Results 121 to 130 of about 58,052 (292)

Derivation and validation of a formula for paediatric tracheal tube size using bootstrap resampling procedure

open access: yesIndian Journal of Anaesthesia, 2019
Background and Aims: The accuracy of age-, length- and weight-based formulae to predict optimal size of uncuffed tracheal tubes (TTs) in children varies widely.
M Ganesh Kumar   +4 more
doaj   +1 more source

Caveolin-1 Is a Central Mediator of Acute Lung Injury in an Animal Model of Sickle Cell Disease. [PDF]

open access: yesPulm Circ
ABSTRACT Acute chest syndrome in sickle cell disease (SCD) carries high morbidity and mortality, with up to 15% of patients requiring invasive mechanical ventilation. However, the rates and mechanisms of ventilator‐induced lung injury (VILI) in SCD remain poorly understood.
Prohaska CC   +6 more
europepmc   +2 more sources

Telomerase modRNA Offers a Novel RNA‐Based Approach to Treat Human Pulmonary Fibrosis

open access: yesAging Cell, EarlyView.
Recombinant linear and circular hTERT mRNA restore telomerase activity in primary ATII cells and ex vivo lung tissue from patients with pulmonary fibrosis, leading to telomere elongation, reduced DNA damage, and decreased senescence and fibrosis markers.
Jia Li Ye   +14 more
wiley   +1 more source

Matrix Stiffness Promotes DRP1‐Mediated Myofibroblast Senescence to Drive Silica‐Induced Pulmonary Fibrosis

open access: yesAging Cell, EarlyView.
These findings identify matrix stiffness‐driven cellular senescence as a critical mechanism in silicosis progression, providing a rationale for targeting senescent cells as an antifibrotic therapeutic strategy. ABSTRACT Silicosis is an occupational lung disease characterized by diffuse pulmonary fibrosis resulting from inhalation of silica particles ...
Xinying Zeng   +8 more
wiley   +1 more source

A prospective observational study of predictors of difficult intubation in Indian patients

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2019
Background and Aims: During routine preoperative assessment of patients one of the commonest practices is predicting difficulty of intubation. The present study was undertaken to evaluate parameters associated with difficult intubation and to test on new
Harsha H Narkhede   +2 more
doaj   +1 more source

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

open access: yesAllergy, EarlyView.
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong   +217 more
wiley   +1 more source

EFFECT OF DOPED CERIUM OXIDE NANOPARTICLES ON THE HAEMATOLOGY OF RATS [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2016
Cerium is a rare earth lanthanide and a strong oxidizing agent. It has got a wide range of application from engendering to medicinal field. Potential amount of harm also reported about this particle.
R. Sovan   +4 more
doaj  

Antimicrobial prescribing guidelines for horses in Australia

open access: yesAustralian Veterinary Journal, EarlyView.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt   +18 more
wiley   +1 more source

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