Results 61 to 70 of about 51,241 (251)

Using Tenecteplase for Acute Ischemic Stroke: What Is the Hold Up? [PDF]

, 2020
Alteplase is the only Food and Drug Administration-approved intravenous (IV) thrombolytic medication for acute ischemic stroke. However, multiple recent studies comparing tenecteplase and alteplase suggest that tenecteplase is at least as efficacious as ...
Ataya, Ramsey, Brea, Isabel, Zitek, Tony
core  

Comparison of predictive scores of symptomatic intracerebral haemorrhage after stroke thrombolysis in a single centre [PDF]

, 2015
Peer reviewedPublisher ...
Dai, D., MacLeod, MJ, Reid, J. M., Watson-Fargie, T.   +3 more
core   +1 more source

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Pharmaco – Mechanical management of acute massive pulmonary embolism in a postpartum female

Indian Heart Journal, 2014
Background: The optimal use of pharmaco-mechanical therapy is not clear in the management of the acute massive pulmonary thromboembolism. Methods: A 30-year-old postpartum female presented with acute massive pulmonary embolism and was managed with ...
Sandeep Goel, Ranjit Nath, Neeraj Pandit
doaj   +1 more source

Dynamic Decrease in Eosinophil After Intravenous Thrombolysis Predicts Poor Prognosis of Acute Ischemic Stroke: A Longitudinal Study

Frontiers in Immunology, 2021
Background and PurposeBlood eosinophil counts are thought to be associated with atherosclerosis in acute ischemic stroke (AIS) and AIS severity. We aimed to investigate 1): the temporal profile of eosinophil in AIS patients treated with recombinant ...
Dehao Yang, Honghao Huang, Honghao Huang, Yiyun Weng, Junli Ren, Junli Ren, Chenguang Yang, Chenguang Yang, Jianing Wang, Jianing Wang, Beibei Gao, Tian Zeng, Tian Zeng, Jingyu Hu, Jingyu Hu, Wenjing Pan, Wenjing Pan, Fangyue Sun, Fangyue Sun, Xinbo Zhou, Xinbo Zhou, Guangyong Chen   +21 more
doaj   +1 more source

Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) magnetic resonance metabolic imaging identifies the penumbra following acute ischemic stroke [PDF]

, 2018
The ability to identify metabolically active and potentially salvageable ischaemic penumbra is crucial for improving treatment decisions in acute stroke patients.
Brennan, David, Deuchar, Graeme A., Holmes, William M., Macrae, I. Mhairi, Santosh, Celestine, Shaw, Martin   +5 more
core   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Safety of thrombolysis in acute ischemic stroke patients with previous aortic abdominal aneurysm repair

Journal of Stroke and Cerebrovascular Diseases
Objective: Intravenous thrombolysis is the standard treatment for acute ischemic stroke (AIS), but its safety in patients with a history of abdominal aortic aneurysm (AAA) repair remains unclear.
Walter Duarte-Celada, MD, Katherine Rivas, MD, Pichatorn Suppakitjanusant, MD, Pamela Davila-Siliezar, MD, Myriam Vijil, MD, Ximena Gamboa, MD, Chanaka N. Kahathuduwa, MD, PhD, Riichi Ota, MD, Ross Raedeke, Darko Quispe-Orozco, MD   +9 more
doaj   +1 more source

The mechanisms of reperfusion during in stroke patients treated with intravenous thrombolysis

Неврология, нейропсихиатрия, психосоматика, 2012
Systemic (intravenous) thrombolysis with recombinant tissue plasminogen activator (rt-PA) is a proved effective treatment modality in a certain group of patients with ischemic stroke (IS) in the first 4.5 hours after the onset of neurological symptoms ...
Maksim Alekseyevich Domashenko, M Yu Maksimova, M A Loskutnikov, A A Nikonov, V V Bryukhov, A S Suslin, M V Dreval, R N Konovalov   +7 more
doaj   +1 more source

Thrombolysis in very elderly people: controlled comparison of SITS international stroke thrombolysis registry and virtual international stroke trials archive [PDF]

, 2010
<p>Objective To assess effect of age on response to alteplase in acute ischaemic stroke.</p> <p>Design Adjusted controlled comparison of outcomes between non-randomised patients who did or did not undergo thrombolysis.
Ahmed, N., Andersen, G., Egido, J.A., Lees, K.R., Lindsberg, P.J., Mishra, N.K., Ringleb, P.A., Wahlgren, N.G.   +7 more
core   +1 more source