérgio B. Tenório   +1 more
doaj   +1 more source

Comparative Efficacy of 3 Adjuvant Medications Used in Combination with Intrathecal Bupivacaine for Caesarian Section Anesthesia: A Randomized, Double-Blind Clinical Trial

Current Therapeutic Research, 2022
: Background: A number of different medications are used in combination with intrathecal bupivacaine for cesarean section anesthesia, but their relative efficacy has not been well established.
Reza Jouybar, MD, Zeinabsadat Fattahi Saravi, MD, Nazi Dehghani, MD, Sara Sadeghi, MD, Sahar Chehelgerdi Samani, MD, Zahra Esmaeilinezhad, MSc, Farzaneh Masihi, MSc, Naeimehosadat Asmarian, PhD   +7 more
doaj   +1 more source

Transient neurologic symptoms following spinal anesthesia with isobaric mepivacaine: A decade of experience at Toronto Western Hospital [PDF]

, 2018
Background: Transient neurologic symptoms (TNSs) can be distressing for patients and providers following uneventful spinal anesthesia. Spinal mepivacaine may be less commonly associated with TNS than lidocaine; however, reported rates of TNS with ...
Abdallah, Faraj W., Behboudi, Minou, Brull, Richard, MacFarlane, Alan, Sankar, Ashwin   +4 more
core   +2 more sources

Neuraxial opioids as analgesia in labour, caesarean section and hysterectomy: A questionnaire survey in Sweden [version 2; referees: 2 approved]

F1000Research, 2017
Background: Neuraxial opioids improve labour analgesia and analgesia after caesarean section (CS) and hysterectomy. Undesirable side effects and difficulties in arranging postoperative monitoring might influence the use of these opioids.
Anette Hein, Caroline Gillis-Haegerstrand, Jan G. Jakobsson   +2 more
doaj   +1 more source