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Biochemical Pharmacology, 1987
Pseudoracemic hexobarbital (HB), consisting of equal molar fractions of S (+) HB and deuterium-labeled R (-) HB, d3 R (-) HB, was administered orally to rats in a dose of 50 mg/kg. Concentrations of both enantiomers in blood were measured by an enantioselective mass fragmentographic assay.
van der Graaff, M +3 more
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Pseudoracemic hexobarbital (HB), consisting of equal molar fractions of S (+) HB and deuterium-labeled R (-) HB, d3 R (-) HB, was administered orally to rats in a dose of 50 mg/kg. Concentrations of both enantiomers in blood were measured by an enantioselective mass fragmentographic assay.
van der Graaff, M +3 more
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Journal of Pharmacokinetics and Biopharmaceutics, 1983
The influence of altered drug binding on the hepatic elimination of tolbutamide, a drug of low intrinsic clearance, and on the formation of its metabolite, hydroxytolbutamide, was examined under linear conditions at steady state in the isolated in situ single-pass perfused rat liver preparation, with perfusate flow fixed at 15 ml/min.
W L, Schary, M, Rowland
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The influence of altered drug binding on the hepatic elimination of tolbutamide, a drug of low intrinsic clearance, and on the formation of its metabolite, hydroxytolbutamide, was examined under linear conditions at steady state in the isolated in situ single-pass perfused rat liver preparation, with perfusate flow fixed at 15 ml/min.
W L, Schary, M, Rowland
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Clearly There is Intrinsic Value in Intrinsic Clearance
Hepatology, 1983R K, Roberts, S, Schenker
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CLEARANCE AND BIOLOGIC HALF-LIFE AS INDICES OF INTRINSIC HEPATIC METABOLISM
The Journal of Pharmacology and Experimental Therapeutics, 1974D, Perrier, M, Gibaldi
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Identifying the intrinsic anti-site defect in manganese-rich NASICON-type cathodes
Nature Energy, 2023Xiaohui Rong, Yaxiang Lu, Jun-Mei Zhao
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Lessons in self-defence: inhibition of virus entry by intrinsic immunity
Nature Reviews Immunology, 2021Saliha Majdoul, Alex A Compton
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The rapidly changing landscape in mature T‐cell lymphoma (MTCL) biology and management
Ca-A Cancer Journal for Clinicians, 2020Enrica Marchi
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Autophagy and autophagy-related pathways in cancer
Nature Reviews Molecular Cell Biology, 2023, Kevin M Ryan
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Extrinsic (P32)/Intrinsic (P31) Phosphorus Clearance Ratio in Man
Scandinavian Journal of Clinical and Laboratory Investigation, 1954G, ØSTLING, G, TØTTERMAN
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