Patient-controlled epidural Levobupicvacaine with or without Fentanyl for post-cesarean section pain relief [PDF]
, 2014 Purpose. The purpose of this study was to compare the analgesic properties of levobupivacaine with or without fentanyl for patient-controlled epidural analgesia after Cesarean section in a randomized, double-blinded study. Methods.
Chang, Hung-Chi +6 more
core +4 more sources
Intrathecal Morphine for Post-Thoracotomy Pain
Anesthesia & Analgesia, 1986 We wished to investigate possible differences in the duration of postoperative analgesia and the incidence of respiratory depression after the intrathecal injection in the lumbar area of 10 micrograms/kg morphine in hypobaric and hyperbaric solution for relief of post-thoracotomy pain.
J R, Gray +4 more
openaire +3 more sources
Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential
British Journal of Pharmacology, Volume 182, Issue 21, Page 5090-5118, November 2025.Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley +1 more source
Group III metabotropic glutamate receptors inhibit hyperalgesia in animal models of inflammation and neuropathic pain [PDF]
, 2007 International audienceGlutamate plays a key role in modulation of nociceptive processing. This excitatory amino acid exerts its action through two distinct types of receptors, ionotropic and metabotropic glutamate receptors (mGluRs).
Acher, Francine +5 more
core +4 more sources
CXCL10 Involvement in Vestibular Migraine via the PI3K/AKT Signaling Pathway
CNS Neuroscience &Therapeutics, Volume 31, Issue 11, November 2025.CXCL10 activates the PI3K/AKT signaling pathway, promoting the release of inflammatory factors, including IL‐1β, IL‐6, and TNF‐α, and is thus involved in the pathogenesis of VM. ABSTRACT Aims C‐X‐C motif chemokine ligand 10 (CXCL10) is a member of the CXC chemokine family, known as a classical pain‐related chemokine.
Mao‐mei Song +5 more
wiley +1 more source
Медицина болю, 2019 Background and Objectives: The most used of regional anesthesia technic is spinal anesthesia. Spinal anesthesia is an easier technic to get the depth and speed of nerve blockade.
Erwin Kresnoadi
doaj +1 more source
Calcium channel modulation as a target in chronic pain control [PDF]
, 2017 Neuropathic pain remains poorly treated for large numbers of patients and little progress has been made in developing novel classes of analgesics. To redress this issue, ziconotide (PrialtTM ) was developed and approved as a first in class synthetic ...
Dickenson, AH +2 more
core +1 more source
Repetitive single subarachnoid injections for trial administration of the intrathecal morphine pump in patients with intractable non-cancer pain -A case report- [PDF]
Korean Journal of Anesthesiology, 2011 Since the early 1980s, the implantable intrathecal drug pump (ITDP) has been used increasingly to manage chronic pain. Prior to making a decision to implant an ITDP, trial administration of the intrathecal (IT) drug should be performed to estimate the ...
Jae-Woo Lee +5 more
doaj +1 more source
Anesthesia for cystotomy in a dog with pancreatitis and a portosystemic shunt [PDF]
, 2010 A 21-month-old Cocker spaniel with a portosystemic shunt, a moderate thrombocytopenia and a history of pancreatitis, was anesthetized for a cystotomy to remove bladder polyps and stones.
Brearley, JC +3 more
core +1 more source
Treatments for spasticity and pain in multiple sclerosis: a systematic review [PDF]
, 2003 Objectives: To identify the drug treatments currently available for the management of spasticity and pain in multiple sclerosis (MS), and to evaluate their clinical and cost-effectiveness.
Beard, S.M., Hunn, A., Wight, J.
core +1 more source