Results 131 to 140 of about 51,241 (251)

The prevalence of cocaine-associated chest pain in a London hospital [PDF]

open access: yes, 2004
Objectives: To determine the prevalence of cocaine misuse in patients presenting to an Accident and Emergency department with chest pain.
Bandeeri, N.   +3 more
core  

IL‐17A Promotes NETs Formation via the PKCζ–ERK–ROS–PAD4 Pathway in a Mouse Model of Ischemic Stroke

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Our study demonstrates that IL‐17A promotes NET formation by upregulating PAD4 through the PKCζ–ERK–ROS pathway, thereby exacerbating ischemic brain injury. IL‐17A regulates NET formation through this newly identified molecular pathway, and targeting this pathway may offer a novel therapeutic strategy for stroke.
Chang Liu   +7 more
wiley   +1 more source

Case report: Tenecteplase for acute ischemic stroke after heparin reversal

open access: yesFrontiers in Stroke
Intravenous thrombolysis can be administered to appropriate patients with suspected acute ischemic strokes who are on intravenous heparin infusions after its rapid reversal with protamine sulfate.
Manali Desai   +4 more
doaj   +1 more source

GALNT3 Inhibits the Progression of Cerebral Ischemia–Reperfusion Injury by Stabilizing TREM2 via O‐GalNAc Glycosylation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
The neuroprotective effect of GALNT3 against CIRI and the underlying mechanisms. GALNT3 directly interacts with and catalyzes the mucin‐type O‐GalNAcylation of TREM2 predominantly at serine 147, which enhances TREM2 protein stability. This GALNT3‐TREM2 axis suppresses the release of pro‐inflammatory cytokines, oxidative stress, and activation of M1 ...
Xinyi Fei   +4 more
wiley   +1 more source

High Resolution Magnetic Resonance Vessel Wall Imaging: A Valuable Addition to Stroke Work‐Up

open access: yesEuropean Journal of Neurology, Volume 33, Issue 3, March 2026.
ABSTRACT Background Intracranial High‐Resolution Vessel Wall (HRVW) MRI is sometimes used alongside standard ischemic stroke (IS) work‐up, yet its clinical and therapeutic interests remain debated. We aimed to assess the intracranial HRVW‐MRI findings in IS patients and their impact on the IS etiologic classification as well as on treatment ...
Grace Adwane   +4 more
wiley   +1 more source

Total Bolus Transit Time Predicts Cardiac Dysfunction in Acute Ischemic Stroke and Transient Ischemic Attack Patients: A Retrospective Double Center Study

open access: yesEuropean Journal of Neurology, Volume 33, Issue 3, March 2026.
This study investigates the association between total bolus transit time, measured during emergency brain CT‐Angiography as the ΔT100‐40HU, and cardiac function in patients with ischemic stroke or transient ischemic attack (TIA). We observed an inverse correlation between ΔT100‐40HU and left ventricular ejection fraction, indicating that longer transit
Simone Bellavia   +13 more
wiley   +1 more source

Predictive value of the BDH2–MN2 nomogram model for prognosis at 3 months after receiving intravenous thrombolysis in patients with acute ischemic stroke

open access: yesArchives of Medical Science
Introduction The present study focused on developing a nomogram model to predict the 3-month survival of patients with acute ischemic stroke (AIS) receiving intravenous thrombolysis with tissue plasminogen activator (tPA).
Ynglei Li, Ning Li, Lingyun Xi, Litao Li
doaj   +1 more source

Clinical Significance of Microembolic Signal Detection in Acute Ischemic Stroke: Insights Into Ongoing Cerebral Embolization and Occult Etiologies

open access: yesEuropean Journal of Neurology, Volume 33, Issue 3, March 2026.
In this prospective study of anterior circulation AIS patients, microembolic signals (MES) were detected in 16% of cases, absent in lacunar stroke. MES presence was linked to multiple‐territory infarcts, newly diagnosed atrial fibrillation, and cancer‐associated stroke.
Eleni Bakola   +16 more
wiley   +1 more source

Advances in emerging therapies 2008 [PDF]

open access: yes, 2009
Higgins, P., Lees, K.R.
core   +1 more source

“Calcified clot march” after intravenous thrombolysis

open access: yesAnnals of Indian Academy of Neurology, 2020
Vivek Agarwal   +4 more
openaire   +3 more sources

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