Results 121 to 130 of about 35,236 (241)

An antisense oligonucleotide targeting the heat‐shock protein HSPB5 as an innovative therapeutic approach in pulmonary fibrosis

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 12, Page 2713-2729, June 2025.
Background and Purpose Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by fibroblast activation and abnormal accumulation of extracellular matrix in the lungs. We previously demonstrated the importance of the heat shock protein αB‐crystallin (HSPB5) in TGF‐β1 profibrotic signalling, which suggests that HSPB5 could be a new ...
Pierre‐Marie Boutanquoi   +17 more
wiley   +1 more source

Systemic EP4 receptor agonist and Arginase‐1 therapy in a murine model of chronic asthma and influenza virus‐induced asthma exacerbation

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 12, Page 2803-2820, June 2025.
Background and Purpose Myeloid‐derived suppressor cells (MDSCs) play important roles in the pathogenesis of asthma. Recent studies demonstrate that their function can be modulated by different pharmacological approaches. In this study, we focussed on the effects of systemically administered prostaglandin EP4 receptor agonist L‐902,688 and pegylated ...
Tim Lange   +7 more
wiley   +1 more source

Characterizing the Emergence of Myeloid‐Derived Suppressor Cell Subsets in a Murine Model of Pulmonary Fibrosis

open access: yesThe FASEB Journal, Volume 39, Issue 10, 31 May 2025.
We hypothesize that myeloid‐derived suppressor cells (MDSCs) might be able to ameliorate pulmonary fibrosis (PF) by inhibiting local inflammation and thus its transition to fibrosis. Various parameters were assessed on days 3, 7, 14, and 21, following bleomycin challenge in mice.
Nora Vedder   +8 more
wiley   +1 more source

Intratracheal Anesthesia.

open access: bronze, 1927
Stanley Rowbotham
openalex   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

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